Clinical trials: sponsored by Samsung Medical Center
Macular Holes, Retinal Detachment
Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery
The purpose of this study is to evaluate the effects of a structured exercise program on musculoskeletal pain of patients in face-down posture after retinal surgery.
- Trial name
- NCT04535622
- Testing
- A structured exercise
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Samsung Medical Center
Lung Adenocarcinoma, Stage I
Postoperative Pembrolizumab for the Patients Who Have Solid Predominant or Micropapillary Lung Adenocarcinoma With Pathologic Stage I and Primary Tumor Than 4 cm
A single center, open-label, single arm study in patients who have solid or micropapillary adenocarcinoma with pathologic stage I and primary tumor no more than 4 cm. Pembrolizumab 200 mg every 3 weeks
- Trial name
- NCT03254004
- Testing
- Pembrolizumab
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Samsung Medical Center
Bladder Pain Syndrome, Pentosan Polysulfate
Efficacy Study of Pentosan Polysulfate Sodium,Hydrodistension and Combination Therapy for Bladder Pain Syndrome
The efficacy of pentosan polysulfate sodium, hydrodistension and combination therapy in patients with bladder pain syndrome.
- Conditions
- Bladder Pain Syndrome, Pentosan Polysulfate, Hydrodistension
- Trial name
- NCT01895153
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- Samsung Medical Center
Non Small Cell Lung Cancer
Vandetanib in Advanced NSCLC With RET Rearrangement
The purpose of this study is to investigate the efficacy and safety of vandetanib, in patients with advanced non-small-cell lung cancer harboring RET gene rearrangement.
- Trial name
- NCT01823068
- Testing
- Vandetanib
- Where
- 2 sites in South Korea
- Volunteers
- 17 people
- Sponsor
- Samsung Medical Center
Nontuberculous Mycobacterial Lung Disease
Study of Nontuberculous Mycobacterial Lung Disease
The incidence of pulmonary disease caused by nontuberculous mycobacteria (NTM) has been increasing, and a substantial proportion of these patients have no preexisting lung disease and no demonstrable immunodeficiency.
- Trial name
- NCT00970801
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Samsung Medical Center
Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Ramucirumab/Paclitaxel as Second-line Treatment in Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma With Integrative Genomic Analysis
Vascular endothelial growth factor is expressed in gastric cancer, and expression has been associated with more aggressive clinical disease.
- Trial name
- NCT02628951
- Testing
- Ramucirumab, Paclitaxel
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Samsung Medical Center
Postoperative Atelectasis, Ventilator Lung
Ventilator-driven Alveolar Recruitment Maneuver
During laparoscopic surgery, gas infiltration and head down position cause pulmonary atelectasis. Alveolar recruitment maneuvers are beneficial in reopening collapsed alveoli and improving lung mechanics.
- Conditions
- Postoperative Atelectasis, Ventilator Lung, Atelectasis, Recruitment
- Trial name
- NCT04258202
- Testing
- Alveolar recruitment maneuver
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Samsung Medical Center
Early Stage Breast Cancer
ABUS for Early-stage Breast Cancer
While the role of automated breast ultrasound (ABUS) as an alternative to hand-held ultrasound (HHUS) in breast cancer screening has been established, the use of ABUS in preoperative evaluation of newly diagnosed breast cancer…
- Trial name
- NCT04607473
- Testing
- automated breast ultrasound (ABUS)
- Where
- 3 sites in South Korea
- Volunteers
- 675 people
- Sponsor
- Samsung Medical Center
Relapsed and/or Refractory Cutaneous T-cell Lymphoma
Bortezomib/Dexamethasone Therapy in Patients With Relapsed and/or Refractory Cutaneous T-cell Lymphoma
the efficacy and safety of bortezomib / dexamethasone combination therapy in patients with relapsed or refractory T-cell lymphoma who have failed one or more treatments. primary purpose 1.
- Trial name
- NCT03487133
- Testing
- bortezomib/dexamethasone
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Samsung Medical Center
Diffuse Large B Cell Lymphoma
Bortezomib Maintenance in High Risk DLBCL
This study is an Open-labeled, multicenter Phase II study of Bortezomib for maintenance therapy in patients with high risk diffuse large B cell lymphoma (DLBCL).
- Trial name
- Borma (NCT01965977)
- Testing
- Bortezomib
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Samsung Medical Center
Chest Pain, Electrocardiography
Timely Acquirement of 12-lead ECG Using Patchy-type Wireless Device Among Patient With Chest Pain
In this study, the investigators compare timely acquirement of 12-lead ECG using patchy-type wireless versus using standard 12-lead ECG system among patient with chest pain in ED.
- Trial name
- NCT04048733
- Testing
- patchy-type wireless 12-lead ECG
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Peripheral T-cell Lymphoma
Compare Efficacy of CHOP Versus Fractionated ICED in Transplant-eligible Patients With Previously Untreated PTCL
This study is a Randomized Phase II Study to Compare Efficacy of CHOP versus Fractionated ICED in Transplant-eligible Patients with Previously Untreated Peripheral T-cell Lymphoma.
- Trial name
- NCT02445404
- Testing
- CHOP, fractionated ICED
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Samsung Medical Center
Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma
Study of Ibrutinib in Combination With Rituximab-CHOP in Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma
This study was conducted to evaluate the complete response rate of Ibrutinib + R-CHOP in patients with Epstein-Barr virus-positive diffuse large B-cell lymphoma.
- Trial name
- NCT02670616
- Testing
- Ibrutinib, Rituximab, Cyclophosphamide
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Atrial Fibrillation, Rivaroxaban
Rivaroxaban in Elderly NVAF Patients With or Without Renal Impairment
Study Type and Design Prospective, Observational Study Rivaroxaban in Elderly AF patients with or without renal impairment in Korea This study will investigate effectiveness and safety in elderly patients, the result from…
- Conditions
- Atrial Fibrillation, Rivaroxaban, Elderly, Renal Insufficiency
- Trial name
- XAIENT (NCT04096547)
- Testing
- Rivaroxaban
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Samsung Medical Center
Relapsed and/or Refractory Non-Hodgkin T-cell Lymphoma
Phase II of Lenalidomide After Salvage Therapy in R/R Non-Hodgkin T-cell Lymphoma
This study is to evaluate the efficacy and safety of lenalidomide maintenance therapy in patients with T-cell lymphoma who have undergone more than one treatment or relapsed after treatment and who acquired a response of more…
- Trial name
- Lemon-T (NCT03730740)
- Testing
- Lenalidomide 25mg
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Samsung Medical Center
Extranodal NK-T-Cell Lymphoma
VP-16, Ifosfamide, Dexamethasone, L-asparaginase Chemotherapy in Patients With Extranodal Natural Killer T Cell Lymphoma (VIDL+ASCT)
Open-labeled, multicenter phase II study of VIDL (VP-16, Ifosfamide, Dexamethasone, L-asparaginase) chemotherapy followed by high-dose chemotherapy and autologous stem cell transplantation in patients with stage III/IV extranodal…
- Trial name
- VIDL+ASCT (NCT02544425)
- Testing
- Etoposide, Ifosfamide, Dexamethasone
- Where
- 2 sites in South Korea
- Volunteers
- 27 people
- Sponsor
- Samsung Medical Center
Chest Pain, Electrocardiography
Timely Acquirement of 12-lead ECG Using Patchy-type Wireless Device by Emergency Medical Technician in Ambulance
In this study, the investigators compare timely acquirement and effectiveness of 12-lead ECG using patchy-type wireless versus using defibrillator which contain ECG examination function in ambulance.
- Trial name
- NCT04114760
- Testing
- patchy-type wireless ECG, defibrillator ECG
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Mantle Cell Lymphoma
Ibrutinib for Relapsed or Refractory Mantle Cell Lymphoma
To review the efficacy and the safety of ibrutinib in patients with relapsed or refractory mantle cell lymphoma (MCL).
- Trial name
- MCLRR (NCT04061850)
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Samsung Medical Center
Multiple System Atrophy, Cerebellar Variant (Disorder), Spinocerebellar Ataxias
Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia
The present study investigated the efficacy and safety of combination treatment of repetitive transcranial magnetic stimulation (rTMS) and physical therapy (PT) in patients with cerebellar variant of multiple system atrophy…
- Trial name
- NCT04595578
- Testing
- Cerebellar repetitive transcranial magnetic stimulation
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Samsung Medical Center
Non-Hodgkin T-cell Lymphoma
Intercontinental Cooperative Non-Hodgkin T-cell Lymphoma Prospective Registry Study
The better understanding of non-Hodgkin T-cell lymphoma is essential for establishing effective treatment strategy for non-Hodgkin T-cell lymphoma.
- Trial name
- NCT02691351
- Testing
- Prospective Registry
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center