Clinical trials: sponsored by Radboud University Medical Center
Wounds and Injuries, Wrist Injuries
Volume CT of the Wrist and Carpus After Trauma
The purpose of this study is to evaluate whether standard volume computed tomography (CT) has impact on treatment in patients with suspicion of fractures of the wrist and carpus.
- Trial name
- VuisT (NCT01857570)
- Testing
- Volume Computed Tomography of the wrist and carpus
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Sepsis
Effects of BCG on Immune Response
In the present study, we want to investigate whether BCG-vaccination enhances the innate immune response in humans in vivo during (single) human endotoxemia.
- Trial name
- NCT02085590
- Testing
- BCG vaccine, Lipopolysaccharide (LPS) E. Coli 1 ng/kg intravenously
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Malnutrition, Dietary Modification
Basic Care Revisited: Early Nutrition Intervention for Outpatients
Early nursing nutrition intervention for outpatients in need of surgery Objective - To investigate the feasibility and effectiveness of screening and an early nursing intervention on malnutrition in outpatients in need for…
- Trial name
- BCR_N (NCT02440165)
- Testing
- Nursing nutrition intervention
- Where
- 2 sites in Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Diabetes, Hypoglycemia Unawareness
The Effect of Antecedent Hypoglycaemia on β2-adrenergic Sensitivity
Hypoglycaemia unawareness is a common complication in patients with type 1 diabetes and with insulin-treated type 2 diabetes of long duration.
- Trial name
- NCT00160056
- Testing
- Hypoglycemia
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cancer
Hd-bronchoscopy, Comparison to Standard White Light and Autofluorescence Bronchoscopy
Through technological improvement a new technique has become available in the form of high-definition (HD-) bronchoscopy. Current normal video white light bronchoscopy is the standard, and video-autofluorescence bronchoscopy…
- Trial name
- NCT01676012
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Radboud University Medical Center
Preeclampsia
Exercise Induced Improvement of the Venous Reserve Capacity in Formerly Pre-eclamptic Women
Primary objective: To investigate whether physical exercise prior to pregnancy in formerly preeclamptic women results in a comparable improvement of vascular and endothelial functioning as in women who had an uneventful…
- Trial name
- NCT00900458
- Testing
- Aerobic Exercise training
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Larynx Cancer
Patient Selection for Hypoxia Modifying Treatments in Larynx Carcinomas
The purpose of this study is to identify in a prospective manner microregional profiles of oxygenation and proliferation based on exogenous and endogenous markers that are predictive for outcome of radiotherapy in squamous cell…
- Trial name
- NCT00160095
- Where
- 5 sites in Netherlands
- Volunteers
- 79 people
- Sponsor
- Radboud University Medical Center
Larynx Carcinoma
Randomized Trial of ARCON in Larynx Cancer
TITLE: A multicentre, randomised, phase III clinical trial comparing accelerated radiotherapy with accelerated radiotherapy plus carbogen and nicotinamide (ARCON) in clinical stage T2-4 laryngeal carcinoma.
- Trial name
- NCT00147732
- Testing
- Accelerated radiotherapy, ARCON
- Where
- 7 sites in Netherlands, United Kingdom
- Volunteers
- 345 people
- Sponsor
- Radboud University Medical Center
Head and Neck Neoplasms
Validation of 18F-MISO-PET and 18F-FLT-PET
Hypoxia and tumor cell proliferation are important mechanisms contributing to resistance to radiotherapy in human head and neck tumor cells.
- Trial name
- NCT00159978
- Testing
- 18F-FLT and 18F-MISO-PET
- Where
- Netherlands
- Volunteers
- 21 people
- Sponsor
- Radboud University Medical Center
Out of Hours Medical Care, Primary Health Care
The (Cost-)Effectiveness of Nurse Practitioners Working at the Primary Out of Hours Emergency Service
The aim of this study is to explore whether the implementation of Nurse Practitioners can lead to a more accessible and efficient patient care at the primary out of hours service.
