Clinical trials: sponsored by Poitiers University Hospital
Postoperative Residual Curarization
Comparison of Train of Four, Tetanus 50 and 100 Hz Recovery After Rocuronium Block Reversed by Sugammadex
Despite neuromuscular transmission monitoring and pharmacological reversal allowing a train of four ratio recovery higher than 0.9, patients receiving neuromuscular blocking agent during general anesthesia have a high risk of…
- Trial name
- NCT05003024
- Testing
- TOF SCAN, ITF
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Poitiers University Hospital
Failed Back Surgery Syndrome
Study Comparing Conventional, Burst and High Frequency (HF) Spinal Cord Stimulation (SCS) in Refractory Failed Back Surgery Syndrome (FBSS) Patients After a 32-contact Surgical Lead Implantation
Chronic Back and/or Leg Pain (CBLP) after spinal surgical procedures, a condition commonly labelled Failed Back Surgery Syndrome (FBSS), affects between 15% and 40% of patients after a spine surgery.
- Trial name
- MULTIWAVE (NCT03014583)
- Testing
- Precision Spectra™ system
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Poitiers University Hospital
Vigilance Dysfunction
Study of the Reversibility of Vigilance Dysfunction at 6 Months of Continuous Positive Airways Pressure (CPAP) in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)
It is a monocentric prospective pilot study in Poitiers University Hospital, specifically analyzing the vigilance disorders in the Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and their reversibility after 6 months of…
- Trial name
- VISA (NCT03344263)
- Testing
- tests of attentional performance
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Poitiers University Hospital
COVID-19, Chilblains
Analysis of Chilblains pROfile During coVID-19 Epidemic (ACROVID)
Cases of chilblains have been reported with an unusual frequency in France in the context of the COronaVirus Infectious Disease 2019 (COVID-19) epidemic.
- Trial name
- ACROVID (NCT04387955)
- Testing
- Biological Sample Collection
- Where
- France
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Chemeotherapy, Immunotherapy
Clinical and Psycho-social Impact of COVID-19 Related Confinement on Patients With Digestive Tumors
To limit Corona virus dissemination on its territory, France applied strict confinement from March 16th to May 11th. Scientific societies recommended treatment modifications and remote consultations that were applied.
- Conditions
- Chemeotherapy, Immunotherapy, Treatment Mofidied, Coronavirus
- Trial name
- COVIDICA (NCT04389684)
- Testing
- Psycho-Social Questionnaire
- Where
- 3 sites in France
- Volunteers
- 102 people
- Sponsor
- Poitiers University Hospital
Radiography, Emergencies
PARamedical Abnormalties Detection of Traumatic Bone Lesion of the extremitIeS
This study assesses the performance of radiographers in detecting radiological anomalies of the appendicular skeleton in emergency department.
- Conditions
- Radiography, Emergencies, Diagnostic
- Trial name
- PARADIS_1 (NCT05076188)
- Testing
- Emergency radiography
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Failed Back Surgery Syndrome
Subcutaneous Peripheral Nerve Stimulation (PNS) as "Hybrid Stimulation" After Failure of Spinal Cord Stimulation (SCS) to Control the Back Pain Component in Failed Back Surgery Syndrome (FBSS) Patients.(CUMPNS Study)
Despite globally favourable outcomes of Spinal Cord Stimulation (SCS), a significant proportion of Failed Back Surgery Syndrome (FBSS) patients do not obtain adequate coverage of low back pain.
- Trial name
- NCT02110888
- Testing
- Subcutaneous peripheral nerve stimulation, SCS Only
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Poitiers University Hospital
Chronic Consumption of Cannabis
Cannabinoides Concentrations and Hyperemesis Syndrom Occurrence in Regular Cannabis Consumer (CANEMESE)
The Cannabinoide Hyperemesis Syndrom (CHS) is defined as a recurrent syndrome of intractable vomiting that occurs in chronic cannabis consumers. The diagnosis is linked to clinical criteria only.
- Trial name
- NCT04836611
- Testing
- 1 blood sample
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Parkinson's Disease
Impulsivity and Parkinson's Disease : a Neuropsychology With Magnetic Resonance Imaging Study
This study aims to characterize the nature of impulsivity in Parkinson's Disease (PD).
- Trial name
- NCT02463617
- Testing
- magnetic resonance imaging
- Where
- 3 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Resectable Hepatic Metastases of Colorectal Cancer
Study of Immune Response and Liver Damage Induced by Chemotherapy for Liver Metastases of Colorectal Cancer
The immune response at primary tumor has a major role in the prognosis of colorectal cancer (CRC). Some studies suggest a prognosis value of cytotoxic T cell and memory T cells at primary tumor greater than tumoral stage.
