Clinical trials: sponsored by Research Inc
Vascular Inflammation, Psoriasis
Cytokines and Vascular Inflammation in Psoriasis
Psoriasis is an inflammatory disease involving the skin, the joints and the vascular compartment. The mechanisms linking inflammation in the skin and joints and in the vascular walls are poorly understood.
- Conditions
- Vascular Inflammation, Psoriasis, Coronary Atherosclerosis
- Trial name
- NCT02305953
- Where
- 4 sites in Canada
- Volunteers
- 96 people
- Sponsor
- Innovaderm Research Inc.
Cancer
A Trial of ALB 109564(a) in Subjects With Advanced Solid Tumors
The purpose of this study is to determine the maximum tolerated dose of ALB 109564(a), a novel tubulin inhibitor, and to assess safety, pharmacokinetics, and anti-tumor activity in subjects with advanced solid tumors.
- Trial name
- NCT00724100
- Testing
- ALB 109564(a) (12´-methylthiovinblastine dihydrochloride)
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Albany Molecular Research, Inc.
Psoriasis
Safety and Efficacy of Etanercept in Patients With Psoriasis Who Failed to Respond to Other Biologic Treatments
The purpose of this study is to evaluate safety and efficacy of etanercept in patients with psoriasis who had an unsatisfactory response to adalimumab and infliximab.
- Trial name
- NCT00967538
- Testing
- etanercept 50 mg
- Where
- 16 sites in Canada
- Volunteers
- 89 people
- Sponsor
- Innovaderm Research Inc.
Psoriatic Arthritis, Psoriasis
Exploratory Study on Quality of Life in Patient With Moderate Psoriasis and Moderate Psoriatic Arthritis
This exploratory study will be used to identify questions that will be part of a new QoL questionnaire for patients with psoriasis and psoriatic arthritis and to determine the sample size needed for its validation.
- Trial name
- NCT01139918
- Where
- 10 sites in Canada
- Volunteers
- 105 people
- Sponsor
- Innovaderm Research Inc.
Ultraviolet Rays, Immunosuppression
Effect of RANKL Inhibition on UV-induced Immunosuppression
Ultraviolet (UV) light is part of normal sunlight and has many effects on human skin and health. One of the harmful effects of long-term UV light exposure is that it can cause skin cancer.
- Conditions
- Ultraviolet Rays, Immunosuppression, Hypersensitivity, Delayed, Immune Tolerance/Drug Effects
- Trial name
- NCT01978483
- Testing
- Denosumab, UVB exposure, Diphenylcyclopropenone
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Chronic Hand Dermatitis
Pilot Study on the Use of Acitretin for the Treatment of Severe Chronic Hand Dermatitis
This pilot, phase II, 24-week study will recruit a total of 10 patients and will evaluate the efficacy and safety of acitretin in patients with severe chronic hand dermatitis .
- Trial name
- NCT01545284
- Testing
- Acitretin
- Where
- 2 sites in Canada
- Volunteers
- 9 people
- Sponsor
- Innovaderm Research Inc.
Focus on Physical Activity, Recess, and Play
Randomized Experiment of Playworks
The purpose of this study is to determine whether Playworks has an impact on student and school outcomes such as physical activity, behavior, and academic performance.
- Trial name
- NCT02192281
- Testing
- Playworks
- Where
- United States
- Volunteers
- 2,278 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Lung Neoplasms
Breath Test for Early Detection of Lung Cancer
To demonstrate and validate a breath test for detection of early stage lung cancer that could potentially reduce number of deaths.
- Trial name
- NCT00639067
- Testing
- Breath Collection Apparatus
- Where
- 4 sites in United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Menssana Research, Inc.
Soft Tissue Injuries, Gouty Arthritis
AMPED Outcomes Registry of Post-ED Pain Management
Study aims to assess patient-recorded outcomes of pain control medications prescribed in the ER after visits for specific painful injuries/illnesses.
- Conditions
- Soft Tissue Injuries, Gouty Arthritis, Fractures, Ureteral Colic
- Trial name
- AMPED (NCT01626235)
- Where
- 11 sites in United States
- Volunteers
- 843 people
- Sponsor
- Radnor Registry Research, Inc
Pigmentation From Visible Light
Vitamin E Prevention of Visible Light Pigmentation
The main objective of the study is to assess the efficacy of an antioxidant in preventing pigmentation induced by visible light in subjects with a phototype IV or V.
