Clinical trials: sponsored by Poitiers University Hospital
NASAL POLYPS
Anatomo-clinico-biological Profiles in Severe Nasal Polyps
Nasal sinus polyposis is a chronic inflammatory pathology of the nasal cavity and sinus cavities that causes bilateral and multifocal polyp development and has a prevalence of 2 to 4% in the general population.
- Trial name
- NCT06362122
- Testing
- identification anatomo-clinico-biological profiles
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Chest Pain
Diagnostic Evaluation of Out-of-hospital High-sensitivity Troponin I in Patients Presenting Chest Pain
Conducting an analysis of the clinical performance of high-sensitivity cardiac troponin I, tested in the out-of-hospital setting, for ruling out cardiac origin in acute onset chest pain.
- Trial name
- VALIDATE (NCT04950244)
- Testing
- High-sensitivity cardiac troponin I (hs-cTnI)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Poitiers University Hospital
Antibiotic Prophylaxis, Colorectal Surgery
Intermittent Cefoxitin Administration Versus Loading Bolus Followed by Continuous Infusion for the Prevention of Surgical Site Infection in Colorectal Surgery
The goal of this prospective, multicentre, double-blind, randomized clinical trial is to compare intermittent cefoxitin administration to loading bolus followed by continuous infusion for surgical antibiotic prophylaxis in…
- Trial name
- PROPHYLOXITIN (NCT05755789)
- Testing
- Loading bolus of cefoxitin, Intermittent cefoxitin, Continuous infusion of cefoxitin
- Where
- 19 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Poitiers University Hospital
Respiratory Tract Viral Infection
Assessement of Viral Shedding Duration After a Respiratory Tract Infection in Oncology and Hematology Patients
The purpose of this study is to assess the duration of the viral shedding in hematology and oncology patients after a respiratory tract viral infection.
- Trial name
- ONCOVIR (NCT03389997)
- Testing
- nasal swabs
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Poitiers University Hospital
End Stage Renal Disease (ESRD)
Comparison of the Removal of Uremic Toxins With Medium Cut-off and Super High-flux Vitamin E-coated Dialyzers
End-stage renal disease (ESRD) induces an accumulation of uremic toxins responsible for increased morbidity and mortality. These toxins cover a wide range of molecules, classified according to their molecular weight as small-size…
- Trial name
- E-FLUX (NCT05610683)
- Testing
- Hemodialysis sessions using SHFVE dialyzer (VieX™) or the MCO (Theranova 500™) dialyzer
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Poitiers University Hospital
Traumatic Knee Injury, Knee
Exploration of Knee Injuries Using 3 Tesla and 7 Tesla Magnetic Resonance Imaging at the University Hospital of Poitiers
The knee is the most stressed and exposed joint in sports practice (70 to 85% of Anterior Cruciate Ligament ruptures occur during sports activities).
- Trial name
- MR7T-KneeTraum (NCT05895656)
- Testing
- 7 Tesla MRI
- Sponsor
- Poitiers University Hospital
Smoking Cessation
Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in Health Staff
The study is a randomized, controlled trial comparing music therapy associated to NRT versus NRT alone to evaluate the value of music therapy in improving the management of craving among 50 health staff smokers.
- Trial name
- MUSMOKHEALTH (NCT06130423)
- Testing
- Music intervention, Nicotine replacement
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
Ultrasonography, Obstetrics
Evaluation of Image Quality in Obstetrical Ultrasonography: Comparison Between Subjective Assessment and Contrast-to-noise Ratio
The goal of this observational study is to determine whether the subjective assessment of the quality of obstetrical ultrasonography pictures can be similar to that of an objective tool.
- Trial name
- NCT06265974
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Poitiers University Hospital
Ultrasonography, Obstetrics
Maternal and Fetal Characteristics Influencing Image Quality in Prenatal Ultrasonography
The objective of this observational study is to identify maternal and fetal characteristics that impact image quality in prenatal ultrasonography.
- Conditions
- Ultrasonography, Obstetrics, Fetus, Pregnant Women
- Trial name
- NCT06265987
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Poitiers University Hospital
Hypoxia, Cryostimulation
Evaluation of the Response to Hypoxia at Rest and During Exercise in a Healthy Subject After a Cryostimulation Exposure
Many information is available regarding human adaptations to cold or hypoxia. Adaptations to these environments and physical exercise constitute responses to physiological stress aimed at amplifying the organism's reactions and…
- Conditions
- Hypoxia, Cryostimulation, Metabolism, Autonomic Nervous System
- Trial name
- CRYOX (NCT06174480)
- Testing
- Cryostimulation
- Where
- 2 sites in France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Tourette Syndrome
Atomoxetine in Patients With Tourette's Syndrome
The purpose of this pilot study is to evaluate the effects of Atomoxetine, a selective noradrenaline reuptake inhibitor, on impulsivity in patients with Tourette's syndrome.