- Trial name
- METAHEP (NCT01673607)
- Testing
- Biopsie liver
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Poitiers University Hospital
Pain, Actinic Keratosis
Pain Management During a Photodynamic Therapy Session on the Vertex for Actinic Keratosis: Tumescent Anesthesia Interest
This study focus on the efficacity of tumescent anesthesia in pain management during a photodynamic therapy on the vertex for treatment of actinic keratosis.
- Conditions
- Pain, Actinic Keratosis, Analgesia, Phototerapy
- Trial name
- ANTUKA (NCT04779255)
- Testing
- Procedure (Tumesent anesthesia), Control Arm (Paracetamol)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Poitiers University Hospital
Surgery, 75 Years Old and More
Place of Comprehensive Geriatric Assessment in Patients ≥ 75 Years Care, With Breast Cancer, After Screening With FOG (Oncology Geriatric Filter)
The risk of diagnosis of cancer increases with age, especially breast cancer in elderly women. Elderly population is heterogeneous, regarding physiological reserves, comorbidities, disability and geriatric conditions.
- Conditions
- Surgery, 75 Years Old and More, Female Breast Cancer
- Trial name
- NCT03059875
- Testing
- Medical consultation for a Standardized Geriatric Evaluation
- Where
- 6 sites in France
- Volunteers
- 79 people
- Sponsor
- Poitiers University Hospital
Colorectal Cancer
The Life and Care of Patients With Colorectal Cancer Before Age 65 and Their Kindred
In a context the respect of the autonomy of the patients is important, it is necessary to pay a sustained attention to the experiences and the lived experience as well of the patients suffering or in remission of cancer as of…
- Trial name
- MACHROAPIK (NCT04451343)
- Testing
- biographical interviews
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Poitiers University Hospital
Knee Surgery, Rehabilitation
Benefits of Observing Point-light Displays in Postoperative Rehabilitation of the Total Knee Prosthesis.
The LOARAL project concerns patients who have undergone total knee arthroplasty to treat symptomatic osteoarthritis. Patient will be divided into two groups: a control group where patients will do standard rehabilitation and an…
- Conditions
- Knee Surgery, Rehabilitation, Point Light Display
- Trial name
- LOARAL (NCT03856983)
- Testing
- Point light display
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Poitiers University Hospital
Systemic Sclerosis, Diaphragm Defect
Muscular Respiratory Involvement and Systemic Sclerosis
Dyspnea in systemic sclerosis (ScS) constitute a major factor of functional disability. Intensity of dyspnea is sometimes discordant with objectives data from cardiopulmonary involvements, suggesting unknown additional factors.
- Conditions
- Systemic Sclerosis, Diaphragm Defect, Respiratory Insufficiency, Pulmonary Function Test
- Trial name
- SIROCO (NCT04118725)
- Testing
- Pulmonary function test
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Poitiers University Hospital
Myopic Choroidal Neovascularisation
Real Life Study in Myopic Neovascularization
This is a multi centre, single arm, prospective observational phase 4 study in naive or pretreated patients with myopic neovascularization.
- Trial name
- VIC (NCT03797547)
- Testing
- AFLIBERCEPT
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Poitiers University Hospital
Respiratory Failure
EX-PO Trial : Evaluation of the Occlusion Pressure (PO.1) in Extubation Failure
Measuring bedside occlusion pressure in neurosurgical or surgical critically ill patients could tell us about the patient's respiratory drive, and therefore, tell us whether or not extubation will be successful.
- Trial name
- NCT04654273
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Poitiers University Hospital
Pregnancy
In Vivo Assessment of the Elastic Properties of Women's Pelvic Floor During Pregnancy
The investigators hypothesize that optimize our risk prediction for pelvic floor disorders after childbirth by taking into account intrinsic women's pelvic floor characteristics and their changes during pregnancy.
- Trial name
- ELASTOPELV (NCT03602196)
- Testing
- Perineal ultrasound assessment, Peripheral muscles assessment, Clinical pelvic floor assessment
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Obstetric Anal Sphincter Injury, Episiotomy Wound
Mediolateral Episiotomy and Obstetric Anal Sphincter Injuries in Instrumental Delivery
Literature is contradictory about the impact of mediolateral episiotomy during operative vaginal delivery in obstetric anal sphincter injuries prevention explaining the absence of international guidelines.
- Conditions
- Obstetric Anal Sphincter Injury, Episiotomy Wound, Anal Incontinence, Pelvic Floor Disorders
- Trial name
- INSTRUMODA (NCT04446780)
- Testing
- Mediolateral episiotomy
- Where
- France
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Bloodstream Infection, Acute Myeloid Leukemia
Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia
There is no specific recommendation about antimicrobial treatment length for documented infections in chemotherapy induced febrile neutropenia.
- Conditions
- Bloodstream Infection, Acute Myeloid Leukemia, Febrile Neutropenia
- Trial name
- NCT04910698
- Testing
- Antibiotic
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Poitiers University Hospital