- Trial name
- NCT01927679
- Testing
- Vitamin E, Eucerin
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Interstitial Cystitis
Intranasal Ketorolac Tromethamine (Sprix) for Acute Pain of Interstitial Cystitis Flare of Pain
Intranasal Ketorolac tromethamine has a potential role as a short term pain management tool for Interstitial Cystitis without the risk and undesirable effects of narcotics.
- Trial name
- NCT02000401
- Testing
- Ketorolac Tromethamine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Citrus Valley Medical Research, Inc.
Post Vasectomy Pain
Intranasal Ketorolac Tromethamine (SPRIX) as a Short Term Pain Management of Post-Vasectomy Pain
To evaluate the efficacy, tolerability and safety of intranasal ketorolac tromethamine (SPRIX) as an option for pain management in post vasectomy patients.
- Trial name
- NCT02000388
- Testing
- Ketorolac Tromethamine, Standard of Care
- Volunteers
- 15 people
- Sponsor
- Citrus Valley Medical Research, Inc.
Epilepsy
A Study in Stable Epilepsy Patients Comparing Brand and Generic Divalproex Sodium Extended Release Tablets
A study in stable epilepsy patients comparing levels of valproic acid after administration of brand and generic divalproex sodium extended release tablets.
- Trial name
- Epilepsy (NCT01898676)
- Testing
- Divalproex Sodium Extended-release 250mg, DEPAKOTE 250mg
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Vince & Associates Clinical Research, Inc.
Palmo-Plantar Pustular Psoriasis, Palmo-Plantar Pustulosis
Safety and Efficacy of Ustekinumab in Patients With Palmo-Plantar Pustular Psoriasis or With Palmo-Plantar Pustulosis
This study will provide data on sasety and efficacy of Ustekinumab in patients suffering from Palmo-Plantar Pustular Psoriasis (PPPP) or Palmo-Plantar Pustulosis(PPP)
- Trial name
- NCT01091051
- Testing
- Ustekinumab
- Where
- 8 sites in Canada
- Volunteers
- 33 people
- Sponsor
- Innovaderm Research Inc.
Bipolar Depression
Bipolar Study of Seroquel XR With Pramipexole Dihydrochloride
This study is designed to assess the use of pramipexole dihydrochloride and quetiapine (Seroquel) XR as combination therapy for bipolar depression.
- Trial name
- NCT00893841
- Testing
- quetiapine (Seroquel) XR, pramipexole dihydrochloride
- Where
- 9 sites in United States, Canada
- Volunteers
- 96 people
- Sponsor
- Dr. D McIntosh & Dr. K Kjernisted Clinical Research Inc.
Breast Cancer
Safety and Efficacy of ALC in Breast Cancer in Subjects With Fatigue
The objective of this study is to evaluate the efficacy and safety of ALC in the treatment of non-anemic, breast cancer subjects who develop moderate or severe fatigue during adjuvant radiotherapy.
- Trial name
- NCT00555841
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Sigma-Tau Research, Inc.
Posttraumatic Stress Disorder (PTSD)
Neural Correlates of Early Intervention for Posttraumatic Stress Disorder (PTSD)
Background: Innovation: Over 150,000 soldiers are currently deployed in Iraq as part of Operation Iraqi Freedom (OIF), and 12% of returning OIF veterans have posttraumatic stress disorder (PTSD).
- Trial name
- NCT00665678
- Testing
- paroxetine
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Foundation for Atlanta Veterans Education and Research, Inc.
Participation in Nurse Visits
The Effect of Active Choice on Nurse Visit Participation
The goal of this project is to see if behavioral nudges will increase an individual's likelihood of participating in a nurse visit.
- Trial name
- NCT01250392
- Testing
- The Effect of Active Choice on Nurse Visit Participation
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- National Bureau of Economic Research, Inc.
Conversion From Brand Name to Generic Medication
The Impact of Social Proximity on Conversion to Generic Prescription Medications
The goal of this project is to understand the effects of receiving peer information on individuals' conversion rates from brand name prescription medication to generic prescription medication.
- Trial name
- NCT01251419
- Testing
- Social Proximity and Conversion to Generic Medications
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- National Bureau of Economic Research, Inc.
Chronic Low Back Pain
Prevalence of Potential Cytochrome P450 Pharmacokinetic Incident Drug-Drug Interactions Among Chronic Low Back Pain Patients Taking Opioid Analgesics and Associated Economic Outcomes
This study explored the prevalence of DDEs in a chronic pain population with cLBP and associated healthcare utilization and costs using a healthcare claims database.
- Trial name
- NCT01177280
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- NEMA Research, Inc.