Clinical trials: sponsored by Samsung Medical Center
Lung Cancer
Radiomic Assessment in NSCLC: Correlation Between Multiparametric Imaging Biomarkers and Genetic Biomarkers
The purpose of this study is to evaluate relationships between multiparametric imaging biomarkers and genetic analysis in NSCLC patients.
- Trial name
- NCT01585545
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Pediatrics
Evaluation of Social Robot Usability for Pediatric Patients and Carers
This study is conducted for a mixed methods study. Subjects are 20 child patients and 20 their carers. First, Participants use and interact with a social robot. The robot is controlled by researcher with the wizard of oz. method.
- Trial name
- NCT04993599
- Testing
- Social robot interaction
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Preterm Premature Rupture of Membrane
Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane
The purpose of this study is to compare the neonatal outcome and infant neurologic outcome whose mother were treated with cefazolin plus clarithromycin for one week or until delivery after preterm premature rupture of membrane.
- Trial name
- NCT01503606
- Testing
- Cefazolin, Clarithromycin
- Where
- South Korea
- Volunteers
- 151 people
- Sponsor
- Samsung Medical Center
Prostatic Neoplasm
An Open Label Phase II Study of Biweekly Docetaxel Plus Androgen-Deprivation Therapy in Patients With Previously-Untreated, Metastatic, Prostatic Adenocarcinoma
Study of Biweekly Docetaxel plus Androgen-Deprivation Therapy (ADT) in Patients with Previously-Untreated, Metastatic, Prostatic Adenocarcinoma
- Trial name
- NCT03061643
- Testing
- Docetaxel, Androgen-Deprivation Therapy (ADT)
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Samsung Medical Center
Urinary Bladder
A Prospective Study of Neoadjuvant Chemotherapy With Gemcitabine/Platinum in Muscle-Invasive or Locally-Advanced Urothelial Carcinoma of Bladder
Previously-untreated, high-risk (>T3 and/or N+) muscle-invasive bladder cancer (MIBC) cisplatin 60 mg/m2 on day 1 and gemcitabine 1000 mg/m2 on days 1, 8 and 15. On day 1
- Trial name
- NCT03061630
- Testing
- Gemcitabine, Cisplatin
- Where
- 2 sites in South Korea
- Volunteers
- 49 people
- Sponsor
- Samsung Medical Center
Urothelial Carcinoma
Study of Tipifarnib in Patients With Previously-Treated, Advanced, HRAS Mutant Urothelial Carcinoma
Platinum-based chemotherapy is now regarded a standard first-line treatment for patients with advanced urothelial carcinoma (UC).
- Trial name
- NCT02535650
- Testing
- tipifarnib
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Samsung Medical Center
Lung Cancer, Diagnoses Disease
Liquid Biopsy Using Methylation Sequencing for Lung Cancer
This study aims to investigate the utility of circulating tumor DNA (ctDNA) methylation sequencing in the diagnosis of primary lung cancer.
- Trial name
- NCT04253509
- Testing
- Circulating Tumor DNA Methylation Sequencing
- Where
- South Korea
- Volunteers
- 280 people
- Sponsor
- Samsung Medical Center
Stroke
Effects of Comprehensive Augmented and Virtual Reality in Stroke Patients
The purpose of this study was to assess the efficacy of augmented and virtual reality-based rehabilitation programs on improving upper extremity function in subacute stroke patients.
- Trial name
- NCT05193539
- Testing
- Augmented reality and virtual reality rehabilitation, Conventional occupational therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Relapsed or Refractory Anaplastic Large Cell Lymphoma & Hodgkin Lymphoma
Registry of BrentuximabVedotinin Patients With R/R Anaplastic Large Cell Lymphoma or Classical HL
In case of relapsed or refractory ALK-negative ALCL patients, high-dosage chemotherapy/ stem cell transplantation is a universal salvage option for patients with sensitivity to anti-cancer treatment and a relatively successful…
- Trial name
- BRAVO (NCT03766516)
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Aortic Valve Insufficiency
Open Label RCT for Chronic Severe AR : Entresto vs. CCB/ARB
The purpose of this study is to assess the efficacy of sacubitril-valsartan compared to the combination of ARB/CCB on left ventricular remodeling in patients with chronic aortic valve regurgitation.
- Trial name
- REVERSE-AR (NCT05212597)
- Testing
- Sacubitril-valsartan, Amlodipine-losartan
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Lower Back Pain, Knee Osteoarthritis
Clinical Efficacy of IoMT-based Exercise Program for the Elderly
The purpose of this study is to evaluate the efficacy of Internet of Medical Things (IoMT) based home exercise programs for the elderly with degenerative knee arthritis or chronic low back pain.
- Trial name
- NCT05197010
- Testing
- Home based exercise program via a smartphone application
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Gynecologic Cancer, Lymphedema of Leg
Home-based Intermittent Pneumatic Compression Therapy for Gynecologic Cancer
Investigators conducted a prospective study of cancer patients to investigate the efficacy, quality of life, satisfaction, and safety of a home-based intermittent pneumatic compression (IPC) device during the maintenance phase of…
- Trial name
- NCT05193357
- Testing
- home-based intermittent pneumatic compression (IPC) device
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Frozen Shoulder
Real-time Interactive Digital Healthcare System in Frozen Shoulder; Randomized Controlled Trial
This study aims to examine the effect of hospital-home linkage short-term rehabilitation therapy using real-time interactive digital healthcare system (Uincare Homeplus) in frozen shoulder.
- Trial name
- NCT04316130
- Testing
- Uincare Homeplus, Brochure
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Salivary Duct Carcinoma
Combination of Nanoxel and Herzuma in Salivary Duct Carcinoma
1. Study outline This is a multicenter, single-arm, phase II trial to evaluate the efficacy and safety of nanoxel plus herzuma combination chemotherapy in patients with metastatic salivary ductal cancer.
- Trial name
- NCT03614364
- Testing
- nanoxel, herzuma
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Samsung Medical Center
Breast Cancer
Real-time Interactive Digital Healthcare System in Patients With Breast Cancer; Randomized Controlled Trial
This study aims to examine the effect of hospital-home linkage short-term rehabilitation therapy using real-time interactive digital healthcare system (Uincare Homeplus) in post-operative patients with breast cancer.
- Trial name
- NCT04316156
- Testing
- Uincare Homeplus, Brochure
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Ventilator Lung
Assessment of Process and Outcome of Protocol-based Weaning From Mechanical Ventilation in the Medical Patients
This is a prospective, single-center, observational study to describe characteristics of weaning process and factors associated with duration of weaning and its outcomes in all consecutive adult (aged 19 years and older) patients…
- Trial name
- NCT05134467
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Radical Cystectomy, Muscle-Invasive Bladder Carcinoma
Clinical Utility of VI-RADS in Diagnosis of MIBC
Bladder Cancer (BCa) is the 9th most common cancer worldwide. In general, BCa is presented as a non-muscle invasive bladder cancer (NMIBC) in 70% of patients and treated with transurethral resection of bladder tumor (TUR-BT).
- Conditions
- Radical Cystectomy, Muscle-Invasive Bladder Carcinoma, Multiparametric MRI, Vesical Imaging Report and Data System
- Trial name
- NCT05097404
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Samsung Medical Center
Breast Cancer
Omitting vs. Doing Intraoperative Frozen Section Biopsy for Margin Status in Breast Conserving Surgery
Study phase: 3 Indication: Breast cancer patients undergoing breast conserving surgery Primary objectives: To determine the effect of selective omission of intraoperative margin evaluation via frozen section on margin positive…
- Trial name
- OFF-MAP (NCT03975179)
- Testing
- Omission of intraoperative frozen section biopsy for margin status, Frozen section biopsy for margin status
- Where
- 2 sites in South Korea
- Volunteers
- 1,292 people
- Sponsor
- Samsung Medical Center
COPD Exacerbation
Physical Activity in Chronic Obstructive Pulmonary Disease(COPD) Acute Exacerbation Patients
Patients who are suffering from Chronic Obstructive Pulmonary Disease (COPD) had a decreased level of physical activity which is consequentially related to another acute exacerbation event.
- Trial name
- NCT03437252
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center
Implantable Cardioverter Defibrillator, Atrial Fibrillation
Atrial Sensing Capability for Better Detection of Atrial Fibrillation
This prospective multi-center randomized controlled study aims to compare atrial fibrillation detection and inappropriate therapy according to activation of atrial sensing capability in patients with implantable cardioverter…
- Conditions
- Implantable Cardioverter Defibrillator, Atrial Fibrillation, Cardiac Event, Cardiac Arrhythmia
- Trial name
- NCT03932604
- Testing
- Atrial sensing On mode
- Where
- 28 sites in South Korea
- Volunteers
- 640 people
- Sponsor
- Samsung Medical Center