Clinical trials: sponsored by Samsung Medical Center
Atrial Fibrillation
Hybrid Procedure in Patients With Persistent Atrial Fibrillation
In this study, the investigators therefore comparatively analyzed the mid-term results (at 1 year) including electrocardiogram, 24 hour Holter monitoring, and 2 week long-term electrocardiogram of thoracoscopic ablation and RFCA…
- Trial name
- NCT02392338
- Testing
- Hybrid procedure
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Breastcancer, Surgery: Axillary Dissection
Anti-adhesive Effect and Safety of a Mixed Solid of Poloxamer, Gelatin and Chitosan(Mediclore®) After Axillary Dissection for Breast Cancer
Anti-adhesive effect and Safety of a mixed solid of poloxamer, gelatin and chitosan(Mediclore®) after axillary dissection for breast cancer
- Trial name
- NCT02967146
- Testing
- adhesive barrier
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Samsung Medical Center
Stress, Psychological, Motion Sickness
Research on Quantification of VR(Virtual Reality) Related Stress and Relaxation
Current virtual reality device makes motion sickness and visual fatigue having limitation for recreation and other clinical approaches.
- Conditions
- Stress, Psychological, Motion Sickness, Visual Fatigue
- Trial name
- NCT02986555
- Testing
- Existing Biofeedback, Biofeedback accompanied with virtual reality
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Major Depressive Disorder
Research on Pathophysiology and Treatment in Depression Using Brain Derived Neurotrophic Factor and Amyloid Neuroimaging
Target of the research Based on change of Brain-derived neurotrophic factor and other pro-inflammatory cytokine along with symptom improvement following treatment, the investigators are trying to find the new treatment target…
- Trial name
- NCT02983838
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
To Investigate the Prevalence of BRCA 1/2 Mutation Among Ovarian Cancer
BRCA 1/2 Mutation in Korean Patients With Epithelial Ovarian Cancer
PURPOSE: To investigate the prevalence and clinical correlation of the germline BRCA 1/2 mutation in Korean patients with high grade(HG) serous and/or endometrioid epithelial ovarian cancer (EOC).
- Trial name
- NCT02963688
- Testing
- Ion AmpliSeq BRCA 1/2 Panel (Life Technologies, Carlsbad, CA, USA) ,Ion PGM platform
- Volunteers
- 298 people
- Sponsor
- Samsung Medical Center
Neuroblastoma
Reduced Intensity Stem Cell Transplantation in Children With Relapsed Neuroblastoma After Autologous Transplantation
The purpose of this study is to evaluate the feasibility and efficacy of reduced-intensity allogeneic stem cell transplantation (RIST) with RIC regimen in children with neuroblastoma who have failed a prior autologous stem cell…
- Trial name
- NCT00793351
- Testing
- Reduced-intensity allogeneic hematopoietic stem cell transplantation
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Samsung Medical Center
Pediatric Cancer Patients
Registry for Analysis of Quality of Life, Normal Organ Toxicity and Survival of Pediatric Patients Treated With Proton Therapy
The study aim of this study is to evaluate the effect of proton therapy on quality of life and long-term normal tissue toxicities of the pediatric cancer patients.
- Trial name
- NCT02644993
- Testing
- Proton therapy
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Samsung Medical Center
Pulmonary Neoplasm, Pulmonary Tuberculosis
Could the Stroke Volume Variation Predict a Fluid Responsiveness in Thoracotomy?
There are some risks of pulmonary edema in patients undergoing pulmonary lobectomy with one lung ventilation. The overloading of fluid administration could be related to the development of pulmonary edema in patents after…
- Trial name
- NCT02331056
- Testing
- fluid loading, thoracoscopic pulmonary lobectomy, thoracotomy
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Samsung Medical Center
Breast Neoplasms
Selective Lymph Node Dissection Using Fluorescent Dye in Node-positive Breast Cancer
In this study, navigation of lymphatic passage after sentinel lymph node with indocyanine green was performed during axillary lymph node dissection in breast surgery .
- Trial name
- NCT02781259
- Testing
- Axillary lymph node dissection, Indocyanine green, Imaging devices
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Samsung Medical Center
Carcinoma. Hepatocellular
Effectiveness and Safety of the Simultaneous Radiotherapy and Hyperthermia After Transarterial Chemoembolization in Hepatocellular Carcinoma Patients Combined With Portal Vein Tumor Thrombosis
The presence of portal vein tumor thrombosis (PVTT)in patients with HCC is one of the most significant prognostic factors for poor prognosis, without treatment, their survival is less than 3 months.
- Trial name
- NCT01911000
- Testing
- RT and hyperthermia after TACE
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Samsung Medical Center
Renal Cell Carcinoma
Transperitoneal vs Retroperitoneal Laparoscopic or Robotic Partial Nephrectomy
Both laparoscopic partial nephrectomy (LPN) and robotic partial nephrectomy (RPN) can be performed through transperitoneal (TP) or retroperitoneal (RP) approach.
- Trial name
- NCT02849119
- Testing
- Laparoscopic or robotic partial nephrectomy
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Samsung Medical Center
Pediatric Acute Myeloid Leukemia
Optimal Treatment Strategy Based on for Pediatric AML
The purpose of this study is to optimize therapy according to the known risk factors and treatment response in pediatric acute myeloid leukemia (AML)
- Trial name
- NCT02848183
- Testing
- Cytarabine, Idarubicin, Mitoxantrone
- Where
- 3 sites in South Korea
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
Central Serous Chorioretinopathy, Polypoidal Choroidal Vasculopathy
Angiographic Characteristics of CSC, PCV Patients and Thrombotic Bio-markers
Thrombotic biomarkers and angiographic characteristics were compared among the de novo patients of central serous chorioretinopathy (CSC), polypoidal choroidal vasculopathy (PCV) and the control.
- Trial name
- NCT02815176
- Testing
- Blood sampling
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Coronary Artery Bypass Surgery, Acute Kidney Injury
Predicting Acute Kidney Injury After Coronary Artery Bypass Graft
Acute kidney injury after cardiac surgery is a major complication after cardiac surgery and has been reported to be associated with adverse outcome.
- Conditions
- Coronary Artery Bypass Surgery, Acute Kidney Injury, Creatinine, Mortality
- Trial name
- NCT02081261
- Testing
- Coronary artery bypass surgery
- Where
- South Korea
- Volunteers
- 877 people
- Sponsor
- Samsung Medical Center
Patients Undergoing Surgery for Congenital Heart Disease
Incidence, Risk Factors, and Risk Model of Acute Kidney Injury in Pediatric Patients Who Undergoing Surgery for Congenital Heart Disease
Acute kidney injury (AKI) is a major complication after cardiac surgery and has been reported to be associated with adverse outcome.
- Trial name
- NCT02081235
- Testing
- surgery for congenital heart disease
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Samsung Medical Center
Laryngopharyngeal Reflux Disease
Trial of Proton Pump Inhibitor With Prokinetics or Placebo in Patients With Laryngopharyngeal Reflux Disease
Based on meta-analysis of prokinetics trials in laryngopharyngeal reflux disease (LPRD) (Glicksman et al. 2014), well designed study was performed in 4 articles.
- Trial name
- NCT02533349
- Testing
- Motilitone, Pantoprazole
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Neurological Diseases or Conditions, Fluid Responsiveness
A Gray Zone Approach to Stroke Volume Variation Derived From NICOM
Optimal fluid management has been considered as crucial part to determine postoperative outcome and organ function. Recently developed, non invasive cardiac output measurement(NICOM, Cheetah Medical, Portland, OR)has enabled…
- Conditions
- Neurological Diseases or Conditions, Fluid Responsiveness, Non Invasive Cardiac Output Monitoring, Gray Zone
- Trial name
- NCT01898975
- Testing
- 500ml fluid loading
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Intracranial Germinoma
Chemotherapy Plus Reduced Radiotherapy in Intracranial Germinoma
The purpose of this study is to evaluate the outcome of intracranial germinoma treated with chemotherapy plus reduced radiotherapy.
- Trial name
- NCT02782754
- Testing
- Carboplatin, Etoposide, Cyclophosphamide
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Newly Diagnosed High Risk Neuroblastoma
Response-based Treatment of High-risk Neuroblastoma
The purpose of this study is to improve outcome of high risk neuroblastoma by tailoring the treatment intensity of tandem high dose chemotherapy according to the treatment response to induction chemotherapy.
- Trial name
- NCT02771743
- Testing
- Cisplatin, Doxorubicin, Etoposide
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Samsung Medical Center
Cerebrolysin
Effects of Cerebrolysin on Motor Recovery in Patients With Subacute Stroke
This study, E-COMPASS is a phase IV clinical trial designed as a multicenter, randomized, double-blind, placebo-controlled, parallel-group study.
- Trial name
- E-COMPASS (NCT01996761)
- Testing
- porcine brain peptide (Cerebrolysin)
- Where
- South Korea
- Volunteers
- 71 people
- Sponsor
- Samsung Medical Center