Clinical trials: sponsored by RenJi Hospital
Biliary Tract Diseases, Gallbladder Cancer
The Construction of Clinical Database and Multiomics Biobank Based on a Multicentral Prospective Cohort of Benign and Malignant Biliary Tract Diseases
The aim of the study is to establishing a standardized biobank and a clinical information database for patients with benign and malignant tumors of the biliary system.
- Conditions
- Biliary Tract Diseases, Gallbladder Cancer, Extrahepatic Bile Duct Cancer, Intrahepatic Cholangiocarcinoma
- Trial name
- NCT05896956
- Testing
- no interventions
- Volunteers
- 500 people
- Sponsor
- RenJi Hospital
Peripheral Arterial Disease
Smart Flex Stent System for the Treatment Long Femoropopliteal Artery Lesions
This study aims to evaluate the effectiveness and safety of the Smart flex stent system in treating long femoropopliteal native lesions.
- Trial name
- NCT05894863
- Testing
- Smart flex stent
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Cardiomyopathy With Unknown Etiology
Risk Stratification of Heart Failure in Cardiomyopathies.
The investigators aimed to use CMR technique in helping diagnose the etiology of unknown cardiomyopathy. Try to make a risk stratification of susceptible heart failure based on the extent of myocardial impairment.
- Trial name
- EARLY-MYO-HF (NCT02941315)
- Testing
- etiologic treatment,anti-myocardial remodeling, anti-myocardial remodeling, anti-myocardial remodeling,anti-acute heart failure
- Where
- China
- Volunteers
- 150 people
- Sponsor
- RenJi Hospital
ST Segment Elevation Myocardial Infarction, Left Ventricular Thrombus
Treatment of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant
Left ventricular thrombus is a common complication subsequent to ST-segment elevation myocardial infarction (STEMI) that related to increased embolic events.
- Trial name
- EARLYmyo-LVT (NCT03764241)
- Testing
- Rivaroxaban, Vitamin K Antagonist
- Where
- China
- Volunteers
- 280 people
- Sponsor
- RenJi Hospital
ST Segment Elevated Myocardial Infarction
Early rhBNP on Myocardial Remodeling and Reperfusion in Patients With STEMI
The study intends to evaluate the efficacy of early rhBNP on myocardial remodeling and reperfusion in patients with ST-segment elevation myocardial infarction after percutaneous coronary intervention
- Trial name
- NCT04033861
- Testing
- rhBNP, Control
- Where
- China
- Volunteers
- 352 people
- Sponsor
- RenJi Hospital
Breast Cancer, Chemotherapy Induced Systolic Dysfunction
Early Detection of CMP in Patients With Breast Cancer Using Cardiac Magnetic Resonance
Breast cancer is the most common cancers among women worldwide.Although chemotherapy and surgery have greatly improved the survival rate, most types of chemotherapy have been reported to have varying degrees of cardiotoxicity.
- Trial name
- NCT04510532
- Testing
- CMR examination
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Obese
EARLY Assessment of MYOcardial Tissue Characteristics in OBESITY (EARLY-MYO-OBESITY)
EARLY-MYO-OBESITY-CMR is a prospective, three-center, cardiac imaging study to investigate cardiac morphology, function, and tissue phenotypes in a cohort of non-diabetic obese adults, and compare with metabolically healthy…
- Trial name
- NCT05277779
- Testing
- cardiac magnetic resonance(CMR)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Myoma of Uterus, Colon Cancer
Anxiety Before Non-cardiac Surgery in Adults
Adult patients undergoing elective non-cardiac surgery were enrolled. Anxiety before the operation was evaluated by The State Anxiety Inventory (S-AI).
- Conditions
- Myoma of Uterus, Colon Cancer, Gastric Carcinoma, Prostate Cancer
- Trial name
- NCT05596188
- Where
- China
- Volunteers
- 424 people
- Sponsor
- RenJi Hospital
Hemodialysis Complication
A Study of Compound Amino Acid Capsule on Maintenance Hemodialysis Patients
The goal of this retrospective cohort study is to investigate the effects of compound amino acid capsule on nutrition, calcium and phosphorus metabolism in maintenance hemodialysis(MHD) patients.
- Trial name
- NCT05874557
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Peripheral Arterial Disease
Atherectomy Followed With a Drug Coated Balloon in the Treatment of Long Femoropopliteal Lesions
The study is a prospective, multicenter, randomized pilot study to evaluate the clinical outcome of the plaque atherectomy system followed by the UltrafreeTM drug coated balloon catheter versus the drug coated balloon in patients…
- Trial name
- NCT05868564
- Testing
- Atherectomy+Drug-coated balloon, Drug-coated balloon
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Metformin, Obesity, Abdominal
Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus
The purpose of this study is to analyze the effects of GLP-1RA on blood glucose, body weight, glucose and lipid metabolism and fat distribution in overweight/obese patients with type 2 diabetes mellitus.
