Clinical trials: sponsored by RenJi Hospital
the Dynamic Evolution of Endometrial Carcinogenesis, Multiomics Analysis
A Multiomics Study Based on the Dynamic Evolution of Endometrial Carcinogenesis
The goal of this observational study is to draw the characteristic maps of imaging omics, genomics, transcriptome, proteomics, pathological omics, metabolomics, etc.
- Trial name
- NCT06007300
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Colonoscopy, Intestinal Disease
Mental Stress and Bowel Preparation Quality
The goal of this cross-sectional study was to explore the relationship between physical and psychological stress and the quality of bowel preparation before a colonoscopy examination, in order to improve the quality of bowel…
- Trial name
- NCT06007313
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
Bladder Cancer
[68Ga] NOTA-SGC8 in the Staging of Bladder Cancer
The goal of this clinical trial is to test the imaging and diagnostic ability of [68Ga]-NOTA-SGC8 PET/MR in bladder cancer patients with different stages.
- Trial name
- NCT06005116
- Testing
- [68Ga]-NOTA-SGC8
- Where
- China
- Volunteers
- 64 people
- Sponsor
- RenJi Hospital
Dexmedetomidine, Liver Transplantation, Allograft Function, Survival
Dexmedetomidine and Liver Transplantation
1.1. Background 1.1.1. Perioperative ischaemia/reperfusion (I/R) injury during liver transplantation is strongly associated with early allograft dysfunction, graft loss, and mortality. 1.1.2.
- Trial name
- NCT03770130
- Testing
- Dexmedetomidine, Saline
- Where
- China
- Volunteers
- 330 people
- Sponsor
- RenJi Hospital
Peripheral Arterial Disease
Predictive Value of the Global Limb Anatomic Staging System (GLASS) in Patients With Critical Limb-threatening Ischemia
The Global Vascular Guideline on chronic limb threatening ischemia (CLTI) proposes the Global Limb Anatomic Staging System (GLASS), a new angiographic scoring system to quantify the anatomic severity of infrainguinal disease in…
- Trial name
- NCT05999669
- Testing
- GLASS staging
- Volunteers
- 2,000 people
- Sponsor
- RenJi Hospital
To Evaluate the Clearance Rate of Uremic Toxin by HFR
Hemodiafiltration With Endogenous Reinfusion on Uremic Toxins Clearance of Maintenance Hemodialysis Patients
1.1Primary Objective To evaluate the clearance rate of uremic toxin β2-microglobulin (β2-MG), indoxyl sulfate and λ-free light chain (λFLC) by HFR.
- Trial name
- NCT06002529
- Testing
- HFR
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Gastric Cancer, Gastric Ulcer
Dose Exploration of Ciprofol for Sedation in Gastrointestinal Endoscopic Diagnosis and Treatment of Obese Patients.
Ciprofol is a new anesthetic, which combines with γ- Aminobutyric acid-a (GABAA) receptor. Ciprofol has shown equivalent anesthetic efficacy of propofol at 1/4 to 1/5 of the dosage.
- Conditions
- Gastric Cancer, Gastric Ulcer, Intestinal Polyps, Intestinal Cancer
- Trial name
- NCT05517408
- Testing
- ciprofol
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
68Ga-FAPI, Ovarian Cancer
Clinical Application of 68Ga-FAPI PET Imaging in Detection of Ovarian Cancer Recurrence
This is a prospective study to investigate the potential efficacy of 68Ga-FAPI PET/CT for recurrence detection of epithelial ovarian cancer in comparison with 18F-FDG PET/CT.
- Conditions
- 68Ga-FAPI, Ovarian Cancer, Epithelial Ovarian Cancer, Positron Emission Tomography
- Trial name
- NCT05856409
- Testing
- 68Ga-FAPI
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Rare Gynecological Tumors, Multi-omics Analysis
Prospective Multi-omics Observational Study of Gynecological Rare Pathological Tumors
The goal of this observational study is to draw the characteristic maps of genomics, transcriptome, proteomics, metabolomics, etc. in 600 patients with gynecological rare pathological types of malignant tumors.
- Trial name
- NCT05985941
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Bladder Cancer
Influence of Anesthesia Methods on CTCs in TURBT Patients
Multiple lines of evidence have shown that anesthesia method is associated with long-term outcomes in patients undergoing surgery due to cancers, including lung, breast, prostate, and bladder cancer, etc.
