Clinical trials: sponsored by RenJi Hospital
Insertion Depth of Central Venous Catheter
Swan-Ganz CCOmbo V for Obtaining an Optimal Depth of Right Internal Jugular Venous Catheter
The investigators will perform a study to create formula for the optimal insertion depth of right internal jugular vein catheter.
- Trial name
- NCT03544151
- Testing
- Swan-Ganz Continuous Cardiac Output Thermodilutioon Cather (Swan-Ganz CCOmbo V)
- Where
- China
- Volunteers
- 105 people
- Sponsor
- RenJi Hospital
Invasive Ductal Breast Cancer, Tubular Breast Cancer
Trial of Adjuvant Chemotherapy in Breast Cancer Patients With Pathological Partial Response and Complete Response to Neoadjuvant Chemotherapy
This trial will compare the administration of 2 cycles of paclitaxel and cisplatin (DP) versus 4 cycles of CEF as adjuvant chemotherapy for the patients with locally advanced breast cancer and who were pathological partial…
- Conditions
- Invasive Ductal Breast Cancer, Tubular Breast Cancer, Mucinous Breast Cancer, Inflammatory Breast Cancer
- Trial name
- NCT02879513
- Testing
- Paclitaxel, Cisplatin, Epirubicin
- Where
- China
- Volunteers
- 290 people
- Sponsor
- RenJi Hospital
Pancreatic Cancer, Locally Advanced Pancreatic Caner
An Open-label, Multicenter, Prospective Study of Irreversible Electroporation (Nano Knife) Combined With Radiotherapy and Chemotherapy in Patients With Locally Advanced Pancreatic Cancer
This is an open-label, multicenter, prospective study of irreversible electroporation (nano knife) combined with radiotherapy and chemotherapy in patients with locally advanced pancreatic cancer.
- Trial name
- NCT04310553
- Testing
- Irreversible electroporation
- Where
- China
- Volunteers
- 240 people
- Sponsor
- RenJi Hospital
ST Segment Elevation Myocardial Infarction, Coronary Slow Flow Phenomenon
Efficacy of Intracoronary Infusion of Different Medicine in STEMI Patients With CSFP
The study intends to evaluate the efficacy of different medicine delivering by targeted perfusion catheter in coronary administration on coronary blood flow in STEMI patients with CSFP.
- Trial name
- NCT03296670
- Testing
- Alprostadil, Nitroglycerin
- Where
- China
- Volunteers
- 57 people
- Sponsor
- RenJi Hospital
Agitation
Butorphanol Mitigate Emergence Agitation in Patients Undergoing Functional Endoscopic Sinus Surgery
Emergence agitation is one of the common postoperative complications after functional endoscopic sinus surgery（FESS). The objective of present study is to explore the effectiveness of butorphanol in the alleviation of emergence…
- Trial name
- NCT03398759
- Testing
- Butorphanol
- Where
- China
- Volunteers
- 700 people
- Sponsor
- RenJi Hospital
Postoperative Cognitive Dysfunction
Preoperative Pain and POCD in Elderly Patients
The purpose of this study is to investigate whether preoperative pain is the risk factor of POCD in elder patients.
- Trial name
- NCT03393676
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Combizym, Bifidobacteri
The Clinical Study on Combizym and Bifidobacteri to Prevent the Recurrence of Colon Polyps
The study hypothesis is whether digestion enzyme(Combizym) and intestinal flora drugs(Bifidobacteria) can decease recurrence rate of colon polyps
- Conditions
- Combizym, Bifidobacteri, Colon Polyps
- Trial name
- NCT02097394
- Testing
- Combizym, Bifidobacteri, Combizym + Bifidobacteri
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Syndrome X
Hierarchical Treatment Based on Somatization Symptom Checklist
A comparative study is conducted on the patients with suspected coronary artery disease (CAD). The patient will undergo coronary angiography after a somatic symptom scale (SSS) survey is carried out combining with Patient Health…
- Trial name
- NCT02723903
- Testing
- Deanxit, Prozac, coronary artery disease treatment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Polyp of Gallbladder
The Role of Different Imaging Methods in the Diagnosis of Gallbladder Polyps
This prospective cohort study is designed to investigate and to compare the diagnostic performance of contrast-enhanced ultrasonography (CEUS) and multidetector computed tomography (CT) for gallbladder cholesterol polyps, adenoma…
- Trial name
- NCT02762227
- Testing
- Abdominal high resolution CT, Contrast-enhanced ultrasonography (CEUS), Cholecystectomy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- RenJi Hospital
Osteoarthritis, Femoral Head Necrosis
Donepezil Attenuate Postoperative Cognitive Dysfunction
Postoperative cognitive dysfunction (POCD) occurs mainly in aged patients. POCD may increase the mortality and morbidity. However, the mechanism of POCD is not clear yet and no effective therapy method was proved.
