Clinical trials: sponsored by RenJi Hospital
Total Hip Arthroplasty (THA), Femoral Neck Fractures
PNB Anesthesia Improves Older Patients' Postoperative Early Recovery Outcomes After Total Hip Arthroplasty
Early postoperative rehabilitation is an important issue for total hip arthroplasty, especially in older patients. This retrospective clinical trial is to assess the impact of peripheral nerve block anesthesia versus general…
- Trial name
- NCT07163598
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 516 people
- Sponsor
- RenJi Hospital
Pulmonary Hypertension
Continuous Effect Of Rehabilitation Training On Pulmonary Arterial Hypertension Patients
This multicenter, open label, double-arm study aims at investigating the the continuous effect of long-Term rehabilitation training on clinical improvement(ITTCI) and cardiopulmonary function in pulmonary arterial hypertension…
- Trial name
- NCT07149935
- Testing
- Rehabilitation Training
- Where
- China
- Volunteers
- 104 people
- Sponsor
- RenJi Hospital
Cancer Patients With Acute Lower Limb Deep Vein Thrombosis (DVT)
Mechanical Thrombectomy for Acute Lower Limb Deep Vein Thrombosis in Tumor Patients
This study will conduct a prospective single blind controlled study on the clinical efficacy and safety indicators of 50 cancer patients with acute lower limb deep vein thrombosis (DVT).
- Trial name
- NCT06085495
- Testing
- mechanical thrombectomy (PMT)
- Where
- China
- Volunteers
- 52 people
- Sponsor
- RenJi Hospital
Hip Dysplasia, Developmental
Diagnostic Efficacy Study of AI System in Screening Infants With Developmental Dysplasia of the Hip
To ascertain the efficacy of the DeepDDH system, a deep learning framework, in enhancing diagnostic accuracy and curtailing follow-up intervals for infants undergoing screening for developmental dysplasia of the hip (DDH), the…
- Trial name
- ASIDDH (NCT06803004)
- Testing
- Junior sonographer measurement of DDH, Senior sonographer measurement of DDH, Automated annotation of the DDH measurement through deep learning
- Where
- China
- Volunteers
- 1,789 people
- Sponsor
- RenJi Hospital
Bladder (Urothelial, Transitional Cell) Cancer
A Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin Combined With PD-1 Inhibitor and Radiotherapy as Bladder-preserving Therapy in Patients With Localized HER2-high Expressing Muscle-invasive Bladder Urothelial Carcinoma Following Maximal Transurethral Resection
This is a prospective, open label, multicenter clinical study of vediximab combined with PD-1 and radiation therapy for bladder preservation in MIBC patients with HER-2 high expression (IHC 2+or 3+), conducted in accordance with…
- Trial name
- DECIDING (NCT07142200)
- Testing
- Disitamab Vedotin, PD-1 inhibitor, radiotherapy
- Where
- China
- Volunteers
- 45 people
- Sponsor
- RenJi Hospital
Regional Anesthesia Morbidity, Pain, Postoperative
Randomized Trial of Erector Spinae Plane Block Using Liposomal Bupivacaine Versus Bupivacaine Hydrochloride on Quality of Recovery for Video-assisted Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) has emerged as the standard surgical modality for pulmonary tumor. Compared with open thoracotomy, VATS is associated with reduced surgical trauma, attenuated postoperative pain, and a…
- Trial name
- LB-ESPB (NCT07141667)
- Testing
- Erector spinae plane block with liposomal bupivacaine, Erector spinae plane block with bupivacaine HCL
- Volunteers
- 80 people
- Sponsor
- RenJi Hospital
Still Disease, Autoinflammatory Disease
Clinical Autoinflammatory Disease Cohort
Autoinflammatory diseases (AIDs) are a group of rare disorders caused by dysregulation of the innate immune system, characterized by recurrent fever, systemic inflammation, and involvement of specific organs.
- Trial name
- CAID (NCT07126145)
- Testing
- Not applicable- observational study
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
High-grade Glioma
Multi-Dimensional MRI Spatial Heterogeneity Analysis for Predicting Key Genes and Prognosis of High-Grade Gliomas: A Multi-Center Study
1. To retrospectively explore the feasibility of multi-dimensional heterogeneity imaging features of MRI in predicting the status of key gene mutations in high-grade gliomas; 2.
- Trial name
- NCT06002711
- Testing
- MR scanning; Clinical data collection
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- RenJi Hospital
Postoperative Delirium
EEG-TMS Intervening Against Postoperative Delirium
Postoperative delirium is common in elderly surgical patients and is associated with complications and prolonged hospitalisation.
- Trial name
- RECOVER (NCT07100197)
- Testing
- continuous Theta-burst stimulation
- Where
- China
- Volunteers
- 98 people
- Sponsor
- RenJi Hospital
Systemic Lupus Erythematosus (SLE), Immune-mediated Necrotizing Myopathy (IMNM)
A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy
This is an investigator-initiated, multicenter, open-label study of C-CAR168, an autologous bi-specific CAR-T therapy targeting CD20 and BCMA, for the treatment of adult patients with autoimmune diseases refractory to standard…
- Conditions
- Systemic Lupus Erythematosus (SLE), Immune-mediated Necrotizing Myopathy (IMNM), Neuromyelitis Optica Spectrum Disorders (NMOSD), Multiple Sclerosis (MS)
- Trial name
- CAR-AID (NCT06249438)
- Testing
- CD20/BCMA-directed CAR-T cells
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Uremia, End Stage Renal Disease on Dialysis
Independent Effects of Visceral Adipose Volume and Density on Patient Survival in Peritoneal Dialysis
It was VAT volume predict patient outcome, while VAT density predicted baseline membrane function in PD patients and reflected peritoneal vascular density and local inflammation status.
- Trial name
- NCT07086430
- Volunteers
- 358 people
- Sponsor
- RenJi Hospital
Stress Urinary Incontinence
Electroacupuncture and Pelvic Floor Muscle Training for Male Stress Urinary Incontinence
The goal of this clinical study is to compare the effects of combined electroacupuncture with pelvic floor muscle training (PFMT) versus PFMT alone in the treatment of involuntary urine leakage following prostate removal…
- Trial name
- NCT05773716
- Testing
- Pelvic floor muscle training, Electroacupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Gastrointestinal Endoscopy
Etomidate Combined With Propofol Versus Propofol for Sedation in High-Altitude Patients During Gastroscopy: a Randomized Multicenter Clinical Trial
One of the most common adverse events during sedated gastrointestinal endoscopy is hypoxemia, which can lead to serious consequences.
- Trial name
- NCT07079176
- Testing
- etomidate combined with propofol, propofol
- Volunteers
- 732 people
- Sponsor
- RenJi Hospital
Abdominal Aortic Aneurysm
REST4-AAA Registry
This prospective observational study aims to investigate whether serum REST4 concentration can serve as a quantitative indicator correlated with abdominal aortic aneurysm (AAA) diameter and a predictive biomarker for AAA…
- Trial name
- REST4 Registry (NCT07056491)
- Testing
- mRNA level of REST4 in serum;
- Where
- China
- Volunteers
- 70 people
- Sponsor
- RenJi Hospital
Acute Myocardial Infarction
The Effectiveness of a TTM-based Multidisciplinary Collaboration on Cardiac Rehabilitation Outcomes in Patients With AMI
Cardiac rehabilitation (CR) has been shown to reduce morbidity and mortality in patients with acute myocardial infarction (AMI), however, the proportion of patients participating in and benefiting from cardiac rehabilitation (CR)…
- Trial name
- NCT07045220
- Testing
- TTMCR
- Where
- China
- Volunteers
- 86 people
- Sponsor
- RenJi Hospital
Unresectable Hepatocellular Carcinoma
HAIC + Atezolizumab Plus Bevacizumab in Unresectable HCC
Patients with unresectable HCC will be enrolled in the cohort and will receive the combination therapy of HAIC and atezolizumab plus bevacizumab.
- Trial name
- NCT07045558
- Where
- China
- Volunteers
- 28 people
- Sponsor
- RenJi Hospital
Acute-On-Chronic Liver Failure, Chronic Liver Failure
Micro-encapsulated Hepatocyte Intraperitoneal Transplantation in Liver Failure Adults
This is a prospective single-center dose escalation study of the administration of the microencapsulated hepatocyte therapy in adult liver failure.
- Trial name
- NCT05727722
- Testing
- a single course of micro-encapsulated hepatocytes intraperitoneal transplantation therapy
- Where
- China
- Volunteers
- 10 people
- Sponsor
- RenJi Hospital
Abdominal Aortic Aneurysm, Image
AAA-CTA Cohort Registry
The aim of this study is to investigate the measurement of abdominal aortic aneurysm by computed tomography angiography. The research will collected the results of computed tomography angiography from inpatient, emergency, and…
- Trial name
- NCT07039825
- Testing
- Computed tomography angiography
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
Hypoxia, Gastric Polyp
The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure
Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing gastrointestinal endoscopy with propofol.
- Conditions
- Hypoxia, Gastric Polyp, Colon Cancer, Esophageal Cancer
- Trial name
- NCT06081647
- Testing
- the COMBO Endoscopy Oropharyngeal Airway, Regular Nasal Cannula
- Where
- 10 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Acute Pulmonary Embolism
Mechanical Thrombectomy for Acute Pulmonary Embolism
Research Objective: To prospectively compare the efficacy and safety of a pre-collaboratively developed ultra-thin PTFE minimally invasive thrombectomy system versus standard pharmacological therapy in patients with acute…
- Trial name
- NCT07032025
- Testing
- Innovative Device Group, Standard Pharmacological Therapy Group
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital