Clinical trials: sponsored by Region Stockholm
Subarachnoid Aneurysm Hemorrhage, Cerebral Vasospasm After Subarachnoid Hemorrhage
Delayed Cerebral Infarction Beyond Endoluminal Spasmolysis and Induced Hypertension
An observational study of patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage, employing multimodal neuromonitoring.
- Trial name
- Decibel (NCT07305922)
- Testing
- Induced hypertension with norepinephrine, Endoluminal Spasmolysis
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Stockholm
Mental Disorders
Braining: Implementation of Physical Exercise for Patients in Specialist Psychiatry
The goal of this clinical trial is to compare Braining, a physical exercise lifestyle intervention in psychiatric care, with structured advice on physical exercise.
- Trial name
- NCT06012149
- Testing
- Braining, Structured advice on physical activity
- Where
- 5 sites in Sweden
- Volunteers
- 208 people
- Sponsor
- Region Stockholm
Critical Care
Prediction of the Post-intensive Care Syndrome
The goal of this observational study is to assess whether a screening of patients at discharge from the intensive care unit (ICU) can predict psychological and physical problems three months later.
- Trial name
- PREPICS (NCT05690438)
- Where
- 4 sites in Sweden
- Volunteers
- 773 people
- Sponsor
- Region Stockholm
Insomnia
Sleep Restriction Therapy for Insomnia in Primary Health Care
The recommended treatment for insomnia, cognitive behavioral therapy for insomnia (CBT-I), is effective. However, its long, multi-component nature makes it challenging to implement in ordinary primary care, where most people are…
- Trial name
- NCT04975776
- Testing
- Sleep restriction therapy, Sleep hygiene
- Where
- Sweden
- Volunteers
- 104 people
- Sponsor
- Region Stockholm
Early Gastric Cancer
Sentinel Node Resection With or Without LECS After Noncurative ESD for EGC
For patients with non-curative resection after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC), complementary surgery is generally recommended.
- Trial name
- Co-SNARE (NCT07295002)
- Testing
- ICG-guided lymphadenectomy, Laparoscopic and endoscopic cooperative surgery (LECS)
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Region Stockholm
Multiple Sclerosis, Pregnancy
Immune System Effects in Children Born to Women With Multiple Sclerosis Treated With Monoclonal Antibody Therapy During Pregnancy
The goal of this observational study is to learn about consequences for the child when the mother is treated with rituximab (or other monoclonal CD-20 antibodies) before or during pregnancy.
- Trial name
- NCT07149662
- Testing
- monoclonal CD-20 antibodies, No Drug, Other treatment
- Where
- Sweden
- Volunteers
- 111 people
- Sponsor
- Region Stockholm
Atrial Fibrillation (AF)
RECURrence of Atrial Fibrillation After Cardioversion of Patients Randomized to Dapagliflozin or Usual Care
The goal of this clinical trial is to learn if drug dapagliflozin, a sodium-glucose transport-2 inhibitor, works to treat atrial fibrillation in adults.
- Trial name
- RECUR-AF (NCT07187570)
- Testing
- Dapagliflozin 10 mg once daily
- Where
- 7 sites in Sweden
- Volunteers
- 1,600 people
- Sponsor
- Region Stockholm
Anxiety Disorder
Initial Evaluation of a Stepped Care Model for Treating Mild to Moderate Childhood Anxiety in Primary Care
Objectives: In the past ten years in Sweden, a new form of primary care units called first line mental health (FLMH) has been implemented to improve mental health services for children and adolescents.
- Trial name
- NCT05686512
- Testing
- Step-by-Step, Cool Kids
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Stockholm
Endometriosis
Biomarkers in the Endometrial Fluid, Tissue, and Follicular Fluid of Moderate/Severe Endometriosis Patients
This study aims to explore biomarkers in the endometrial fluid and tissue of women with moderate to severe endometriosis, with a specific focus on those involved in pre-receptive endometrium and embryo implantation.
- Trial name
- NCT07182643
- Testing
- Endometrial fluid, Endometrial biopsy, Follicular fluid
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Clubfoot, PBS
Video Documented PBS-Score in Children With Clubfoot
Evaluate agreement and inter-rater reliability of PBS-score assessments based on video documented material.
