Clinical trials: sponsored by RenJi Hospital
Gout Tophus
A Exploratory Trial of WTX221 in Refractory Gout Patients
This trial is a single-center, open-label designed investigator-initiated clinical study (IIT) to investigate the safety, tolerability, PK, PD, immunogenicity, and preliminary efficacy of multiple doses of WTX221 infusion…
- Trial name
- NCT05800041
- Testing
- WTX221
- Volunteers
- 7 people
- Sponsor
- RenJi Hospital
Neoadjuvant Therapy of Non-metastatic Locally Advanced Renal Cell Carcinoma
Toripalimab Combined With Axitinib as Neoadjuvant Therapy in Patients With Non-metastatic Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma
This study is design to prospectively investigate the safety and efficacy of Toripalimab combined with Axitinib in downsizing tumors in patients with nonmetastatic biopsy-proven clear cell renal cell carcinoma.
- Trial name
- NCT04118855
- Testing
- Toripalimab, Axitinib
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Intestines Cancer, Pulmonary Cancer
A Retrospective Cohort Study for Main Postoperative Complications After SARS-CoV-2 Infection
To explore the relationship between SARS-CoV-2 infection in different time before operation and postoperative main complications (mortality, main pulmonary and cardiovascular complications) 30 days after operation; To determine…
- Conditions
- Intestines Cancer, Pulmonary Cancer, Liver Cancer, Trauma
- Trial name
- NCT05781581
- Testing
- no intervention
- Volunteers
- 50,000 people
- Sponsor
- RenJi Hospital
Stroke, Ischemic
Safety and Efficacy of Therapeutic Hypothermia in Acute Ischemic Stroke
Therapeutic hypothermia (TH) in stroke has demonstrated robust neuroprotection in animals especially after ischemia-reperfusion injury, but its safety and efficacy remain controversial.
- Trial name
- THIS (NCT05779176)
- Testing
- Therapeutic hypothermia
- Where
- China
- Volunteers
- 252 people
- Sponsor
- RenJi Hospital
Serplulimab,Gastric Cancer, Adjuvant Therapy
A Study to Evaluate Serplulimab in Combination With Docetaxel +S-1 VS. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer
To evaluate the efficacy and safety of Serplulimab in Combination With Docetaxel +S-1 vs. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer (PD-L1 + / MSI-H / EBV +/dMMR) .
- Trial name
- NCT05769725
- Testing
- Serplulimab, Docetaxel, S1
- Where
- China
- Volunteers
- 70 people
- Sponsor
- RenJi Hospital
Sleep Disorder, Lung Tumor
Effect of Sleep Disorder on the Development of Lung Tumors
The goal of this observational study is to observe the lung tumor development in lung tumor patients with long-term sleep disorder.
- Trial name
- NCT05745506
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Solid Tumor
Exploratory Clinical Study of Autologous Tumor-infiltrating Lymphocyte Injection (GT201) for Advanced Gynecologic Tumors
This study is a single-center, single-arm phase I clinical trial. A total of 24~26 subjects (20 evaluable cases are expected) from 1 cohort will be enrolled in this study.
- Trial name
- NCT05724732
- Testing
- GT201
- Where
- China
- Volunteers
- 24 people
- Sponsor
- RenJi Hospital
Hypoglycemia
Analysis of Related Risk Factors of Hypoglycemia Consciousness Disorder
Objective to explore the high risk factors and inducements of consciousness disorder in patients with hypoglycemia, and to conduct a retrospective study.
- Trial name
- NCT04971070
- Testing
- Observation and follow-up
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Chongqing Renji Hospital, University of Chinese Academy of Sciences
Multiple Myeloma
PVd Versus Vd in NDMM Patients With RI
This is a multicenter, randomized controlled, open-label study, and the purpose of this study is to compare the efficiency and safety of PVD regimen (Pomalidomide \& Bortezomib \& Dexamethasone) versus VD regimen (Bortezomib \&…
- Trial name
- NCT05432414
- Testing
- pomalidomide, Bortezomib, Dexamethasone
- Where
- China
- Volunteers
- 79 people
- Sponsor
- RenJi Hospital
Intestines Cancer, Pulmonary Cancer
Main Postoperative Complications After COVID-19
To explore the relationship between SARS-CoV-2 infection in different time before operation and postoperative main complications (mortality, main pulmonary and cardiovascular complications) 30 days after operation; To determine…
- Conditions
- Intestines Cancer, Pulmonary Cancer, Liver Cancer, Trauma
- Trial name
- NCT05694949
- Volunteers
- 100,000 people
- Sponsor
- RenJi Hospital
Public Health
Shanghai Pudong Cohort
This is a community-based, prospective longitudinal epidemiologic study. Our objective is to establish a natural population-based cohort in Shanghai, China based on the latest scientific researches, preliminary findings of the…
- Trial name
- NCT05206643
- Where
- China
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Liver Transplantation
A New Prediction Mode for Predicting the Risk of Pressure Injury in Patients Undergoing Liver Transplantation
Pediatric population is at a high-risk of pressure injury (PI). Patients undergoing liver transplantation are more prone to PIs compared with other types of surgery.
- Trial name
- PMPRPIULT (NCT05588271)
- Testing
- Exposures
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Myocardial Bridge, Somatic Symptom Disorder
Somatic Symptom Disorders in Patients With Myocardial Bridge
The purpose of this study was to investigate the prevalence of physical and mental disorder in the population of patients with myocardial bridge and to describe the relationship between clinical features and the occurrence of…
- Trial name
- NCT04664387
- Testing
- coronary angiography
- Where
- China
- Volunteers
- 1,357 people
- Sponsor
- RenJi Hospital
Hypertrophic Cardiomyopathy, Hypertensive Heart Disease
Differentiation HHD From HCM (EARLY-MYO-HHD)
Differentiating hypertrophic cardiomyopathy (HCM) from hypertensive heart disease (HHD) unavoidably encounters diagnostic challenges especially in patient of suspected HCM with history of hypertension.
- Trial name
- NCT03271385
- Testing
- evaluated by the predetermined differentiating formula
- Where
- China
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Breast Cancer
A Pilot Study to Evaluate the Impact of Dexmedetomidine on Breast Cancer Recurrence After Surgery
Dexmedetomidine is widely used as an anaesthetic for general anesthesia during surgery. Previous studies in cells and animals show that dexmedetomidine may promote cancer growth.
- Trial name
- NCT03109990
- Testing
- Dexmedetomidine, Saline
- Where
- China
- Volunteers
- 148 people
- Sponsor
- RenJi Hospital
End Stage Renal Disease on Dialysis
AQP-1 Polymorphism on Fluid Status in Hemodialysis Patients
It is a cross sectional observational study. It is to investigate whether AQP-1 polymorphism has any impact on fluid status in hemodialysis patients.
- Trial name
- NCT05275387
- Testing
- observational study, no intervention
- Where
- China
- Volunteers
- 250 people
- Sponsor
- RenJi Hospital
Postoperative Cognitive Dysfunction, Postoperative Delirium
Neuroimaging Combining Biomarkers for Identifying Long-term Cognitive Dysfunction and Delirium
Postoperative Cognitive Dysfunction(POCD) is commonly seen in cardiac surgery, which may lead to poor pognosis. Cerebral small vessel disease(CVSD) is refer as the main resource of delirium among elderly people.
- Conditions
- Postoperative Cognitive Dysfunction, Postoperative Delirium, Cerebral Small Vessel Diseases, Covert Postoperative Stroke
- Trial name
- NeuroIDEA (NCT05594966)
- Testing
- multimodal MRI
- Where
- China
- Volunteers
- 211 people
- Sponsor
- RenJi Hospital
Herpes Zoster, Recombinant Zoster Vaccine
Recombinant Zoster Vaccine in Stable SLE Patients
The risk of herpers zoster reactivation is higher in SLE patients than general population. It has shown that mild or even inactive patients could also have varicella zoster virus (VZV) infections, and they account for about…
- Conditions
- Herpes Zoster, Recombinant Zoster Vaccine, Systemic Lupus Erythematosus
- Trial name
- NCT04516408
- Testing
- Recombinant zoster vaccine
- Where
- China
- Volunteers
- 464 people
- Sponsor
- RenJi Hospital
Inflammation Vascular
Glycemic Control on Coronary Inflammation Evaluated by FAI in ACS
This study aimed to clarify the relationship between blood glucose control and the FAI based pericoronary inflammation in low-risk ACS patients with or without diabetes.
- Trial name
- NCT05590858
- Where
- China
- Volunteers
- 309 people
- Sponsor
- RenJi Hospital
Whether Belimumab Could Reduce 2-year Risk of New-onset Lupus Nephritis
Belimumab In Prevention of LN
Systemic lupus erythematosus is a chronic autoimmune disease, which can involve multiple systems and largely impair patients' health. Kidney is the one of the most commonly affected organs.
- Trial name
- NCT05585671
- Testing
- Belimumab
- Volunteers
- 48 people
- Sponsor
- RenJi Hospital