Clinical trials: sponsored by Samsung Medical Center
Gastrectomy
Effect of the Mobile Self-input Tool of Incentive Spirometer (RCT)
This study evaluates the effectiveness of the mobile self-input tool providing alarm and visual motivation, how much more it can encourage practicing of incentive spirometer undergoing post-operative patients under general…
- Trial name
- NCT03569332
- Testing
- Alarm, Nurse's dashboard
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Samsung Medical Center
Previously Irradiated Recurrent Rectal Cancer
Concurrent Chemo-proton Radiotherapy With or Without Resection and Spacer Insertion for Loco-regional Recurrence of Previous Irradiated Rectal Cancer
The investigators conduct this study to evaluate the efficacy and adverse effect of salvage concurrent chemo-proton therapy (CCPT) with or without surgical resection in previously irradiated recurrent rectal cancer.
- Trial name
- RECCPT (NCT03098108)
- Testing
- Concurrent chemo-proton therapy
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Correction of Cancer-related Coagulopathy With Novel Oral Anticoagulant (Edoxaban)
Edoxaban for the Treatment of Coagulopathy in Patients With Active Cancer and Acute Ischemic Stroke: a Pilot Study. (ENCHASE Study)
Purpose: Cancer-related hypercoagulability plays an important role in the development of cancer-related stroke. With rapidly aging population and increasing cancer prevalence, cancer related stroke has become an important stroke…
- Trial name
- ENCHASE (NCT03570281)
- Testing
- Edoxaban, Enoxaparin
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Atrial Fibrillation
Safety and Effectiveness of Low Dose Edoxaban in Patients With NVAF
The efficacy and safety of edoxaban has not been adequately studied in Asians versus non-Asians, who are quite different physiologically from each other.
- Trial name
- LEDIOS (NCT03554837)
- Where
- South Korea
- Volunteers
- 2,562 people
- Sponsor
- Samsung Medical Center
Diabetes Mellitus, Type 2
Effects of Dietary Fiber on Glucose Control in Subjects With Type 2 Diabetes Mellitus
The purpose of this study is to determine the effect of a commercial dietary fiber supplement on patients with type 2 diabetes mellitus, in the way of glucose control, insulin action in the body, and the gut microbiota (bacteria)…
- Trial name
- NCT03552991
- Testing
- Agiocur Pregranules
- Volunteers
- 14 people
- Sponsor
- Samsung Medical Center
Breast Cancer
Early Rehabilitation After Immediate Reconstruction With TEI in Breast Cancer Patients
The purpose of the study is to find best post-operative rehabilitation protocol after total mastectomy and immediate reconstruction with tissue expander insertion.
- Trial name
- NCT03541161
- Where
- South Korea
- Volunteers
- 115 people
- Sponsor
- Samsung Medical Center
Catheterization, Peripheral
The Usefulness of Ultrasound Guided Technique Insertion of Radial Artery Catheter in Neonates and Infants
The investigators are trying to compare the ultrasound-guided technique vs. palpation method for radial arterial cannulation in infants.
- Trial name
- NCT02795468
- Testing
- Radial arterial cannulation
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center
Gait Disorders, Neurologic, Stroke
Effect of Gait Training With a Walking Assist Robot on Gait Function and Balance in Patients With Chronic Stroke
The purpose of this study was to investigate the effects of gait training with the new wearable hip assist robot developed by Samsung Advance Institute of Technology (Samsung Electronics Co, Ltd, Korea) in patients with chronic…
- Trial name
- NCT03326011
- Testing
- Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Samsung Medical Center
Gait, Unsteady, Healthy
Effect of Gait Training With a Walking Assist Robot on Gait Function and Balance in Elderly Adults
The purpose of this study was to investigate the effects of gait training with the new wearable hip assist robot developed by Samsung Advance Institute of Technology (Samsung Electronics Co, Ltd, Korea) in elderly adults.
