Clinical trials: sponsored by Samsung Medical Center
Liver Disease
Evaluation of EV1000™/volumeView™ for Cardiac Output Monitoring in Liver Transplantation
The investigators are trying to evaluate the agreement of cardiac output measurements taken using the specific thermistor-tipped arterial catheter ( the VolumeView ™ catheter) and the EV1000 ™ monitoring platform ( Edward…
- Trial name
- NCT02306018
- Testing
- EV1000™/volumeView™
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Samsung Medical Center
Pancreatic Neoplasms
Comparative Study of 22 and 25 Gauge ProCore EUS-guided Biopsy in Pancreatic Mass
Background: EUS-guided fine needle aspiration (FNA) is a major diagnostic tool in the patient with pancreatic mass with high specificity, specificity and accuracy.
- Trial name
- NCT01727921
- Testing
- 22 gauge ProCore needle biopsy, 25 gauge ProCore needle biopsy
- Where
- South Korea
- Volunteers
- 219 people
- Sponsor
- Samsung Medical Center
Tumor Appearance of Biliary System Obstruction
Prospective Study Comparing EUS vs ERCP Stent Insertion for Malignant Biliary Obstruction
1. Purpose of the study -To compare stent patency and complication rate between endoscopic ultrasound (EUS) guided stent insertion and endoscopic retrograde cholangiopancreatography (ERCP) guided stent insertion for malignant…
- Trial name
- NCT01421836
- Testing
- ERCP-guided stent insertion, EUS guided stent insertion
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Pancreatic Cancer
Comparing Newly Developed PreCore Needle With Conventional Fine Needle in Suspected Unresectable Pancreatic Cancer
Background: Pancreatic cancer is associated with a poor prognosis. Therefore, rapid and accurate diagnosis of a pancreatic mass is important to direct patient management.
- Trial name
- NCT01876069
- Testing
- 22 gauge ProCore needle aspiration, 22 gauge Fine needle aspiration
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Samsung Medical Center
Bile Duct Neoplasm, Obstructive Jaundice
Comparison Between Two Methods of Bilateral Stenting for Malignant Hilar Obstruction
Internal biliary drainage using stent is used for malignant hilar obstruction such as cholangiocarcinoma, hepatocellular carcinoma and other malignancy including metastasis.
- Trial name
- NCT01622803
- Testing
- parallel stent, Y-stent (BONASTENT M-Hilar)
- Where
- South Korea
- Sponsor
- Samsung Medical Center
NAT2 Genotype
Isoniazid Dosage Prediction Model Development
Isoniazid (INH) is an essential component of first-line anti-tuberculosis (TB) treatment. However, treatment with INH is complicated by polymorphisms in the expression of the enzyme system primarily responsible for its…
- Trial name
- NCT02747654
- Testing
- genotype
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Carcinoma
Extent of Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma
Occult lymph node metastasis is common in micro papillary thyroid cancer. However, the role of lymph node dissection in the treatment of microPTC remains controversial.
- Trial name
- NCT01149161
- Testing
- Routine central neck dissection
- Where
- South Korea
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Thyroid Neoplasm
Lateral Neck Sentinel Lymph Node Biopsy(LSLNB)in PTC
Objective: To investigate the incidence of lateral neck node occult metastasis and to show the usefulness of sentinel lymph node biopsy (SLNB) in the detection of lateral neck node metastasis in thyroid carcinoma, the…
- Trial name
- LSLNB (NCT01137097)
- Testing
- Lateral sentinel lymph node biopsy
- Where
- South Korea
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Locally Advanced Stage III or IV Thymic Cancer
Neoadjuvant Chemotherapy for Locally Advanced Thymic Cancer
We try to evaluate whether neoadjuvant docetaxel plus cisplatin can increase the complete resection rate in advanced thymic carcinoma.
- Trial name
- NCT01312324
- Testing
- neoadjuvant docetaxel/cisplatin
- Where
- South Korea
- Volunteers
- 27 people
- Sponsor
- Samsung Medical Center
Cancer, Stroke
Anticoagulation in Cancer Related Stroke
Purpose: Cancer associated intravascular coagulopathy is the primary mechanism of cancer-related stroke, particularly in those without conventional stroke etiologies.
