Clinical trials: sponsored by Samsung Medical Center
Equipment and Supplies, Augmented Reality
Effects of Augmented Reality-based Rapid Blood Transfusion (Level-1®)
The goal of this clinical trial is to compare the effectiveness of AR-based training with traditional guideline-based self-learning in practical nurses without prior Level-1® experience.
- Conditions
- Equipment and Supplies, Augmented Reality, Nurse's Role
- Trial name
- NCT06506851
- Testing
- AR-based Training with Microsoft HoloLens 2®, Traditional Guideline-based Self-Learning
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Samsung Medical Center
Gastric Cancer, Gastrectomy
The Effect of Intensive Dietary Education on Nutritional Status After Gastrectomy(SING)
Radical gastrectomy has been known as the most effective treatment of curable gastric cancer.However, there is a high risk of malnutrition and weight loss after a gastrectomy which may be attributed to inadequate oral…
- Trial name
- SING (NCT04798820)
- Testing
- Dietary education(nutritional counselling)
- Where
- South Korea
- Volunteers
- 358 people
- Sponsor
- Samsung Medical Center
High Risk Prostate Carcinoma
Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy and Hormone Therapy With SpaceOAR TM for Patients With High - Risk Localized Prostate Cancer (DESAR-H)
Dose increase after injection of biodegradable material A safety study of high-risk prostate cancer patients who underwent low-fractionation curative radiation therapy and hormone therapy
- Trial name
- DESAR-H (NCT06461793)
- Testing
- Dose increase after injection of biodegradable material A safety study of high-risk prostate cancer patients
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Samsung Medical Center
Low-to-intermediate-risk Prostate Carcinoma
Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy With SPACEOAR TM for Patients With Low-to-intermediate Risk Localized Prostate Cancer (DESAR-L)
A single institution with a single group, a phase II study, low- and medium-risk studies performed after biodegradable substance injection prostate cancer dosage increase.
- Trial name
- DESAR-L (NCT06461819)
- Testing
- Low- and medium-risk studies performed after biodegradable substance injection prostate cancer dose increase.
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Samsung Medical Center
Kidney Neoplasm
Systemic Treatment Alone Versus Systemic Treatment Plus Radiotherapy in Oligometastatic Renal Cell Carcinoma
To evaluate whether incorporating locoregional radiotherapy in the treatment of oligometastatic renal cell carcinoma, including inductive oligometastases, along with standard systemic therapy, contributes to improved…
- Trial name
- SABLOR (NCT06467097)
- Testing
- SBRT(Stereotatic Body Radiation Therapy)
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Samsung Medical Center
Endometrial Cancer
Postoperative Hypofractionated Intensity-modulated Radiotherapy Endometrial Cancer
To investigate the non-inferiority of disease-free survival in women who received hypofractionated intensity-modulated whole pelvic radiation therapy (2.5 Gy x 16 fractions) after curative surgery for stage III endometrial cancer.
- Trial name
- NCT05876130
- Testing
- POHIM_EM
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Samsung Medical Center
Lung Neoplasms
The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer
The purpose of this study is to examine the impact of physical activity on the postoperative symptoms, complication, and quality of life.
- Trial name
- NCT03705546
- Where
- South Korea
- Volunteers
- 1,050 people
- Sponsor
- Samsung Medical Center
Esophageal Cancer
Chemoradiotherapy Versus Esophagectomy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma
This is a randomized noninferiority multicenter trial. Patients will be stratified according to the participating hospital. Patients will be randomized to one of the treatment arms.
- Trial name
- ASSURE (NCT03306901)
- Testing
- Esophagectomy, 5-fluorouracil, Cisplatin
- Where
- 9 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Samsung Medical Center
Liver Transplantation, Inpatients
Pilot Study for the Validity of a Content-based Information Provision Tool Aimed at Improving the Hospitalization Experience of Liver Transplant Patients
The investigators aim to evaluate the improvement of the inpatient experience and the usability of a content-based tool (a brochure).
- Trial name
- NCT06424808
- Testing
- Consolidating content on a single website and providing access to it via QR codes in a brochure format
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Cardiovascular Diseases, Atherosclerosis
Maternal and Offspring Outcomes in Pregnant Women With Pre-existing ASCVD
A growing body of evidence supports associations between cardiovascular health and adverse pregnancy outcome and between adverse pregnancy outcome and atherosclerotic cardiovascular disease and builds on the well-established…
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Pregnancy Complications, Adverse Cardiac Event
- Trial name
- CVD_OBS (NCT06406998)
- Testing
- Pre-existing atherosclerotic cardiovascular disease
- Where
- South Korea
- Volunteers
- 5,461,222 people
- Sponsor
- Samsung Medical Center
Parkinson Disease
Effect of Simultaneous Dual Stimulation on Freezing of Gait in Parkinson's Disease
The purpose of this study is to investigate the effect of dual-mode non-invasive brain stimulation (NIBS) with high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex of the lower leg and…
- Trial name
- NCT02850159
- Testing
- rTMS and tDCS, rTMS
- Volunteers
- 32 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Stents
P2Y12 Inhibitor Monotherapy Versus Extended DAPT in Patients Treated With Bioresorbable Scaffold
This study aimed to compare the efficacy and safety of P2Y12 inhibitor monotherapy versus extended dual antiplatelet therapy (DAPT) following 12-month of DAPT in patients undergoing percutaneous coronary intervention (PCI) with…
- Conditions
- Coronary Artery Disease, Stents, Atherosclerosis
- Trial name
- SMART-CHOICEII (NCT03119012)
- Testing
- Clopidogrel, Ticagrelor, Aspirin
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Coronary Restenosis
DEB Versus 2nd Generation DES in Patients With In-Scaffold Restenosis of Bioresorbable Vascular Scaffold
The aim of the study is to compare angiographic outcomes following revascularization using drug-eluting balloon (DEB) versus 2nd generation drug-eluting stent (DES) in treatment of Bioresorbable Vascular Scaffold Restenosis.
- Trial name
- SMART-BRS-ISR (NCT03074305)
- Testing
- PCI for in-bioresorbable scaffold stenosis
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Acute Hypoxemic Respiratory Failure
Comparison Physiological Effects According to Preoxygenation Method Using EIT
Hypoxemia during endotracheal intubation is one of this procedure's most frequent and severe complications, which can lead to cardiac arrest and other adverse outcomes.
- Trial name
- PreoxyEIT (NCT05962073)
- Testing
- HFNC
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Acute Myocardial Infarction
FFR Versus Angiography-Guided Strategy for Management of AMI With Multivessel Disease
The aim of the study is to compare clinical outcomes following fractional flow reserve (FFR)-guided versus angiography only guided strategy in treatment of non-infarction related artery (non-IRA) stenosis in patients with acute…
- Trial name
- FRAME-AMI (NCT02715518)
- Testing
- PCI using 2nd generation drug-eluting stent
- Where
- South Korea
- Volunteers
- 1,292 people
- Sponsor
- Samsung Medical Center
Ischemic Heart Disease
Multicenter Registry for Angiography-Derived Quantitative Flow Ratio
1. to investigate the feasibility and diagnostic performance of contrast quantitative flow ratio (QFR) for identifying the functional significance of intermediate degree stenotic lesions in all-comer patients with coronary artery…
- Trial name
- QFRRegistry (NCT03791788)
- Testing
- QFR assessment
- Where
- 5 sites in South Korea
- Volunteers
- 524 people
- Sponsor
- Samsung Medical Center
Delirium, Postoperative
Modulating Surgery-Induced Blood-Brain Barrier Disruption in Elderly
Postoperative delirium (POD) is the most common complications (~50-60%) in elderly and major challenges to our rapidly growing aging population.
- Trial name
- NCT06090955
- Testing
- Dexmedetomidine Injection [Precedex], Lidocaine IV, normal saline
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Samsung Medical Center
Carcinoma, Non-Small-Cell Lung, Immune Checkpoint Inhibitors
Imaging Biomarkers for Immune Checkpoint Inhibitor Treatment in Patients With Non-small Cell Lung Cancer
1. Hypothesis : imaging biomarkers of tumor measured by F-18 fluorodeoxyglucose (FDG) positron emission tomography(PET)/computed tomography(CT) is correlated with immune checkpoint inhibitor (ICI) treatment response and patient…
- Trial name
- IBFIC (NCT05260606)
- Testing
- F-18 FDG PET/CT
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Cancer
Time From PCI to Cancer Surgery and Cardiovascular and Oncologic Outcomes
To evaluate the association between time from PCI to cancer surgery and cardiovascular and oncologic outcomes in early-stage cancer patients, A retrospective, population-based cohort study was conducted using data from the Korean…
- Trial name
- NCT06357000
- Volunteers
- 3,621 people
- Sponsor
- Samsung Medical Center
Thymic Epithelial Tumor
Rivoceranib in Patients With Metastatic Thymic Epithelial Tumor
PURPOSE: To evaluate the efficacy and safety of Rivoceranib in patients with metastatic thymic epithelial tumors who developed resistance on first-line therapy.
- Trial name
- NCT06200233
- Testing
- Rivoceranib
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center