Clinical trials: sponsored by Samsung Medical Center
Gastric Adenocarcinoma
Single-arm Study of Selumetinib in Combination With Docetaxel, in Advanced Gastric Adenocarcinoma Patients With Low/High MEK Signature, RAS Mutation or RAS Amplification as a Second-line Chemotherapy
This study is a single-arm, phase II study of selumetinib in combination with docetaxel in patients with advanced gastric adenocarcinoma harboring MEK signature, RAS mutation or amplification as a second line chemotherapy.
- Trial name
- NCT02448290
- Testing
- docetaxel plus selumetinib
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Samsung Medical Center
Cancer of Stomach
Phase II Trial of AZD2014 in TSC1/2 Mutated or TSC1/2 Null GC Patients as Second-line Chemotherapy
Phase II trial of AZD2014 in TSC1/2 mutated or TSC1/2 null GC patients as second-line chemotherapy
- Trial name
- NCT03082833
- Testing
- AZD2014
- Where
- South Korea
- Volunteers
- 1 people
- Sponsor
- Samsung Medical Center
Gastric Cancer
Glycans Bound to Serum Haptoglobin: a Novel Gastric Cancer Tumor Biomarker
The purpose of this study is to evaluate sensitivity and specificity of newly defined tumor biomarker with gastric cancer pts and cancer-free healthy volunteers.
- Trial name
- NCT02848066
- Testing
- Blood sample(10cc) collection
- Where
- South Korea
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Colon Cancer
A Prospective Study of Pharmacogenetic Factors and Gene Expression Profile
This study is a parallel translational study of a Randomized Phase III trial Investigating the Role of Oxaliplatin duration (6 Cycles Versus 12 Cycles) in modified FOLFOX-6 Regimen as Adjuvant Therapy for Patients with Stage…
- Trial name
- NCT01472601
- Where
- South Korea
- Volunteers
- 2,660 people
- Sponsor
- Samsung Medical Center
Neuroendocrine Tumors
Study of Lanreotide in Metastatic or Recurrent Grade I-II Hindgut NET
Clinical data from uncontrolled retrospective or prospective studies have initially demonstrated antiproliferative effects of lanreotide in limited number of patients lanreotide Autogel® has recently been approved in more than 40…
- Trial name
- NCT03083210
- Testing
- Lanreotide
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Solid Tumor
Phase II Trial of AZD2014 in RICTOR Amplified Solid Cancer Patients Refractory to Standard Chemotherapy
Patients with RICTOR amplified refractory solid cancer will receive vistusertib(AZD2014). Study-arm is composed of 27 patients. Vistusertib(AZD2014) 50mg BD continuous schedule of a 28 day cycle Tumour evaluation using RECIST 1.1…
- Trial name
- RICTOR_SC (NCT03166904)
- Testing
- Vistusertib(AZD2014)
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Gastric Cancer
Circulating Free DNA Analysis in Gastrointestinal Cancer, Genitourinary Cancer, Rare Cancer
The investigators planned this study to Patients with histologically confirmed metastatic gastrointestinal cancer, genitourinary cancer , rare cancer with treated any anti-cancer therapy : Extra blood sample collection during…
- Trial name
- NCT02067754
- Where
- South Korea
- Volunteers
- 396 people
- Sponsor
- Samsung Medical Center
Coronary Bifurcation Lesion
Korean Coronary Bifurcation Stenting (COBIS) Registry III
The COBIS III registry is a multi-center, real-world registry of 2nd generation drug-eluting stenting in coronary bifurcation lesions in South Korea.
- Trial name
- COBIS III (NCT03068494)
- Where
- South Korea
- Volunteers
- 2,648 people
- Sponsor
- Samsung Medical Center
Stroke, Healthy
The Effect of a Walking Assist Robot on Gait Function and Brain Activity in Stroke Patients and Elderly Adults
The purpose of this study was to investigate the effects of the new wearable hip assist robot, gait enhancing and motivating system (GEMS) developed by Samsung Advanced Institute of Technology (Samsung Electronics Co, Ltd.…
- Trial name
- NCT03048968
- Testing
- Gait, sit-to-stand movement, stair climbing and treadmill gait, Sit-to-stand movement and treadmill gait, gait enhancing mechatronic system (GEMS)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Pancreatic Cancer
Circulating Cell-free Tumor DNA(ctDNA) in Pancreatic Cancer
The aim of the study is to evaluate whether peripheral circulating cell-free tumor DNA(ctDNA) can help early screening of pancreatic cancer recurrence or not.
- Trial name
- NCT02934984
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Deficiency of Anterior Cruciate Ligament
Development of Novel Strategy for Treatment of Anterior Cruciate Ligament (ACL) Injury Using Stem Cell
Purpose:Development of novel strategy for treatment of anterior cruciate ligament (ACL) injury using stem cell.
- Trial name
- NCT02755376
- Testing
- Cartistem(TM), hyaluronic acid, ACL reconstruction only
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Stroke, Healthy
Gait Pattern Analysis and Feasibility of Gait Training With a Walking Assist Robot in Stroke Patients and Elderly Adults
The purpose of this study was to investigate the effects of the new wearable hip assist robot developed by Samsung Advanced Institute of Technology (Samsung Electronics Co, Ltd., Korea) to gait rehabilitation in elderly adults…
- Trial name
- NCT02843828
- Testing
- gait rehabilitation with Samsung Hip Assist v1, gait rehabilitation without Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Migraine
Prediction of WMH in Migraine Using a BOLD-CVR Map
Brain white matter hyperintensities (WMHs) are prevalent in migraineurs, of which the mechanism is still unclear. The investigators aimed to test the spatial association between areas with reduced cerebrovascular reactivity (CVR)…
- Trial name
- NCT03494673
- Testing
- BOLD MRI
- Where
- South Korea
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Bronchopulmonary Dysplasia
Follow-Up Study of Safety and Efficacy of Pneumostem® in Premature Infants With Bronchopulmonary Dysplasia
This is a long term follow-up study of the open label, single-center, phase I clinical trial to evaluate the safety of Pneumostem® in premature infants with BPD.
- Trial name
- NCT01632475
- Testing
- Pneumostem®
- Where
- 2 sites in South Korea
- Volunteers
- 9 people
- Sponsor
- Samsung Medical Center
Intracranial Hemorrhages, Mesenchymal Stem Cells
Follow-Up Study of Safety of Pneumostem® in Premature Infants With Intraventricular Hemorrhage
This is a follow-up study of the open label, single-center, phase I clinical trial to evaluate the safety of Pneumostem® in premature infants with Intraventricular hemorrhage.
- Conditions
- Intracranial Hemorrhages, Mesenchymal Stem Cells, Newborn Infant
- Trial name
- NCT02673788
- Testing
- observation without intervention in this follow up study
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Samsung Medical Center
Metastatic Breast Cancer
A Study of Palbociclib With Exemestane Plus GnRH Versus Capecitabine in Premenopausal Women With HR+ MBC
Despite recent advances for the treatment of post-menopausal hormone receptor-positive BC, in the last decade there was no major improvement of hormonal therapy specifically for premenopausal metastatic breast cancer.
- Trial name
- NCT02592746
- Testing
- Palbociclib, Exemestane, Leuprolide Acetate
- Where
- 2 sites in South Korea
- Volunteers
- 182 people
- Sponsor
- Samsung Medical Center
Diabetes Mellitus, Insulin Hypoglycemia
Information and Communication Technology Based Centralized Clinical Trial Monitoring System for Insulin Dose Adjustment
This is a 24-week, open-label, randomized, multi-center trial conducted in three tertiary hospitals. There are three follow-up measures; at baseline, post-intervention at Week 12, and Week 24.
- Conditions
- Diabetes Mellitus, Insulin Hypoglycemia, Insulin-dependent Diabetes Mellitus
- Trial name
- ICT (NCT03112343)
- Testing
- Algorithm-based feedback messages, Personal Health Record
- Where
- South Korea
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Coronary Artery Disease
Graft Patency Analysis of the Right Coronary Artery System
The ideal grafts for the right coronary artery system in coronary artery bypass surgery remain controversial. The objective of this study is to compare the long-term patency of a right gastroepiploic artery and a saphenous vein…
- Trial name
- NCT01559350
- Testing
- A right gastroepiploic artery in situ grafting, A saphenous vein grafting
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Cushing Syndrome
Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma
Objective: To determine the metabolic effects of the adrenalectomy in subclinical Cushing's syndrome of adrenal incidentaloma. Methods: 234 subclinical cushing syndrome and adrenal incidentaloma will be randomly assigned into two…
- Trial name
- NCT01382420
- Testing
- surgery
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Samsung Medical Center
Erythrocyte Transfusion, Percutaneous Coronary Intervention
The Long-term Clinical Outcomes and Patterns of Transfusion in PCI Patients: Retrospective Cohort Study
A nationwide retrospective cohort study. To investigate the long-term patterns of transfusion and clinical outcomes of patients undergoing PCI.
- Conditions
- Erythrocyte Transfusion, Percutaneous Coronary Intervention, Revascularization
- Trial name
- TFPCI (NCT03776266)
- Testing
- No intervention is required due to retrospective observational study
- Where
- South Korea
- Volunteers
- 48,786 people
- Sponsor
- Samsung Medical Center