- Trial name
- OASIS-CANCER (NCT02743052)
- Testing
- Anticoagulation treatment.
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Samsung Medical Center
Mantle Cell Lymphoma
Vorinostat Plus FND in Relapsed or Refractory Mantle Cell Lymphoma
1. Rationale In mantle cell lymphoma, the conventional chemotherapy achieves only temporary responses with a median duration of remissions only from 1 to 2 years.
- Trial name
- ZOLINZA (NCT01578343)
- Testing
- Fludarabine, Mitoxantrone, Dexamethasone, Vorinostat
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Thyroid Cancer
Prophylactic Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma
The purpose of this study is to determine whether the prophylactic ipsilateral central lymph node dissection is equally effective in the management of papillary thyroid microcarcinoma(PTMC) to the bilateral central lymph node…
- Trial name
- NCT00795782
- Testing
- Prophylactic central lymph node dissection
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Samsung Medical Center
Gastric Cancer
A Study of Pazopanib With CAPEOX in AGC Patients
In order to improve survival of metastatic gastric cancer patients, we plan to to conduct a phase II trial of CapeOx with 800 mg once-daily pazopanib as a first-line chemotherapy in metastatic gastric cancer patients.
- Trial name
- NCT01130805
- Testing
- Pazopanib in combination with capecitabine and oxaliplatin
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Samsung Medical Center
Chronic Renal Failure
The Impact of Early Protocol Biopsy in Kidney Transplant
The purpose of this study is evaluating the impact of steroid pulse therapy (SPT) on SCR revealed on PB in KT recipients maintained on TAC/MMF and corticosteroid.
- Trial name
- NCT02733510
- Testing
- methylprednisolone
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Chronic Renal Failure
The Effect of Steroid Pulse Therapy for the Reduction of Acute Rejection Episode in Subclinical Borderline Changes
Several studies have shown that about 30% of transplanted kidneys with stable function present with tubule-interstitial mononuclear cell infiltration in protocol biopsies and therefore meet criteria for acute rejection.
- Trial name
- NCT02664493
- Testing
- Methylprednisolone
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Samsung Medical Center
Gynecologic Neoplasms, Abdominal Neoplasms
Augmented Pulse Pressure Variation to Predict Fluid Responsiveness in Open Laparotomy
Pulse pressure variation (PPV) is a well-known and widely used dynamic preload indicator based on heart-lung interaction to predict fluid responsiveness.
- Trial name
- NCT02653469
- Testing
- Augmented ventilation, Fluid loading
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Samsung Medical Center
Circadian Rhythm Phase Shift
A Study on the Changes of the Biological Rhythm by Display Image Modulation
Effects of Smartphone Use at Night with Light Emitting Diode Display With and Without Blue Light in Healthy Adults: A Randomized, Double-blind, Cross-over, Placebo-controlled Comparison
- Trial name
- NCT02690311
- Testing
- smartphone display
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Major Depressive Disorder, Anxiety Disorder
The Development of Skin Adhesive Patches for the Monitoring and Prediction of Mental Disorders
development of skin adhesive patches for the monitoring and prediction of mental disorders
- Trial name
- NCT02690324
- Testing
- cognitive stress (serial 7)
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
The Lamina Cribrosa and Optic Nerve Head Changes
The Lamina Cribrosa (LC) Changes in the Eyes After Laser-Assisted in Situ Keratomileusis (LASIK)
The burden of LASIK surgery on optic nerve head (ONH) has been controversial. Until now, the change of retinal nerve fiber layer (RNFL) thickness was used as the indicator of the study.
- Trial name
- NCT02676557
- Testing
- Exposed to the high pressure during the surgery
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Macular Holes
Extent of ILM Removal and Its Impact on Outcomes of MH Surgery
Eligible patients who were scheduled for surgery for idiopathic macular hole (MH) were equally randomized to small extent group or large extent group depending on the extent of internal limiting membrane (ILM) to be removed.
- Trial name
- NCT02010138
- Testing
- small-extent peeling, large-extent peeling
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Samsung Medical Center