Clinical trials: sponsored by Samsung Medical Center
Healthy
Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects.
- Trial name
- NCT03486795
- Testing
- M1 stimulation, PMC stimulation
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Brain Injuries, Minimally Conscious State
Effects of Whole-body Vibration Exercise in Brain Injury Patients With Minimally Conscious State
The purpose of this study is to investigate the effect of the whole body vibration exercise on cortical activity and consciousness Level in brain injury patients with minimally conscious state.
- Trial name
- NCT03389113
- Testing
- Whole body vibration, Exersice
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Samsung Medical Center
Stroke, Gait Disorders, Neurologic
Most Effective Stimulation Site in Transcranial Direct Current Stimulation for Gait Recovery After Stoke
The aim of this study is to investigate the most effective stimulation site in transcranial direct current stimulation for gait recovery after stroke.
- Trial name
- NCT03460886
- Testing
- Ipsilesional stimulation, Contralesional stimulation, Walking on treadmill
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Mild Cognitive Impairment
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Mild Cognitive Impairment
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of mild cognitive impairment (MCI) patients' cognitive function by altering the cortical…
- Trial name
- NCT03647345
- Testing
- High-frequency rTMS on left DLPFC+anodal tDCS on right DLPFC, High-frequency rTMS on left DLPFC+cathodal tDCS on right DLPFC
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Samsung Medical Center
Stroke
White Matter Integrity According to BDNF Genotype After Stroke
The aim of this study was to investigate differential plastic changes of fractional anisotropy (FA) in the corticospinal tract (CST), the intrahemispheric corticocortical tract from the primary motor cortex to ventral premotor…
- Trial name
- NCT03647787
- Testing
- observational study
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Samsung Medical Center
Stroke
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Stroke
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03390192
- Testing
- Dual-mode stimulation
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Samsung Medical Center
Multiple System Atrophy, Cerebellar Variant (Disorder)
tDCS for Multiple System Atrophy With Cerebellar Feature
The aim of study is to investigate most effective site for control the motor coordination using transcranial direct current stimulation in multiple system atrophy with cerebellar feature
- Trial name
- NCT04092556
- Testing
- transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Samsung Medical Center
Pain, Postoperative
Gradual Withdrawal of Remifentanil Infusion Reduced Postoperative Pain and Opioid Requirement During Breast Surgery
Although remifentanil provides profound analgesia during operation, postoperative occurrence of hyperalgesia and tolerance after remifentanil administration could be a challenge to the postoperative pain control.
- Trial name
- NCT03756233
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Lung Cancer (Diagnosis), Circulating Tumor Cell
Liquid Biopsy in Lung Cancer
The purpose of this study is to assess clinical utility of combined circulating tumor cell (CTC) and circulating tumor DNA (ctDNA) in the diagnosis of primary lung cancer.
- Trial name
- NCT03479099
- Where
- South Korea
- Volunteers
- 111 people
- Sponsor
- Samsung Medical Center
Follicular Lymphoma
Clinical Outcomes of Early-progressed Follicular Lymphoma in Korea
This retrospective study was proposed by the investigators to analyze treatment status and outcome in patients with early relapsed follicular lymphoma.
- Trial name
- FLPOD24 (NCT04048395)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Samsung Medical Center
Healthy Donors for Liver Transplantation
Comparison of Postoperative Outcome of Hepatectomy for Living Donors According to Three Different Incision
Living donor liver transplantation (LDLT) is an important option for patients with end-stage liver disease requiring liver transplantation. When performing LDLT, the safety and well being of donors is of the utmost importance.
- Trial name
- NCT02413983
- Testing
- hepatectomy conventional incision, hepatectomy midline incision, hepatectomy transverse incision
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Pain, Postoperative, Nociceptive Pain
Intraoperative Nociception and Postoperative Pain
If the individual patient's pain is assessed and the amount of analgesic needed after surgery is predicted, appropriate injection of pain control and excessive injection of narcotic analgesic can be prevented.
- Conditions
- Pain, Postoperative, Nociceptive Pain, Analgesics
- Trial name
- NCT03761433
- Testing
- SPI group
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Cryptogenic Embolic Stroke, Active Cancer
Identification the Cause of Cerebral Infarction in Patients With Cancer
Although there has been increasing interest in the association between cancer and cerebrovascular disease, the underlying pathophysiology of stroke in cancer patients is still not fully understood.