- Trial name
- NCT03325998
- Testing
- Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Samsung Medical Center
Liver Neoplasm, Proton Therapy
Feasibility of High Dose PROton Therapy On Unresectable Primary Carcinoma Of Liver: Prospective Phase II Trial
The standard treatment of unresectable hepatocellular carcinoma (HCC) is transarterial chemoembolization (TACE) or sorafenib. Though the TACE and the agent showed survival benefit in several randomized phase III trials, the…
- Trial name
- NCT02632864
- Testing
- Proton arm
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Samsung Medical Center
Acromegaly Due to Pituitary Adenoma
Multicenter Evaluation of the Effect of Upfront Radiosurgery on Residual Growth Hormone-secreting Pituitary Adenoma
In this study, the investigators hypothesize that upfront gamma knife radiosurgery with drug therapy is superior in the treatment of growth hormone-secreting pituitary tumors after primary surgical treatment compared with the…
- Trial name
- MERGE (NCT03439709)
- Testing
- Gamma knife radiosurgery, Lanreotide 60Mg Solution for Injection
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Overactive Bladder
Prospective Study for Patient Perception of Treatment Satisfaction After Switching to Mirabegron in Patients With Overactive Bladder Who Were Unsatisfied With Efficacy of Antimuscarinic Therapy or Adverse Event.
The purpose of this study is to measure the treatment satisfaction after switching to mirabegron in patient with Overactive Bladder(OAB) who were unsatisfied with efficacy of antimuscarinic therapy or adverse event.
- Trial name
- NCT02468375
- Testing
- mirabegron 50mg
- Where
- South Korea
- Volunteers
- 434 people
- Sponsor
- Samsung Medical Center
Postoperative Pain, Thoracic Cancer
Ultrasound-guided Block for Thoracic Surgery Pain
The investigators aimed to assess Ultrasounde- guided serratus anterior plane block can be effective in acute postoperative pain following thoracic surgery.
- Trial name
- NCT03240562
- Testing
- serratus anterior plane block, patient controlled analgesia
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease
Rotational Atherectomy for Calcified lEsion By Smart Angioplasty Research Team (SMART-RACE)
Current guidelines recommend the use of rotational atherectomy (RA) for preparation of heavily calcified or severely fibrotic lesions that cannot be crossed by a balloon or adequately dilated before planned stenting (bailout…
- Trial name
- NCT02716363
- Testing
- Rotational Atherectomy by Rotablator
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Variant Angina
The Effect of Sarpogrelate and High Dose Statin on the Reduction of Coronary Spasm
The aim of the study was to to evaluate the effect of sarpogrelate, a selective serotonin receptor antagonist, and high dose statin on the reduction of coronary spasm in the patients with variant angina.
- Trial name
- NCT01674686
- Testing
- Sarpogrelate, Atorvastatin
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome
Safety of 6-month Duration of Dual Antiplatelet Therapy After Acute Coronary Syndromes (SMART-DATE)
1. Objective : To test the safety of 6 month-duration of dual antiplatelet therapy (DAPT) compared to conventional 12-month-or-longer duration after second-generation drug-eluting stent (DES) implantation in patients with acute…
- Trial name
- SMART-DATE (NCT01701453)
- Testing
- P2Y12 inhibitor (clopidogrel, ticagrelor, prasugrel)
- Where
- South Korea
- Volunteers
- 2,712 people
- Sponsor
- Samsung Medical Center
Non Small Cell Lung Cancer
Uncommon EGFR AZD9291
EGFR (ErbB1) mutations define a lung cancer subtype with exquisite sensitivity to EGFR tyrosine kinase inhibitors (TKIs). While in-frame deletion in exon 19 (Del19) and a point mutation (L858R) in exon 21 are the two most common…
- Trial name
- NCT03424759
- Testing
- AZD9291
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Samsung Medical Center
Breast Cancer
Genetic Alteration After Systemic Treatment in Breast Cancer
The purpose of this study is to investigate effects of systemic treatments on genomic profiles in patients with breast cancer and to compare genomic profiling between premenopausal and postmenopausal women by systemic treatments…
- Trial name
- NCT02591966
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
HER2-positive Gastric Cancer Patients With Liver Metastasis
Phase II Study of Neoadjuvant XELOX + Lapatinib in HER2(+) Gastric Cancer Patients With Liver Metastasis
We planned this study to investigate the efficacy and safety of XELOX (capecitabine and oxaliplatin) plus lapatinib treatment in HER2-positive gastric cancer patients with liver metastasis.
- Trial name
- NCT02015169
- Testing
- Lapatinib
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Samsung Medical Center
Aging
Evaluation of the Effects of the New Program for Cognitive Enhancement and Improvement in the Elderly
The purpose of this study is to investigate the effect of cognitive rehabilitation program on the improvement of cognitive functions in normal elderly subjects.
- Trial name
- NCT03401775
- Testing
- Cognitive rehabilitation program
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center