- Conditions
- Metformin, Obesity, Abdominal, Diabetes Mellitus, Type 2, Abdominal Fat
- Trial name
- NCT05779644
- Testing
- Liraglutide, Semaglutide, Metformin
- Where
- China
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Breast Cancer
CDK4/6 Inhibitors in Patients With Hormone Receptor-positive Advanced Breast Cancer
This is an ambispective, single-center study to evaluate the survival outcomes, adverse events and predictive biomarkers for CDK4/6 inhibitors in patients with hormone receptor-positive advanced breast cancer.
- Trial name
- NCT05795335
- Testing
- CDK4/6 inhibitor
- Where
- China
- Volunteers
- 172 people
- Sponsor
- RenJi Hospital
Prostate Cancer
Multicenter, Prospective Clinical Study of the Serum Raman Spectroscopy Intelligent System for the Diagnosis of Prostate Cancer
At present, the most commonly used clinical screening tool is based on prostate-specific antigen (PSA) examination. Because PSA is a tissue-specific rather than a tumor-specific marker, it has low specificity and sensitivity for…
- Trial name
- NCT05854940
- Testing
- Serum Raman spectroscopy intelligent diagnostic system
- Where
- China
- Volunteers
- 490 people
- Sponsor
- RenJi Hospital
Lung Neoplasms
Attenuation of the Hemodynamic Response to Double-lumen Endotracheal Intubation With Nebulized Lidocaine
The goal of this clinical trial is to test the effect of nebulized lidocaine on the hemodynamic response in the participant undergoing double-lumen endotracheal intubation.
- Trial name
- NCT05850702
- Testing
- Lidocaine, Saline
- Volunteers
- 92 people
- Sponsor
- RenJi Hospital
Brain Injury Traumatic Severe, Intracranial Hemorrhage, Hypertensive
Multiomic Analysis of Traumatic Brain Injury and Hypertension Intracranial Hemorrhage Lesion Tissue
The goal of this experimental observation study is to figure out differently expressed biomarkers in lesion tissues in traumatic brain injury or hypertension intracranial hemorrhage patients.
- Trial name
- MOSS-THINK (NCT05778110)
- Testing
- Type of disease
- Where
- China
- Volunteers
- 10 people
- Sponsor
- RenJi Hospital
Brain Injuries, Traumatic
Multiomic Analysis of Body Fluid in Acute Traumatic Brain Injury
The goal of this experimental observation study is to figure out differently expressed biomarkers in body fluid in traumatic brain injury patients.
- Trial name
- MOSS-FAST (NCT05778123)
- Testing
- Type of disease
- Where
- China
- Volunteers
- 10 people
- Sponsor
- RenJi Hospital
Symptom Cluster, Symptoms and Signs
Construction of Symptom Network in Maintenance Hemodialysis Patients
Through a cross-sectional questionnaire survey, a general information questionnaire and Dialysis Frequency, Severity, and Symptom Burden Index were used to investigate the frequency, severity, and degree of symptom distress in…
- Conditions
- Symptom Cluster, Symptoms and Signs, Hemodialysis Complication, Hemodialysis-Associated Pruritus
- Trial name
- NCT05837988
- Where
- China
- Volunteers
- 517 people
- Sponsor
- RenJi Hospital
Metastatic Renal Cell Carcinoma
Application Circulating Tumor DNA Dynamic Monitoring in Clinical Treatment of Metastatic Renal Cell Carcinoma
Next-Generation Sequencing and whole transcriptome RNA sequencing were used to detect genomic variation and expression in tissues or blood, respectively.
- Trial name
- NCT05816642
- Testing
- sunitinib or pazopanib, PD-1 inhibitor combined with axitinib
- Where
- China
- Volunteers
- 500 people
- Sponsor
- RenJi Hospital
Third-line Treatment, Dvanced Duodenal Adenocarcinoma
Clinical Study on Third-line Treatment of Advanced Duodenal Adenocarcinoma by Fuquinitinib Combined With Sindillimab
This research project is a single-center, retrospective clinical exploration study. It aims to retrospectively analyze data from 20 patients with advanced duodenal adenocarcinoma who received third-line treatment with…
- Conditions
- Third-line Treatment, Dvanced Duodenal Adenocarcinoma, Furquinelone Combined With Sintilimab
- Trial name
- NCT05810142
- Testing
- furquimatinib and sintilimab
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Gout Tophus
A Exploratory Trial of WTX221 in Refractory Gout Patients
This trial is a single-center, open-label designed investigator-initiated clinical study (IIT) to investigate the safety, tolerability, PK, PD, immunogenicity, and preliminary efficacy of multiple doses of WTX221 infusion…
- Trial name
- NCT05800041
- Testing
- WTX221
- Volunteers
- 7 people
- Sponsor
- RenJi Hospital