- Trial name
- ATO-TS (NCT04354103)
- Testing
- Atomoxetine
- Where
- 3 sites in France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Non Invasive Ventilation, Acute Respiratory Failure
Prevalence of an Early Success of Non-invasive Ventilation in the Emergency Departement.
Non-invasive ventilation is a mechanical ventilation who provides ventilatory support through a facemask, and without the need for tracheal intubation.
- Trial name
- VENTIRU (NCT06213623)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Poitiers University Hospital
Lens Diseases
Accuracy of Intra Ocular Lens CARLEVALE Calculation
The purpose of this study is to assess the accuracy of intra ocular lens power calculation using the new Carlevale sutureless scleral fixation posterior chamber intra ocular lens.
- Trial name
- NCT05368870
- Testing
- Carlevale implantation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Poitiers University Hospital
Ultrasound Therapy; Complications, Septic Arthritis
Exploratory Study of Ultrasound Signs of Native Septic Arthritis of the Knee
Primary objective: Description of ultrasound abnormalities seen in native septic arthritis of the knee during each visit. Primary endpoint: Describe the ultrasound abnormalities observed on Day 0, Day 10, 6 weeks, 3 months, 6…
- Conditions
- Ultrasound Therapy; Complications, Septic Arthritis, Knee Arthritis
- Trial name
- USAK (NCT04952220)
- Testing
- ultrasound
- Where
- 7 sites in France
- Volunteers
- 30 people
- Sponsor
- Poitiers University Hospital
Chronic Myeloid Leukemia
International Chronic Myeloid Leukemia Pediatric Study
The purpose of the study is to describe and characterize CML in a large pediatric cohort of patients.
- Trial name
- ICMLPed (NCT01281735)
- Where
- 20 sites in Australia, Austria and 18 more
- Volunteers
- 750 people
- Sponsor
- Poitiers University Hospital
Brain Injury
Comparison of Two Initial Evaluation Scales of the Severity of Brain Injury Adults Patients on the Neurological Outcome at 6 Months
Prospective cohort study. Any patient with potential cerebral injured (medical or traumatic) will be included in the study, regardless of its severity, history, the presence of anticoagulant or antiagrégant.
- Trial name
- CASSANDRA (NCT03157453)
- Where
- France
- Volunteers
- 367 people
- Sponsor
- Poitiers University Hospital
Reality Device, Reduction Procedure
Pilot Study on the Evaluation of the Effectiveness of a Virtual Reality Device on Anxiety During Procedural Sedation in Traumatology in Emergency Department
The aim of this study is to evaluate the efficiency of a reality device and a virtual hypnosis software to reduce the anxiety during reduction procedure in traumatology in an emergency department.
- Conditions
- Reality Device, Reduction Procedure, Fracture, Dislocation
- Trial name
- VIRTUAL DREAM (NCT04936880)
- Testing
- Experimental : Virtual reality + analgesia-sedation, Control: Analgesia-sedation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Poitiers University Hospital
Soluble Urokinase Plasminogen Activation Receptor, Abdominal Pain
Prognostic Value of Soluble Urokinase Plasminogen Activation Receptor (SUPAR) to Rule Out Complications in Patients Admitted in Emergency Department for Acute Abdominal Pain.
Soluble Urokinase Plasminogen Activation Receptor (SUPAR) is a validated biomarker with applications in the study of inflammation and infection.
- Conditions
- Soluble Urokinase Plasminogen Activation Receptor, Abdominal Pain, Emergency Department, Mortality
- Trial name
- GRADIENT (NCT05580016)
- Testing
- Soluble Urokinase Plasminogen Activation Receptor measurement
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Head and Neck Cancer, Cytokine
Study of the Role of Oncostatin M in Head and Neck Squamous Cell Carcinoma
The ROMCOR study will be interested in the impact and the role of oncostatin M (OSM), a cytokine belonging to IL-6 superfamily, in the physiopathology of head and neck squamous cell carcinoma.
- Trial name
- NCT06199947
- Testing
- Biopsies and Blood collection
- Volunteers
- 119 people
- Sponsor
- Poitiers University Hospital
Waldenstrom's Macroglobulinaemia Refractory
Patients Treated in Real Life With VEnetoclax for WAldenström Macroglobulinemia
Waldenström macroglobulinemia (WM) is an incurable disease. BCL2 antagonist, an important anti-apoptosys molecule, is already approved for the treatment of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia.
- Trial name
- NCT06200220
- Testing
- Venetoclax
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Poitiers University Hospital