Clinical trials: sponsored by RenJi Hospital
Pulmonary Disease
Effect of Different Oxygen Concentration on Postoperative Pulmonary Complications After Pulmonary Reexpansion
To evaluate the effect of 80% inspiratory oxygen fraction (FiO2) and 30% FiO2 on the incidence of pulmonary complications after pulmonary reexpansion following one-lung ventilation and 2-hour postoperative within the first 7 days…
- Trial name
- NCT06202586
- Testing
- low FiO2, high FiO2
- Where
- China
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Hypoxia, Gastric Cancer
High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity
Hypoxia is the most common adverse event during gastrointestinal endoscopes sedated with propofol and sufentanil, especially in obese people.
- Conditions
- Hypoxia, Gastric Cancer, Esophagus Cancer, Polyp of Colon
- Trial name
- NCT04500392
- Testing
- High-flow nasal cannula oxygenation, Regular nasal cannula
- Where
- 3 sites in China
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
Neoadjuvant Immunotherapy of Cisplatin-ineligible High Risk Upper Urinary Tract Urothelial Carcinoma
Neoadjuvant PD-1 Monoclonal Antibody in Cisplatin-ineligible High Risk Upper Tract Urothelial Carcinoma
Neoadjuvant therapy of cisplatin-based chemotherapy has been proved to improve prognosis of muscle invasive UTUC patients in several studies.
- Trial name
- NCT04672330
- Testing
- Tislelizumab
- Where
- China
- Volunteers
- 16 people
- Sponsor
- RenJi Hospital
Breast Cancer Diagnosis, Breast Cancer
A Simplified Approach to Predicting the Malignancy of Breast Lesions: Nomogram in Ultrasonography
This study aims to construct and validate a quantitative mammographic model based on breast ultrasound images, incorporating patient characteristics such as age and significant sonographic features.
- Trial name
- NCT06185855
- Testing
- Retrospective Ultrasonographic Data Analysis
- Volunteers
- 550 people
- Sponsor
- RenJi Hospital
Immune Tolerance, Liver Transplant; Complications
Immune Tolerance After Pediatric Liver Transplantation
Immunosuppressive (IS) agents are effective treatment to avoid acute or chronic rejection after pediatric liver transplantation.
- Trial name
- NCT05501301
- Testing
- IS weaning off
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Venous Thromboembolism
Chinese Community Inpatient Thromboembolism
This study is a multicenter cross-sectional study conducted at 20 centers. Data of existing inpatients in 20 community hospitals were collected.
- Trial name
- COMET (NCT06168331)
- Where
- 2 sites in China
- Volunteers
- 1,152 people
- Sponsor
- RenJi Hospital
End-Stage Renal Disease
Urgent-start Peritoneal Dialysis in ESRD Patients：A Multi-center Study
Within the last decade, urgent-start peritoneal dialysis(PD) has gained considerable interest amongst nephrologists. Several publications have provided assurances that urgent-start PD is indeed feasible and can serve patients…
- Trial name
- NCT02946528
- Testing
- urgent-start peritoneal dialysis catheter, central venous catheter
- Where
- China
- Volunteers
- 116 people
- Sponsor
- RenJi Hospital
Aortic Aneurysm, Abdominal, Iliac Aneurysm
An Exploratory Study of Iliac Artery Branch Stent for Internal Iliac Artery Reconstruction in Abdominal Aortic Aneurysm/Iliac Aneurysm Repair
The purpose of this study is to evaluate the efficacy and safety of IBD stent of Shenzhen Xianjian Company and IBE stent of American Gore company in the treatment of abdominal aortic aneurysm/iliac aneurysm reconstruction of…
- Trial name
- NCT06162273
- Testing
- IBD stent of Shenzhen Xianjian Company and IBE stent of American Gore company
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Liver Transplantation
Unplanned ICU Readmission for Pediatric Liver Transplantation
To explore the risk factors of unplanned return to Intensive Care Unit (ICU) in pediatric liver transplant recipients, and to provide data support for the transfer of pediatric liver transplant recipients from ICU after surgery…
- Trial name
- NCT06162260
- Testing
- ICU readmission
- Volunteers
- 1,575 people
- Sponsor
- RenJi Hospital
ST Elevation Myocardial Infarction
Fractional Flow Reserve Guided Immediate Versus Staged Complete Myocardial Revascularization in Patients With ST-segment Elevation Myocardial Infarction With Multivessel Disease (Future Study)
It is a prospective, multicenter, randomised controlled, open-label, blinded endpoint assessment trial, to compare the strategy of immediate complete revascularisation and staged complete revascularisation in ST-segment-elevation…
- Trial name
- NCT05967663
- Testing
- PCI-immediate complete revascularisation, PCI-staged complete revascularisation
- Where
- China
- Volunteers
- 840 people
- Sponsor
- RenJi Hospital
Liver Cirrhosis, Liver
SALT for Patients With Hepatic Cirrhosis
Hepatitis B virus (HBV) infection is a very difficult public health problem in the world. Patients often experience the trilogy of "hepatitis-cirrhosis-liver cancer".