- Trial name
- PEVA (NCT06033638)
- Testing
- Score assessment
- Where
- Sweden
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Clubfoot
Predictive Value of the PBS-score in Children With Clubfoot
Evaluate the predictive value of the PBS-score in predicting recurrence of idiopathic clubfoot, measured as need for additional treatment.
- Trial name
- NCT06050746
- Testing
- Systematic screening
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Stockholm
Clubfoot
Therapeutic Recommendations Based on Clinical History and Video Documented PBS-Score
Determine the relationship between the PBS-score and treatment recommendations provided by senior pediatric orthopedic surgeons.
- Trial name
- NCT06050564
- Testing
- Treatment recommendations will be based on video documented PBS-Score
- Where
- Sweden
- Volunteers
- 55 people
- Sponsor
- Region Stockholm
Heart Failure
Registry BAsed Optimization Of Therapy in Heart Failure
Rationale. Although several pharmacological treatments, namely renin-angiotensin-system inhibitors, sacubitril/valsartan, beta-blockers, mineralocorticoid receptor antagonists and sodium-glucose cotransporter-2 inhibitors…
- Trial name
- REBOOT-HFrEF (NCT07154758)
- Testing
- Screening for need of HFrEF GDMT implementation through SwedeHF
- Where
- 6 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- Region Stockholm
Lung Tumor
RealMove (Lung): Assessing Tumour Motion With Dynamic MRI
The study aims to develop an improved method to tailor the geometric safety margin when treating with stereotactic body radiotherapy (SBRT), to avoid tumour cells being missed during irradiation and to limit the exposure of…
- Trial name
- RealMove(lung) (NCT06322329)
- Testing
- Dynamic MRI
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Region Stockholm
Blood Injury Phobia, Injection Fear
Exposure-Based CBT for Youth With Blood and Injection Phobia and Chronic Illness
More than half of all children fear needles, and hospitalized children often describe injections as the most frightening part of medical care.
- Trial name
- NCT07125287
- Testing
- Exposure based CBT
- Volunteers
- 30 people
- Sponsor
- Region Stockholm
Depression, Physical Inactivity
Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
"Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurement…
- Conditions
- Depression, Physical Inactivity, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT05157386
- Testing
- Braining
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Systemic Lupus Erythematosus
Subgrouping SLE - a New Approach to Understand the Pathogenesis and Improve Treatment
The goal of this observational study is to investigate different phenotypes among patients with SLE and to compare with matched general population controls.
- Trial name
- SLEsubgroups (NCT07102030)
- Where
- Sweden
- Volunteers
- 900 people
- Sponsor
- Region Stockholm
Acute Kidney Injury, Multi Organ Failure
Long Term Renal Function After CRRT in the Paediatric Intensive Care Unit, a Follow-up Study.
In this study the investigators will evaluate the long-term renal function in children treated with continuous renal replacement therapy (CRRT) due to acute kidney injury (AKI) and multiple organ failure (MOF) in the pediatric…
- Conditions
- Acute Kidney Injury, Multi Organ Failure, Children, Only
- Trial name
- NCT05629273
- Where
- Sweden
- Volunteers
- 156 people
- Sponsor
- Region Stockholm
Vestibular Disorder
Vestibular Function and Motor Development in Small Children
Infants and toddlers with and without vestibular impairment will be tested blinded by pediatric physiotherapist with different age adequate motor scales in order to find out pathological motor patterns specifically associated to…
- Trial name
- NCT07079488
- Testing
- Motor proficiency scales
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Gastric Cancer
Laparoscopic and Endoscopic Collaborative Surgery as Rescue-treatment for Advanced Gastric Cancer
The standard treatment for advanced gastric cancer without metastases is gastrectomy, where the whole stomach or a large proportion is removed surgically together with regional lymph nodes.
- Trial name
- LE-RACUS (NCT06105515)
- Testing
- Laparoscopic and Endoscopic Collaborative Surgery (LECS)
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Region Stockholm