- Trial name
- NCT01388374
- Testing
- Other, care provided by Nurse Practitioners
- Where
- Netherlands
- Volunteers
- 12,092 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Communication, Patient Participation
Basic Care Revisited_Communication for Patient Participation
COMMUNICATION - Feasibility and effectiveness 'Tell-us Cards' in hospital patients Objective - To investigate the feasibility and effectiveness of 'Tell-us Cards' on patient participation in basic care in hospital settings.
- Trial name
- BCR_C (NCT02401919)
- Testing
- Tell-us Card
- Where
- 2 sites in Netherlands
- Volunteers
- 175 people
- Sponsor
- Radboud University Medical Center
Hypoxia, Hyperoxia
Effects of Oxygen Status on Hypoxia Inducible Factor 1-α and Inflammation. A Pilot Proof of Principle Study.
It has been shown in in vitro and animal models that hypoxia can have pro-inflammatory effects and hyperoxia can have anti-inflammatory effects.
- Trial name
- NCT01889823
- Testing
- Hypoxia, Hyperoxia
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Neck Pain
Effectiveness of Manual Therapy in Patients With Neck Pain.
Background of the study: Manual Therapy applied to patients with non-specific neck pain has been investigated several times, both internationally and nationally.
- Trial name
- NECKproject (NCT00713843)
- Testing
- Manual Therapy Utrecht, Physical Therapy
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Radboud University Medical Center
Inferior Alveolar Nerve Injury
The Efficacy of Cone Beam Computed Tomography (CBCT) Compared to Panoramic Radiography Prior to Third Molar Removal
The purpose of this study is to evaluate the efficacy and cost-effectiveness of Cone Beam Computed Tomography (CBCT) compared to panoramic radiography prior to removal of third molars in reducing patient's morbidity.
- Trial name
- NCT02071030
- Testing
- Third molar removal
- Where
- Netherlands
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pelvic Organ Prolapse, Cystocele
Effectiveness Prolift+M Versus Conventional Vaginal Prolapse Surgery
Pelvic organ prolapse is highly prevalent in the female population. The recurrence rate of pelvic organ prolapse after surgical treatment is high.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Rectocele, Uterine Prolapse
- Trial name
- VROUW2 (NCT02231099)
- Testing
- Prolift + M, conventional vaginal prolapse surgery
- Where
- 5 sites in Netherlands
- Volunteers
- 176 people
- Sponsor
- Radboud University Medical Center
ADHD
A Study on the Inter-Hemispheric Alpha Ratio in Kids With ADHD (SHARK)
Investigate the hypothesis that children with ADHD have difficulty with the allocation of visio-spatial attention related to an inability to control posterior alpha brain oscillations.
- Trial name
- SHARK (NCT01932398)
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Type 1 Diabetes
GLP-1 Receptor Targeting in Diabetic and Healthy Individuals
The purpose of the study is to determine whether there are differences in pancreatic uptake of the radiotracer between healthy individuals and patients with type 1 diabetes.
- Trial name
- GLP-1-CPOP (NCT01825148)
- Testing
- radiolabeled Exendin
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Innate Immune Response, Endotoxemia
In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II
Excessive inflammation is associated with tissue damage caused by over-activation of the innate immune system. This can range from mild disease to extreme conditions, such as multiple organ dysfunction syndrome (MODS) and acute…
- Conditions
- Innate Immune Response, Endotoxemia, Inflammation, Sepsis
- Trial name
- VECTORII (NCT01766414)
- Testing
- C1-esterase inhibitor, Endotoxin
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Malaria
Controlled Human Malaria Infection After Bites From Mosquitoes Infected With Two Novel P. Falciparum Strains
An effective vaccine against malaria is urgently needed to combat the scourge of this disease. Before candidate vaccines can be tested in endemic countries, they are first tested in human volunteers in so-called Controlled Human…
- Trial name
- NCT02149550
- Testing
- NF135 n=5, NF135 n=2, NF135 n=1
- Where
- 2 sites in Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Hearing Loss, Low Vision
Self-management for Dual Sensory Impaired
This study aims to determine the effectiveness of a self-management program for elderly with an acquired and concurrent hearing and visual impairment due to age-related disease processes.
- Trial name
- NCT01217502
- Testing
- Self management program
- Where
- 4 sites in Netherlands
- Volunteers
- 89 people
- Sponsor
- Radboud University Medical Center