- Conditions
- Osteoarthritis, Femoral Head Necrosis, Rheumatoid Arthritis
- Trial name
- DAPOCD (NCT02927522)
- Testing
- Donepezil
- Where
- China
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Prostate Cancer, Carcinoma of the Rectum
Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium
Postoperative cognitive dysfunction (POCD) and postoperative delirium occurs mainly in aged patients. POCD and POD may increase the mortality and morbidity.
- Conditions
- Prostate Cancer, Carcinoma of the Rectum, Colon Cancer, Renal Carcinoma
- Trial name
- MAPOCD (NCT02928692)
- Testing
- Minocycline
- Where
- 5 sites in China
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Emergence Agitation
Dexmedetomidine and Propofol in the Treatment of Emergence Agitation
1. This clinical research aims to compare the effects of dexmedetomidine and propofol on the treatment of emergence agitation in adult patients after general anesthesia. 2.
- Trial name
- NCT04142840
- Testing
- Dexmedetomidine, Propofol
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Prostate Cancer, Chemotherapy Effect
Neoadjuvant Chemo-hormonal Therapy Combined With Radical Prostatectomy for Locally Advanced Prostate Cancer
To evaluate of the value of radical prostatectomy and extended pelvic lymph node dissection in locally advanced prostate cancer after neoadjuvant hormonal therapy with or without docetaxel chemotherapy.
- Conditions
- Prostate Cancer, Chemotherapy Effect, Hormone Sensitive Prostate Cancer, Locally Advanced Prostate Carcinoma
- Trial name
- NCT04220398
- Testing
- Neoadjuvant chemotherapy combined with hormone therapy, Neoadjuvant hormone therapy, Radical Prostatectomy (RP)+ extended lymph node dissection
- Volunteers
- 475 people
- Sponsor
- RenJi Hospital
Myocardial Injury, Connective Tissue Diseases
Effect of Sacubitril/Valsartan on Reduced Right Ventricular Ejection Fraction in Patients With CTD
Heart failure, one of the leading causes of connective tissue disease (CTD) mortality, has attracted increasing attention. Currently, no known study had focused on the effect of sacubitril/valsartan on right ventricular…
- Trial name
- EARLY-MYO-CTD (NCT04197050)
- Testing
- Sacubitril / Valsartan Oral Tablet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Gastric Cancer
Tripletrumab Combined With Oxaliplatin and Teggio (SOX) in First-line Treatment of Gastric and Gastroesophageal Junction Adenocarcinoma
The aim population is histopathologically confirmed locally unresectable advanced recurrent or metastatic adenocarcinoma of the gastric and gastroesophageal junction.
- Trial name
- NCT04202484
- Testing
- Toripalimab combined with oxaliplatin and Tegafur,Gimeracil and Oteracil Porassium Capsules
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Quality of Life
A Multicenter Randomized Controlled Study of the Effect of Laparoscopic Preservation of the Pylorus
For the patients with early gastric cancer (T1), preoperative evaluation (gastroscope, ultrasound gastroscope and abdominal enhanced CT) showed that the tumor was located in the body of the stomach, and the margin was enough to…
- Trial name
- NCT04164095
- Testing
- lappg
- Volunteers
- 160 people
- Sponsor
- RenJi Hospital
Diabetes Mellitus, Type 2
Effects of Artificial Sweeteners on Glucose Metabolism in Patients With Type 2 Diabetes
To investigate the effects of artificial sweeteners on glucose metabolism in newly diagnosed type 2 diabetic patients
- Trial name
- SWEETS (NCT04185662)
- Testing
- sucralose
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Multiple Primary Neoplasm
KN035 in Patients With Advanced Multiple Primary Tumors
This study is a prospective, single arm, single center exploratory clinical research, to evaluate KN035 late treatment in patients with Multiple Primary tumors (MPC, Multiple Primary working) clinical benefit.In the study, all…
- Trial name
- CPOG035-01 (NCT04182789)
- Testing
- KN035
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma
Lenvatinib Following Liver Transplantation in Patients With High-Risk Hepatocellular Carcinoma
The aim of this study is to observe the efficacy and safety of lenvatinib in preventing high-risk recurrence of hepatocellular carcinoma patients after liver transplantation.The cases are from patients with hepatocellular…
- Trial name
- NCT04168944
- Testing
- Lenvatinib, Immunosuppressive regimen
- Volunteers
- 108 people
- Sponsor
- RenJi Hospital
Gastric Cancer
A Real World Study of Laparoscopic Preservation of the Pylorus Gastrectomy
For the patients with early gastric cancer (T1), preoperative evaluation (gastroscope, ultrasound gastroscope and abdominal enhanced CT) showed that the tumor was located in the body of the stomach, and the margin was enough to…
- Trial name
- NCT04160962
- Testing
- lappg
- Volunteers
- 160 people
- Sponsor
- RenJi Hospital