Clinical trials: sponsored by Research Inc
Shoulder Injuries, Shoulder Disease
Cryopneumatic Device After Shoulder Surgeries
This study randomize patients to receive either a cryopneumatic device or standard care (ice and ice packs) following open or arthroscopic shoulder surgeries.
- Trial name
- NCT04185064
- Testing
- Game Ready ATX shoulder wrap; Game Ready GRPro 2.1, Standard Care
- Where
- 5 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Encore Research Inc.
Rheumatoid Arthritis, Myositis
Rheumatoid Arthritis and Myositis Cohort
The primary objective of this research is to establish a well characterized clinical and longitudinal cohort for individuals with Rheumatoid Arthritis (RA) and Myositis to create a place to maintain blood, urine, stool specimens…
- Trial name
- NCT05627089
- Sponsor
- Attune Health Research, Inc.
Rheumatoid Arthritis
The Effects of Acthar on Synovial Inflammation in Rheumatoid Arthritis
Patients will be assigned to receive either Depo Medrol or Acthar treatment. A synovial biopsy, blood draws, synovial fluid aspiration, and physician assessments will be performed before and after initiating treatment.
- Trial name
- NCT03511625
- Testing
- Acthar Injectable Product, Depo medrol
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Attune Health Research, Inc.
COVID-19 Vaccines
The COVID-19 Back-to-Normal Study: Analysis of Multiple Outcomes
During the study, members of different online and offline communities will be followed post COVID-19 vaccination. Injection-site (local) and systemic reaction data will be assessed on vaccination day and afterwards using either…
- Trial name
- NCT04832932
- Testing
- COVID-19 vaccines
- Where
- 5 sites in United States, Georgia and 2 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Mebo Research, Inc.
Atopic Dermatitis, Acne Rosacea
Inflammatory Cells From Various Pathologies
The objective of this experiment is to develop and validate in vitro methods to isolate inflammatory cells from skin biopsies for quantitative flow cytometry analysis.
- Conditions
- Atopic Dermatitis, Acne Rosacea, Acne Vulgaris
- Trial name
- NCT02270411
- Where
- Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Generalized Anxiety Disorder, Social Anxiety Disorder
Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide
Anxiety disorders affect over a quarter of the population, yet very little is known about the variables that predict treatment outcome.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03925987
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Hypertension
The Safety and Efficacy of an NAD+ Boosting Product Together With a Low Carbohydrate Diet in Adults With Mild Hypertension and Eligible for Normal-standard-of-care
The objective of this study is to evaluate the safety and efficacy of Limitless, in combination with a low-carbohydrate diet, after 30 days of supplementation in an adult population.
- Trial name
- NCT05298410
- Testing
- Limitless
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Limitless Research Inc.
Adolescents With Early Life Stress
Augmented Mindfulness Training for Resilience in Early Life
This project aims to determine whether neurofeedback augmented mindfulness intervention increases the plasticity in brain areas affected by exposure to early life adversity in youth.
- Trial name
- A-MindREaL (NCT04053582)
- Testing
- AMT
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anorexia Nervosa, Major Depressive Disorder
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or…
- Conditions
- Anorexia Nervosa, Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT02615119
- Testing
- Isoproterenol, Normal saline
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Depression, Anxiety and Fear
Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression
Over 50% of patients with major depressive disorder (MDD) do not respond to initial treatment and relapse is common. In particular, comorbid depression and anxiety disorders are associated with more treatment resistance.
- Trial name
- NCT04948944
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Components of REAL Essentials
Components Study of REAL Essentials
The Components Study of REAL Essentials (REA) is a descriptive implementation and outcome study. This study aims to identify the components that matter most for promoting positive health behaviors and outcomes among adolescents.
- Trial name
- REA (NCT06112912)
- Testing
- REAL Essentials Advance
- Where
- United States
- Volunteers
- 1,301 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Epilepsy, Benign Neonatal
Efficacy and Safety of Intravenous Phenobarbital in Neonatal Seizures
This is a randomized, double-blind, parallel-group, Phase 3 study to evaluate the efficacy of the administration of phenobarbital sodium injection in neonates who have suffered from electrographic or electroclinical seizure.
- Trial name
- NCT04320940
- Testing
- Phenobarbital Sodium Injection
- Where
- 8 sites in United States, Jordan
- Volunteers
- 4 people
- Sponsor
- NEMA Research, Inc.
Amphetamine-Type Substance Use Disorder
Floatation-REST in Methamphetamine Use Disorder: A Pilot Study
This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 50 individuals receiving treatment for…
- Trial name
- NCT05799209
- Testing
- Float Pool, Float Chair
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Atrial Fibrillation, Implantable Cardioverter Defibrillator
Breathing Intervention for Cardiac Anxiety
This study examines the impact of a breathing training intervention on cardiorespiratory sensations and anxiety in adults with cardiac arrhythmias.
- Trial name
- NCT02916550
- Testing
- Breathing exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Generalized Anxiety Disorder, Agoraphobia
Examining the Effects of Reduced Environmental Stimulation on Anxiety
The studies proposed in this protocol aim to explore the anxiolytic properties of floating as it relates to the central and autonomic nervous system.
- Conditions
- Generalized Anxiety Disorder, Agoraphobia, Panic Disorder, PostTraumatic Stress Disorder
- Trial name
- NCT03051074
- Testing
- Floating, Comparison
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Eating Disorder
A New Measure of Body Image in Eating Disorders
This study aims to compare a new electronic instrument called (here referred to as the 'Body App') with traditional paper and pencil rating scales for assessing how individuals with eating disorders evaluate their body image.
- Trial name
- NCT03758326
- Testing
- Body App
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anorexia Nervosa
Augmented Interoceptive Exposure Training in Anorexia Nervosa
The researchers propose to utilize a pharmacological approach involving infusions of the sympathomimetic agent isoproterenol to repeatedly trigger cardiorespiratory sensations and anxiety during meal anticipation, to facilitate…
- Trial name
- NCT03019081
- Testing
- Isoproterenol
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anorexia Nervosa
Floatation-REST and Anorexia Nervosa
The study proposed in this protocol aims to document the effect of Floatation-REST (reduced environmental stimulation therapy) on symptoms of anorexia nervosa.
- Trial name
- NCT03610451
- Testing
- Floatation-REST plus usual care, Usual care
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Generalized Anxiety Disorder, Social Anxiety Disorder
Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression
This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 75 participants with clinical anxiety and…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03899090
- Testing
- Float pool, Float chair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Trichomonas Infection
A Phase 3 Study of Solosec® for the Treatment of Trichomoniasis
This is a Phase 3, multi-center, prospective, randomized, placebo-controlled, delayed treatment, double-blind, study to evaluate the effectiveness, and safety of a single, oral dose of Solosec® containing 2 grams of secnidazole…
- Trial name
- NCT03935217
- Testing
- Secnidazole
- Where
- 11 sites in United States
- Volunteers
- 147 people
- Sponsor
- Lupin Research Inc