- Trial name
- NCT05824299
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- China
- Volunteers
- 162 people
- Sponsor
- RenJi Hospital
Liver Transplant Disorder, Hepatic Cancer
Liver Transplantation With Two-stage Liver Resection in Unresectable Liver Cancer , Metastases or Emd-stage Liver Disease (LTLR-LC)
Colon cancer and primary liver cancer are common malignant tumors with low survival rate worldwide, and unresectable primary liver cancer and colon cancer liver metastases have worse prognosis.
- Conditions
- Liver Transplant Disorder, Hepatic Cancer, End-stage Liver Disease
- Trial name
- NCT05750329
- Testing
- assisted liver transplantation combined with two-stage hepatectomy
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma, Molecular Targeted Therapy
Lenvatinib Combined With Gefitinib in the Treatment of Lenvatinib-resistant Hepatocellular Carcinoma
This is a prospective clinical study aiming to tests the safety and efficacy of lenvatinib in combination with gefitinib in people with lenvatinib resistant hepatocellular carcinoma.
- Trial name
- NCT04642547
- Testing
- Lenvatinib and Gefitinib
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
COVID-19
Brain Function Changes Following COVID-19 Infection
The global COVID-19 pandemic has now led to millions of infections worldwide. It produces long-lasting changes in the general physiology of multiple organs, including the brain.
- Trial name
- NCT05961618
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Prostate Cancer
Lidocaine Combined With Sufentanil for Preventing Catheter-related Bladder Discomfort
The goal of this clinical trial is to evaluate the incidence and severity of postoperative catheter-related bladder discomfort after robot-assisted radical prostatectomy.
- Trial name
- NCT05957653
- Testing
- lidocaine and sufentanil, Saline
- Volunteers
- 140 people
- Sponsor
- RenJi Hospital
Peritoneal Dialysis Solution Adverse Reaction
The Difference Between Daily and Alternative Day Use of Icodextrin
Volume overload is an important cause of technical failure in peritoneal dialysis patients. Icodextrin can provide continuous ultrafiltration, which provides a new option for peritoneal dialysis patients.
- Trial name
- NCT05943470
- Testing
- Icodextrin Peritoneal Dialysis Solution
- Volunteers
- 74 people
- Sponsor
- RenJi Hospital
Chemotherapy-Induced Thrombocytopenia
Hetrombopag for the Treatment of Chemotherapy-Induced Thrombocytopenia(CIT) in Patients With Acute Myeloid Leukemia
Randomized, controlled, open study to evaluate the efficacy and safety of Hetrombopag in the treatment of chemotherapy-induced thrombocytopenia(CIT) in patients with acute myeloid leukemia
- Trial name
- H-CIT-AML (NCT05944211)
- Testing
- Hetrombopag Olamine
- Volunteers
- 72 people
- Sponsor
- RenJi Hospital
Cardiovascular Diseases
Shanghai Community Cohort Establishment and Follow-up
Our objective is to establish a natural population cohort in East China based on the latest scientific researches, preliminary findings of the project team, and a close cooperation model of the Specialist Medical Consortium.
- Trial name
- NCT04517513
- Where
- China
- Volunteers
- 80,000 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma
GPC3-directed CAR-T in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma
This is a single arm, open-label, dose escalation clinical study to evaluate the safety and efficacy of infused autologous armored GPC3-directed CAR-T in patients with advanced hepatocellular carcinoma refractory to prior…
- Trial name
- NCT05926726
- Testing
- CAR-GPC3 T cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- RenJi Hospital
Liver Fibrosis
Multiomics Study of Fibrosis Factors After Liver Transplantation and Exploration of Fibrosis Methylation Biomarkers
This is a retrospective observational study in liver transplantation recipients with or without allograft liver fibrosis. Based on the GM-seq and Tcr-Seq data, a novel diagnostic model including DNA-methylation and TCR-Seq…
- Trial name
- NCT05926778
- Testing
- Liver allograft fibrosis
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Cerebral Small Vessel Diseases, Covert Postoperative Stroke
Cerebral Small Vessel Disease and Perioperative Covert Stroke
MOCSS study is a multicenter prospective clinical cohort study. The purpose of the MOCSS study is to investigate whether there is a correlation between the preoperative cerebral small vessel disease and the incidence of covert…
- Trial name
- MOCSS (NCT04443933)
- Where
- China
- Volunteers
- 548 people
- Sponsor
- RenJi Hospital