Clinical trials: sponsored by Samsung Medical Center
Hepatocellular Carcinoma
to Evaluate the Efficacy and Safety of MG4101(Ex Vivo Expanded Allogeneic NK Cell)
To see the safety and efficacy of injecting MG4101 as a secondary treatment after curative liver resection on the patient with advanced HCC who has high risk of recurrence.
- Trial name
- MG4101 (NCT02008929)
- Testing
- MG4101
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Samsung Medical Center
Recurrent or Metastatic Salivary Gland Cancer of the Head and Neck
Trial of BIBF1120 (Nintedanib) in Patients With Recurrent or Metastatic Salivary Gland Cancer of the Head and Neck
Recently, sorafenib which can target VEGFR and PDGFR demonstrated 13-16% of response rate in patients with recurrent/metastatic salivary gland cancers, suggesting that VEGFR and PDGFR might be important role in salivary gland…
- Trial name
- NCT02558387
- Testing
- BIBF1120
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Lung Cancer
Feasibility of Mutational Analysis of Non-Small Cell Lung Cancer (NSCLC) Using Low-volume Lung Aspirates
The purpose of this study is to evaluate the feasibility of aspiration samples for mutational analysis in patients with a non-small cell lung cancer (NSCLC).
- Trial name
- NCT01482572
- Testing
- biopsy
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Hepatocellular Carcinoma, Obstructive Jaundice
Safety and Efficacy of Photodynamic Therapy for Bile Duct Invasion of Hepatocellular Carcinoma
The prognosis of patients with obstructive jaundice caused by hepatocellular carcinoma (HCC) is dismal even after biliary drainage; due to malfunction of the biliary drainage tube caused by hemobilia and/or tumor emboli.
- Trial name
- NCT01506115
- Testing
- Photofrin
- Where
- South Korea
- Volunteers
- 11 people
- Sponsor
- Samsung Medical Center
Non-small Cell Lung Cancer
Predictive Value of FDG PET/CT, DWI and DCE-MRI Scans for Non-small Cell Lung Cancer Patients Receiving Chemotherapy
In this prospective study, the investigators will evaluate and compare the usefulness of functional and volumetric informations obtained by 18F-FDG PET and MRI before and after the palliative chemotherapy with the aim of…
- Trial name
- NCT01482182
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Samsung Medical Center
Type 1 Diabetes
The Effect of Online Based Mentoring Program on the Blood Glucose and Satisfaction Score in Type 1 Diabetes Patients
Purpose: To evaluate the effects of online based mentoring program on the blood glucose and satisfaction score in type 1 diabetes patients. Peer group mentoring will be as effective as guidance by the doctors.
- Trial name
- NCT01157611
- Testing
- Mentoring program
- Where
- South Korea
- Volunteers
- 57 people
- Sponsor
- Samsung Medical Center
Surgery for Congenital Heart Disease, Pediatric Patients
The Predictability of Intraoperative Rotational Thromboelastometry on Postoperative Bleeding and Transfusion Requirements
Viscoelastic hemostatic assay has been reported to be superior to predict perioperative bleeding in cardiac surgical patients compared with conventional blood coagulation test.
- Trial name
- NCT02081222
- Testing
- surgery for congenital heart disease with cardiopulmonary bypass
- Where
- South Korea
- Volunteers
- 119 people
- Sponsor
- Samsung Medical Center
Hemophagocytosis
Retrospective Analysis for Patients With Hemophagocytosis in Bone Marrow
Comparison of malignant and non-malignant disorders associated bone marrow hemophagocytosis.
- Trial name
- NCT02401932
- Testing
- Hemophagocytosis
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Samsung Medical Center
Carcinoma of Unknown Primary
Phase 2 Study of Gemcitabine and Docetaxel Combination Chemotherapy in Patients With Carcinoma of Unknown Primary
It's a phase 2, single arm study of gemcitabine an docetaxel combination in patients with carcinoma of unknown primary.
- Trial name
- NCT02590055
- Testing
- gemcitabine/docetaxel combination
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Bleeding, Transfusion Related Complication
Use of Transexamic Acid in Hip Replacement
Studies have shown that tranexamic acid reduces blood loss and transfusion need in patients undergoing total hip arthroplasty. However, no to date, no study has been large enough to determine definitively whether the drug is safe…
- Trial name
- NCT02587845
- Testing
- Tranexamic Acid (IV), Tranexamic Acid (Topical)
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Chest Pain, Severe Aortic Stenosis
Myocardial Flow Reserve in Severe AS Without Obstructive Coronary Artery Disease
Exertional angina is common symptom in patients with severe aortic stenosis (AS) without obstructive coronary artery disease (CAD).
- Trial name
- NCT02575768
- Testing
- Adenosine-stress cardiac magnetic resonance imaging
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Cardiac Surgical Procedures, Thoracic Surgical Procedures
Pulse Pressure Variation Measured During Valsalva Maneuver to Predict Fluid Responsiveness Under Open-chest Condition
Pulse pressure variation (PPV) is a well-known dynamic preload indicator to predict fluid responsiveness. However, its usefulness in open-chest conditions has been equivocal.
- Conditions
- Cardiac Surgical Procedures, Thoracic Surgical Procedures, Sternotomy
- Trial name
- NCT02457572
- Testing
- Valsalva maneuver, Fluid loading
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Samsung Medical Center
Renal Function, Liver Transplantation
Incidence, Risk Factors, and Risk Model of Acute Kidney Injury After Liver Transplantation
The incidence of acute kidney injury after liver transplantation has been reported to be 17 to 95 percent, but no definite treatment has been reported yet.
- Trial name
- NCT02080065
- Testing
- living donor liver transplantation
- Where
- South Korea
- Volunteers
- 573 people
- Sponsor
- Samsung Medical Center
Liver Neoplasms
A New Track Ablation Device for Liver Biopsy: A Feasibility Study
The purpose of this study is to evaluate the effectiveness and safety of a new biopsy track ablation device for liver biopsy.
- Trial name
- NCT02521129
- Testing
- Biopsy Track Ablator (STARmed, Goyang, Korea)
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Coronary Syndrome
The Effect of Rosuvastatin and Olmesartan on the Progression of Coronary Atherosclerotic Disease
1. Stains have demonstrated consistent benefits to reduce cardiovascular events in several primary and secondary prevention trials.
- Trial name
- NCT02516826
- Testing
- Rosuvastatin, Olmesartan, Combination
- Where
- South Korea
- Volunteers
- 504 people
- Sponsor
- Samsung Medical Center
Fluid Responsiveness, Prone Position
Evaluation of SVV From NICOM as a Predictor of Fluid Responsiveness in Prone Position During Spine Surgery
NICOM® is a recently developed noninvasive cardiac output monitoring device, and indices derived from NICOM® such as SVV has been reported to predict fluid responsiveness in the previous studies.
- Conditions
- Fluid Responsiveness, Prone Position, Non Invasive Cardiac Output Monitoring
- Trial name
- NCT02277353
- Testing
- Fluid loading to evaluate fluid responsiveness
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Hepatocellular Carcinoma, Liver Disease
Change of Lactate Concentration During Hartmann Solution Infusion for Hepatic Resection
The investigators are trying to investigate metabolism of lactate sourced from IV Hartmann's solution in patients with hepatocellular carcinoma(HCC) compared with a control group(donation for liver transplantation) with normal…
- Trial name
- NCT02329821
- Testing
- hartmann solution
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Samsung Medical Center
Ileus
Thoracic Epidural for Postoperative Ileus
The investigators try to find whether thoracic epidural analgesia (TEA) shortens the first gas-out time compared to iv-PCA and promotes earlier discharge after major upper abdominal surgery.
- Trial name
- NCT02491385
- Testing
- thoracic epidural analgesia, iv-PCA
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Samsung Medical Center
Attention Deficit Hyperactivity Disorder
EAA/Therapy for Treating Children With ADHD
The aim of this study is 1) to investigate clinical effects of equine-assisted activities and therapy (EAA/T) for treating attention-deficit/hyperactivity disorder (ADHD) and 2) to compare the clinical effect of EAA/T and drug…
- Trial name
- NCT02482649
- Testing
- EAA/T, Methylphenidate, Atomoxetine
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Samsung Medical Center
Carcinoma, Non-Small-Cell Lung
Efficacy Study of Additional Chemotherapy After Concurrent Chemoradiation in Non-small Cell Lung Cancer
Non-Small Cell Lung Cancer(NSCLC) is the leading cause of death in Korean men after stomach cancer. Surgical resection plays a main role for curative treatment.
- Trial name
- NCT00326378
- Testing
- consolidation chemotherapy with Docetaxel plus cisplatin, CCRT arm without consolidation chemotherapy
- Where
- South Korea
- Volunteers
- 434 people
- Sponsor
- Samsung Medical Center