- Trial name
- NCT06153914
- Testing
- Sequential Adult Left Lateral Liver Transplantation
- Volunteers
- 47 people
- Sponsor
- RenJi Hospital
New Onset Diabetes After Transplant, Kidney Transplant; Complications
Efficacy and Safety of Empagliflozin in NODAT
This is an open label, randomized controlled study. We'd like to access the safety and effects of empagliflozin compared with linagliptin in new-onset diabetes after kidney transplantation patients.
- Trial name
- NCT03642184
- Testing
- Empagliflozin, Linagliptin
- Where
- China
- Volunteers
- 6 people
- Sponsor
- RenJi Hospital
Acute Kidney Injury
Establish and Apply the Evaluation System of Ultrasonic Integrated Technology for Prevention and Treatment of Acute Kidney Injury
Establish an integrated evaluation system of ultrasound technology for the prognosis of acute kidney injury, and in order to achieve non-invasive, reliable early diagnosis "gold standard".
- Trial name
- NCT02347930
- Testing
- kidney ultrasound
- Where
- China
- Volunteers
- 196 people
- Sponsor
- RenJi Hospital
Diagnostic Imaging, Diagnosis
Application of Ultrasound Integrated Precision Diagnosis Technology in Prevention of Kidney Disease and Its Progress
In this study, a prospective, randomized and controlled clinical study would be carried out to establish Ultrasound Integrated Precision Diagnosis Technology with elastography as the core technology to evaluate renal injury and…
- Conditions
- Diagnostic Imaging, Diagnosis, Kidney Disease
- Trial name
- NCT04044404
- Testing
- Ultrasound Integrated Precision Diagnosis Technology(ultrasound elastography)
- Where
- 2 sites in China
- Volunteers
- 208 people
- Sponsor
- RenJi Hospital
Stroke Volume Variation, SVV-FloTrac
A Comparison of Thoracic Electrical Bioimpedance and FloTrac/Vigileo
Stroke volume variation (SVV) is an indicator used to assess the patient's volume status. The FloTrac system (Edwards Lifesciences, Irvine, CA) continuously monitors cardiac output (CO) and SVV (SVV-FloTrac) by analyzing the…
- Conditions
- Stroke Volume Variation, SVV-FloTrac, Thoracic Electrical Bioimpedance, Fluid Responsiveness
- Trial name
- NCT06143111
- Testing
- Flotrac Group, BioZ Group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Inflammatory Bowel Diseases, Clostridium Difficile Infections
Research on Gut Microbiome and Metabolomics Alterations in C.Difficile Infected IBD Patients
The goal of this research is to compare alterations of gut microbiota and fecal metabolomics alterations between inflammatory bowel disease patients infected with or without Clostridioides difficile.
- Conditions
- Inflammatory Bowel Diseases, Clostridium Difficile Infections, Microtia
- Trial name
- NCT05714566
- Testing
- Clostridioides difficile toxin detection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Atrial Fibrillation, Anticoagulants
Application of "I-Anticoagulation"in Patients With Atrial Fibrillation
The goal of this prospective, multicenter, cluster randomized controlled trial is to assess the effectiveness of a shared decision-making tool, "I-Anticoagulation", for anticoagulation management in AF patients.
- Trial name
- NCT06137794
- Testing
- Use of "I-Anticoagulation" to make the decision and manage patients
- Volunteers
- 440 people
- Sponsor
- RenJi Hospital
Peripheral Arterial Disease
The Efficacy of Heparin-boned Viabahn Endoprosthesis and Paclitaxel-coated Balloons for Complex Femoropopliteal Lesions
The purpose of this study is to evaluate the effectiveness of the Viabahn endoprosthesis for treating long femoropopliteal lesions (stenosis ≥ 25cm, occlusion ≥ 15cm) or recurrent in-stent restenosis compared to drug-coated…
- Trial name
- NCT06124755
- Testing
- Viabahn endoprosthesis group, Drug-coated balloon group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Peritoneal Dialysis Complication, Residual Kidney Function
Incremental PD With Single Icodextrin Exchange
Objectives: To investigate the efficacy and safety of single daily icodextrin exchange for initiation of incremental peritoneal dialysis (PD). Subjects: Seventy-two incident PD patients.
- Conditions
- Peritoneal Dialysis Complication, Residual Kidney Function, Survival, Health-related Quality of Life
- Trial name
- NCT06119373
- Testing
- Single daily icodextrin exchange, Conventional PD group
- Volunteers
- 72 people
- Sponsor
- RenJi Hospital
Urinary Incontinence,Stress
Correlation Between Changes in Sex Hormone Levels and Stress Urinary Incontinence in Women
The goal of this observational study is to learn about the relationship between stress urinary incontinence and endogenous steroids in women, especially its occurrence and severity with androgens and estrogens.
- Trial name
- NCT06109623
- Testing
- observation, sex hormone
- Volunteers
- 1,226 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital