Clinical trials: sponsored by RenJi Hospital
Connective Tissue Diseases, Right Ventricular Hypertrophy
Early Detection of Cardiac Impairment and Prediction of RV Hypertrophy in Patients With CTD
There have been reports suggesting that progressive RV failure and death in connective tissue disease (CTD) are related to right ventricular hypertrophy (RVH) and dilation, irrespective of pulmonary arterial hypertension (PAH).
- Trial name
- EARLY-MYO-CTD (NCT04297371)
- Testing
- CMR examination
- Where
- China
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Atrial Fibrillation, Atrial Flutter
EARLY-MYO-AF Registry
The purpose of this registry is to depict the myocardial function improvement in AF patients by integrated therapy and to assess the prognostic discrepancies of various intervention modalities.
- Trial name
- NCT04512222
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- RenJi Hospital
Liver Transplant; Complications, Hepatocellular Carcinoma Recurrent
Pembrolizumab and LENvatinib in Participants With Hepatocellular Carcinoma (HCC) Before Liver Transplant
Objectives of Study：This study will evaluate the safety and efficacy of pembrolizumab in combination with lenvatinib as neoadjuvant therapy in participants with hepatocellular carcinoma (HCC) exceeding Milan criteria before liver…
- Trial name
- PLENTY202001 (NCT04425226)
- Testing
- Pembrolizumab Injection [Keytruda], Lenvatinib Oral Product
- Where
- China
- Volunteers
- 192 people
- Sponsor
- RenJi Hospital
Advanced Esophageal Squamous Cell Cancer
Neoadjuvant Chemoradiotherapy Combined With Perioperative Toripalimab in Locally Advanced Esophageal Cancer
Neoadjuvant chemoradiotherapy (CRT) followed by surgery has become the standard treatment option for locally advanced esophageal squamous cell cancer (ESCC).
- Trial name
- NCT04437212
- Testing
- Toripalimab
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
ST-segment Elevation Myocardial Infarction (STEMI)
EARLY-MYO-CMR Registry
The purpose of this registry is to depict the myocardial tissue characteristics in STEMI patients by CMR and other cardiac imaging modalities and to assess the prognostic value of imaging-derived indices.
- Trial name
- NCT03768453
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
Multiple Synchronous Lung Cancers (MSLCs)
Prospective Genomics Initiative on Multiple Synchronous Lung Cancer (PGI-MSLC)
This prospective study is to characterize the genomic landscape and genetic heterogeneity of multiple synchronous lung cancer (MSLC) in correlation with comprehensive clinical, histopathological and medical imaging information…
- Trial name
- NCT03795155
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Transfusion Related Complication
Effects of Packed Red Blood Cell Storage Duration on Pediatric Living Donor Liver Transplantation
The patients assigned to either short-storage leukoreduced RBCs group (stored for ≤ 14 days) or longer-term storage leukoreduced RBCs group(stored for ≥21 days).When the hemoglobin concentration fell below 7.0 g per deciliter…
- Trial name
- NCT04413721
- Testing
- RBC transfustion
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Covid19, Echocardiography
Echocardiographic Manifestation in Patient With COVID-19 （EARLY-MYO COVID-19）
The cardiovascular effects of coronavirus disease 2019 (COVID-19) are not yet fully known. We conducted a prospective and dynamic echocardiographic study to investigate the cardiac structural and functional changes in COVID-19…
- Trial name
- NCT04352842
- Testing
- Echocardiography
- Where
- China
- Volunteers
- 51 people
- Sponsor
- RenJi Hospital
Type 2 Diabetes Mellitus With Circulatory Complciation
Association of Carbamylated HDL and CAD in T2DM Patients
This is an observational cross-sectional study aimed at investigating the alterations of the carbamylated-HDL levels in T2DM patients, and comparing the concentration of carbamylated-HDL between the T2DM patients with CAD and…
- Trial name
- NCT04390711
- Testing
- High density lipoprotein isolation, detection and in-vitro study.
- Where
- China
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Hepatic Ischemic and Reperfusion Injury
Liver Protection of RIPC in Pediatric Living Donor Liver Transplantation
Remote ischemic preconditioning(RIPC) is emerging as an promising therapeutic paradigm to combat the detrimental impact of ischemic and reperfusion injury.
- Trial name
- RIPC-PLDT (NCT02830841)
- Testing
- remote ischemic preconditioning(RIPC)
- Where
- China
- Volunteers
- 208 people
- Sponsor
- RenJi Hospital
Gastric Cancer Stage III
A Study to Evaluate Camrelizumab in Combination With Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage III Gastric Cancer
To evaluate the efficacy and safety of Camrelizumab in Combination With Docetaxel +S-1 Sequenced by Camrelizumab+S-1 as Adjuvant Treatment Therapy in Stage III Gastric Cancer (PD-L1 + / MSI-H / EBV +/dMMR) .
- Trial name
- NCT04152889
- Testing
- Camrelizumab, S-1, Docetaxel
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Myocardial Infarction
Early Treatment of ARNI on Myocardial Remodeling and Progress
Myocardial remodeling following myocardial infarction (MI) is an important prognostic factor for heart function and adverse cardiovascular events, especially are intimately linked with heart failure.
- Trial name
- NCT04342351
- Testing
- sacubitril/valsartan, perindopril, Cardiopulmonary Exercise Test
- Where
- China
- Volunteers
- 280 people
- Sponsor
- RenJi Hospital
ST Segment Elevation Myocardial Infarction
Early Assessment of QFR in STEMI-II
The study intends to provide new data on whether the noval method using quantitative flow ratio could assess microvascular dysfunction based on the previous study EARLY-MYO-QFR-I.
- Trial name
- EARLYmyoQFR-II (NCT03910400)
- Testing
- Computation of quantitative flow ratio
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
ST Segment Elevation Myocardial Infarction
Early Prediction of QFR in STEMI-I
The study intends to provide important data on whether the noval method using quantitative flow ratio could predict microvascular dysfunction.
- Trial name
- EARLYmyo-QFR-I (NCT03780335)
- Testing
- Computation of quantitative flow ratio
- Volunteers
- 162 people
- Sponsor
- RenJi Hospital
ST Segment Elevation Myocardial Infarction
Early Prediction of QFR in STEMI-Pharmaco-invasice
The study intends to provide important data on whether the noval method using quantitative flow ratio could predict microvascular dysfunction.
- Trial name
- EARLYmyoQFR-PI (NCT04220736)
- Testing
- Computation of quantitative flow ratio
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Myocarditis
EARLY-MYO-Myocarditis Registry
The purpose of this registry is to depict the myocardial tissue characteristics in patients with myocarditis by CMR and other cardiac imaging modalities and to assess the prognostic value of imaging-derived indices.
- Trial name
- NCT04338113
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Meningioma
Effects of Scalp Nerve Block With Ropivacaine on Postoperative Recovery Quality
Patients undergoing elective meningeoma resection surgery will be randomly assigned to one of the following two groups. After anesthesia induction but before skull-pin insertion, one group will receive scalp nerve blocks with…
- Trial name
- NCT03648034
- Testing
- ropivacaine, saline
- Where
- China
- Volunteers
- 144 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma
Effects of Anesthetic Methods on Hepatic Cancer Cell Malignancy
Numerous studies found that anesthetic methods can influence the recurrence of tumor and the overall survival of patients after primary cancer surgery.
- Trial name
- NCT03594188
- Testing
- anesthetic methods
- Where
- China
- Volunteers
- 24 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma, Portal Vein Tumor Thrombus
Lenvatinib Following Liver Transplantation in Patients of Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
The aim of this study is to observe the efficacy and safety of lenvatinib in preventing recurrence of hepatocellular carcinoma patients with portal vein tumor thrombus after liver transplantation.
- Conditions
- Hepatocellular Carcinoma, Portal Vein Tumor Thrombus, Liver Transplantation
- Trial name
- LLTHVV (NCT04319484)
- Testing
- lenvatinib
- Volunteers
- 108 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma, Liver Transplantation
Relenvatinib in the Tatment of Recurrence of Hepatocellular Carcinoma After Liver Transplantation
The aim of this study is to evaluate the efficacy and safety of lenvatinib in the treatment of recurrence of hepatocellular carcinoma after liver transplantation.
- Trial name
- RRHCCLT (NCT04237740)
- Testing
- relenvatinib
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital