Clinical trials: sponsored by RenJi Hospital
Kidney Transplant
Clinical Study on Thymus-Kidney Transplantation From Neonatal Donors for the Induction of Immune Tolerance
Thymus transplantation for the induction of immune tolerance in kidney transplantation: This study aims to understand how thymus transplantation can induce immune tolerance in recipients of allogeneic kidney transplants to…
- Trial name
- NCT06715865
- Testing
- Thymus Transplantation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, Metformin
Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight/Obese PCOS Patients
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and is characterized by ovulatory dysfunction, increased androgens, and polycystic ovaries.
- Conditions
- Polycystic Ovary Syndrome, Metformin, Acupuncture
- Trial name
- NCT06717087
- Testing
- Acupuncture+lifestyle intervention, Metformin+lifestyle intervention
- Where
- China
- Volunteers
- 92 people
- Sponsor
- RenJi Hospital
Psychological Distress, Insomnia
A Multicenter Cross-sectional Study on Mental Health of Patients With Multiple Myeloma
Multiple myeloma patients with normal ability of communication and understanding will be enrolled. DT, GAD-7, PHQ-15 and PSQI scales are designed to assess the mental health status of the patients.
- Conditions
- Psychological Distress, Insomnia, Somatic Symptoms
- Trial name
- NCT05620420
- Where
- China
- Volunteers
- 501 people
- Sponsor
- RenJi Hospital
End Stage Renal Disease
Bioimpedance-guided Fluid Management in Chronic Peritoneal Dialysis Patients.
Peritoneal dialysis (PD) is one of established treatments in the end stage renal disease patients. Volume overload is a predictor of mortality in PD patients.
- Trial name
- NCT03004963
- Testing
- Body composition monitor, clinical indexes
- Where
- China
- Volunteers
- 213 people
- Sponsor
- RenJi Hospital
Postoperative Delirium
Treatment of Postoperative Delirium With Continuous Theta Burst Stimulation
To determine whether continuous theta burst stimulation can cure postoperative delirium in senior patients.
- Trial name
- NCT05239897
- Testing
- Continuous theta burst stimulation (cTBS)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Brain Injuries
Electroencephalography in the Management of Neuroelectric Stimulation in Patients With Severe Traumatic Brain Injuries
The goal of this observational retrospective study is to evaluate the electroencephalography (EEG)'s poficiency in the treatment of neuroelectric stimulation in patients with severe traumatic brain injuries (TBI).
- Trial name
- NCT06571032
- Where
- China
- Volunteers
- 50 people
- Sponsor
- RenJi Hospital
Cranial Defect, TCD
A Prospective Observational Study of Transcranial Doppler Ultrasound in the Assessment of Cerebral Blood Flow After Polyetheretherketone Cranioplasty
Polyetheretherketone has become one of the most important material choices for cranioplasty surgery. It has been shown that conventional ultrasound can be performed through the polyetheretherketone material for the examination of…
- Trial name
- NCT06642532
- Testing
- TCD group
- Where
- 2 sites in China
- Volunteers
- 10 people
- Sponsor
- RenJi Hospital
Myocardial Infarction
18F-PBR06/Total Body PET Imaging in Patients With STEMI
The study will use 18F-PBR06/uExplorer to study the activation of macrophages and systemic perfusion in patients with ST-segment elevation myocardial infarction (STEMI) or stable angina (SA).
- Trial name
- NCT05269446
- Testing
- percutaneous coronary intervention (PCI), total body PET/CT scan, Coronary Angiography (CAG)
- Where
- China
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Skull Defect
Prospective Observational Study on Comprehensive Effects of PEEK Cranioplasty and Titanium Cranioplasty After DC（RECEPT-DC）
The objective of this trial is to scientifically evaluate the efficacy of PEEK cranioplasty and titanium cranioplasty. The primary objective is to compare the rate of implant failure (defined as infection, implant exposure and…
- Trial name
- NCT05416684
- Where
- China
- Volunteers
- 358 people
- Sponsor
- RenJi Hospital
PCOS, Glucose Metabolism Disorder
Study of Time-restricted Eating (TRE) to Clinical Pregnancy Rate in PCOS Women With Glucose Metabolism Disorder Via IVF/ICSI
Investigate the effect and mechanism of time-restricted eating (TRE) on the clinical pregnancy rate in women with PCOS and glucose metabolism disorder via IVF/ ICSI.
- Conditions
- PCOS, Glucose Metabolism Disorder, IVF Outcome
- Trial name
- NCT06666933
- Testing
- Time restricted eating, Metformin
- Where
- China
- Volunteers
- 254 people
- Sponsor
- RenJi Hospital
Renal Cell Carcinoma, Clear Cell
A Multimodal Predictive Recurrence Score for Patients With Clear Cell Renal Cell Carcinoma
The main goal of this observational study is to construct a predictive recurrence model for renal clear cell carcinoma through an artificial intelligence multimodal algorithm, which will improve the prognosis and survival time of…
- Trial name
- NCT06656039
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- RenJi Hospital
Physical Examination
Study on the Safety and Efficacy of Sodium Phosphate Powder for Intestinal Preparation in People Aged 50 to 70 Years Old
Project Name: Safety and Efficacy of Sodium Phosphate Powder for Intestinal Preparation in People Aged 50 to 70: A Prospective, Multicenter, Randomized Controlled Clinical Trial The main purpose of the study is to investigate the…
- Trial name
- NCT06652906
- Testing
- Sodium phosphate powder, Polyethylene glycol electrolyte dispersion
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Diabetes, Renal Insufficiency, Chronic
PK and PD of YG1699 in CKD Patients With Diabetes
The goal of this clinical trial is to learn PK and PD of YG1699 in patients with diabetes and renal dysfuction. Participants will: Take YG1699 or a placebo every day for 8 days. Visit the clinic 7 times for checkups and tests.
- Conditions
- Diabetes, Renal Insufficiency, Chronic, Hemodialysis
- Trial name
- NCT06648876
- Testing
- YG1699
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Liver Cancer
DEB-TACE Prior to Liver Transplantation in the Treatment of HCC
The goal of the study is to explore whether the usage of DEB-TACE (Drug-Eluting Bead Transarterial Chemoembolization) prior to living donor liver transplantation can prolong the recurrence-free survival in patients with…
- Trial name
- NCT06353126
- Testing
- DEB-TACE
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Anticoagulation
Point-of-Care Testing (POCT) for Guided Precision Anticoagulation With Warfarin: A Multicenter, Non-concurrent Controlled Study
This study aims to compare the key clinical indicators such as the time to achieve INR target, frequency of dose adjustment, and the incidence of thrombotic and hemorrhagic events between Point-of-Care Testing (POCT) and…
- Trial name
- NCT06645275
- Testing
- POCT test
- Volunteers
- 416 people
- Sponsor
- RenJi Hospital
Hydrocephalus, Communicating
A Prospective Observational Study of Perioperative Lumbar Puncture Pressure and Shunt Valve Pressure Management in Patients with Communicating Hydrocephalus Undergoing Lumboperitoneal Shunt Surgery
Target population: patients 18 years of age or older who require surgical treatment with lumboperitoneal shunt surgery for traffic hydrocephalus Estimated sample size: 30 cases.
- Trial name
- LPP-LPS (NCT06642129)
- Testing
- surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Pancreatic Cancer, First-line
Anlotinib Plus Benmelstobart and AG in First-line Treatment of Advanced Metastatic Pancreatic Cancer (ALTER-PA-001)
This study is designed to explore the efficacy and safety of anlotinib combined with benmelstobart and AG (nab-paclitaxel and gemcitabine) as first-line treatment compared with AG (nab-paclitaxel and gemcitabine) in metastatic…
- Conditions
- Pancreatic Cancer, First-line, Metastatic Pancreatic Cancer
- Trial name
- NCT06621095
- Testing
- anlotinib + benmelstobart + nab-paclitaxel + gemcitabine, nab-paclitaxel + gemcitabine
- Where
- China
- Volunteers
- 104 people
- Sponsor
- RenJi Hospital
Atheroscleroses, Cerebral, Intracranial Atherosclerosis
Balloon-expandable DES for ICAS Registry Study (BDES-ICAS Registry)
To study the clinical outcomes after implantation of balloon-expandable drug-eluting stents in patients with symptomatic intracranial atherosclerotic stenosis in prevention of composite event of any stroke and death within 30…
- Conditions
- Atheroscleroses, Cerebral, Intracranial Atherosclerosis, Ischemia Stroke
- Trial name
- NCT06614972
- Testing
- Balloon-expandable drug-eluting stent
- Volunteers
- 520 people
- Sponsor
- RenJi Hospital
Hypoxia, Hysteroscopy
The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
Hypoxia is a common adverse event during sedated hysteroscopy for assisted reproduction, and it is more likely to occur in overweight or obese patients.
- Conditions
- Hypoxia, Hysteroscopy, Overweight or Obesity
- Trial name
- RP (NCT06187896)
- Testing
- remimazolam, Propofol
- Where
- China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Multiple Myeloma
Allogeneic Anti-BCMA/GPRC5D Bispecific CAR-NK Cells (ACT-001) in Patients With Relapsed or Refractorymultiple Myeloma
This is a single-arm, open-label, exploratory clinical study to evaluate the safety and efficacy of allogeneic anti-BCMA/GPRC5D bispecific chimeric antigen receptor natural killer (CAR-NK) cells (ACT-001) in patients with…
- Trial name
- NCT06594211
- Testing
- ACT-001 CAR-NK cell
- Where
- China
- Volunteers
- 18 people
- Sponsor
- RenJi Hospital