- Trial name
- NCT02212496
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Samsung Medical Center
Esophageal Squamous Cell Carcinoma
Genome-wide Association Study
To explore biomarkers predictive of clinical response to Taxane/5-FU/platinum based chemotherapy in esophageal squamous cell carcinoma. To identify negative predictive markers to 5-FU/platinum/Taxane.
- Trial name
- NCT01498757
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Colon Cancer
Study Investigating the Role of Oxaliplatin Duration in Modified FOLFOX-6 or CAPOX Regimen as Adjuvant Colon Cancer Therapy
This study is designed to confirm that first 3 months of oxaliplatin in 6 months of modified FOLFOX-6 or CAPOX treatment is not inferior to 6 months of oxaliplatin in modified FOLFOX-6 or CAPOX treatment in terms of disease free…
- Trial name
- NCT01092481
- Testing
- oxaliplatin
- Where
- 17 sites in South Korea
- Volunteers
- 1,580 people
- Sponsor
- Samsung Medical Center
Biliary Tract (Intrahepatic, Extrahepatic Cholangiocarcinoma, Gall Bladder) Cancer
Study of GEMOX(Gemcitabine/Oxaliplatin) Versus XELOX(Xeloda/Oxaliplatin) in Advanced Biliary Tract Carcinoma
The objective of the trial is to compare Progression free survival between GEMOX (gemcitabine/oxaliplatin)vs XELOX(capecitabine/oxaliplatin)in metastatic or unresectable Biliary tract carcinoma patients.
- Trial name
- NCT01470443
- Testing
- Oxaliplatin
- Where
- South Korea
- Volunteers
- 240 people
- Sponsor
- Samsung Medical Center
Biliary Tract Cancer
XELOX in Advanced Biliary Tract Carcinoma After Failure of Gemcitabine-based Chemotherapy
Phase II study of second line capecitabine plus oxaliplatin (XELOX) in patients with advanced biliary tract carcinoma after failure of gemcitabine-based chemotherapy.
- Trial name
- NCT02350686
- Testing
- capecitabine, oxaliplatin
- Where
- South Korea
- Volunteers
- 67 people
- Sponsor
- Samsung Medical Center
Stomach Neoplasms
Trial of Single Agent AZD2014 in RICTOR Amplified GC Patients as Second-line Therapy
Phase II trial of AZD2014 in RICTOR amplified or overexpressed GC patients as second-line chemotherapy AZD2014 50mg BD continuous schedule of a 28 day cycle
- Trial name
- AZD2014 (NCT03061708)
- Testing
- AZD2014
- Where
- South Korea
- Volunteers
- 1 people
- Sponsor
- Samsung Medical Center
Advanced Gastric Adenocarcinoma
Trial of AZD5363 Plus Paclitaxel /AZD2014 Plus Paclitaxel in Biomarker Negative (PIK3CA/MEK/RAS/TP53/MET) Gastric Adenocarcinoma Patients as Second-line Chemotherapy
Phase II trial of AZD5363 plus paclitaxel / AZD2014 plus paclitaxel in biomarker negative (PIK3CA/MEK/RAS/TP53/MET) advanced gastric adenocarcinoma patients as second-line chemotherapy. Each arm is composed of 25 patients.
- Trial name
- NCT02449655
- Testing
- AZD5363, paclitaxel, AZD2014
- Where
- South Korea
- Volunteers
- 27 people
- Sponsor
- Samsung Medical Center
Solid Tumor
Phase II Trial of Vistusertib（AZD2014） Single Agent in TSC1or 2 Null or TSC 1/2 Mutation Solid Cancer Patients Refractory to Standard Chemotherapy
Patients with TSC1/2 mutated refractory solid cancer will receive vistusertib(AZD2014) monotherapy. Study-arm is composed of 27 patients. Vistusertib(AZD2014) 50mg BD continuous schedule of a 28 day cycle as a monotherapy
- Trial name
- TSC1/2_SC (NCT03166176)
- Testing
- Vistusertib(AZD2014)
- Where
- South Korea
- Sponsor
- Samsung Medical Center