Clinical trials: sponsored by Samsung Medical Center
Gastric Cancer
A Phase II Clinical Trial of Reduced Port Totally Laparoscopic Distal Gastrectomy With D2 Lymph Node Dissection
The purpose of this study is to determine if reduced port totally laparoscopic distal gastrectomy with complete D2 lymph node dissection for gastric cancer is safe and oncological feasible.
- Trial name
- NCT02311595
- Testing
- reduced port laparoscopic distal gastrectomy
- Volunteers
- 67 people
- Sponsor
- Samsung Medical Center
Hepatocellular Carcinoma, Portal Vein Tumor Thrombosis
Transarterial Chemoembolization (TACE) With Radiation Therapy (RT) in Advanced Hepatocellular Carcinoma (HCC)
The presence of portal vein tumor thrombosis (PVTT) in patients with hepatocellular carcinoma (HCC) is one of the most significant prognostic factors for poor prognosis, without treatment, their survival is less than 3 months.
- Trial name
- NCT02290977
- Testing
- Scheduled interval TACE - RT
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Carcinoma, Hepatocellular
Prompt Or Watchful Monitoring for Hepatitis B Virus Related Hepatocellular Carcinoma Without Elevated viRal Load
Antiviral therapy for HBV may play an important role here, as a large observation study from Taiwan reported that the use of nucleos(t)ide analogues (NUC) was associated with 33% reduction in HCC recurrence.
- Trial name
- POWER (NCT02308319)
- Testing
- Tenofovir disoproxil fumarate
- Volunteers
- 124 people
- Sponsor
- Samsung Medical Center
Spinal Cord Compression
Spine Stereotactic Body Radiation Therapy for Metastatic Epidural Spinal Cord Compression
Metastatic epidural spinal cord compression (MESCC) is a frequent oncologic emergency that requires to be treated promptly. Although direct decompressive surgery is the most effective treatment, surgery is only used in selected…
- Trial name
- NCT01826058
- Testing
- Stereotactic body radiation therapy
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Samsung Medical Center
Dyspepsia
Efficacy of Motilitone on Gastric Emptying in Patients With Functional Dyspepsia: Evaluation Using MRI Method
Functional dyspepsia (FD) is a disorder characterized by chronic or recurrent upper abdominal pain or discomfort in the absence of a specific structural cause.1 Several mechanisms have been suggested to underlie dyspeptic…
- Trial name
- NCT02151708
- Testing
- motilitone
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Samsung Medical Center
Hypothermia
Pre-warmed Intravenous Fluids and Monitored Anesthesia Care
The aim of the study is to compare effect of pre-warmed intravenous fluids on the early outcomes in ambulatory patients undergoing monitored anesthesia care.
- Trial name
- NCT01722955
- Testing
- Pre-warmed fluids, Room temperature fluids
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Heart Rate Variability, STAI
Perioperative Changes of Heart Rate Variability Related to Anxiety and Depressiveness in Patients Undergoing General Anesthesia
Preoperative anxiety can be detected via structured and standardised screening by the State - Trait Anxiety Inventory (STAI) and Self rating Depression Scale (SDS) questionnaire.
- Conditions
- Heart Rate Variability, STAI, SDS, General Anesthesia
- Trial name
- NCT02011074
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Myofascial Pain Syndrome
Hyaluronidase for Trigger Point Injection in Myofascial Pain Syndrome
Myofascial pain syndrome (MPS) is the most common cause of persistent regional pain characterized by myofascial trigger points. Trigger point injection (TPI) using local anesthetics is one of the most effective methods for…
- Trial name
- NCT02293083
- Testing
- trigger point injection
- Volunteers
- 61 people
- Sponsor
- Samsung Medical Center
Endotracheal Intubation, Infants or Young Children
Verification of Appropriate Insertion Depth of Endotracheal Tube Placement
The investigators are trying to evaluate the efficacy of ultrasonographic determination of depth of endotracheal tube placement in infants and young children by using the pleural sliding sign.
- Trial name
- NCT01628978
- Testing
- determination by auscultation, determination by ultrasound
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Breast Cancer
Whole Breast RT on Prone Position in Korean Women
It is well known fact that postoperative whole breast radiation therapy (RT) in left breast cancer patient can cause cardiac problem according to the exposed dose.
- Trial name
- NCT02231112
- Testing
- Whole breast RT on prone position
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Hepatocellular Carcinoma, Spine Metastasis
Diffusion-Weighted Magnetic Resonance Imaging
Recently, diffusion-weighted (DW) MR imaging has widened its application on various oncologic applications. Especially, it is expected the DW MRI could provide valuable information about early response evaluation after treatment…
- Trial name
- NCT02242786
- Testing
- External beam radiation therapy
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Samsung Medical Center
Spinal Anesthesia, Success or Failure of Spinal Anesthesia
The Influence of Body-mass Index on the Outcome of Spinal Anesthesia for Total Knee Replacement Arthroplasty
In these prospective observational study, the investigators are trying to evaluate (1) the influence of body-mass index on spinal anesthetic outcome and (2) the determinants on spinal anesthetic outcome by logistic regression…
- Trial name
- NCT01609517
- Testing
- Spinal anesthesia (heavy bupivacaine)
- Where
- South Korea
- Volunteers
- 209 people
- Sponsor
- Samsung Medical Center
Unstable Angina, Coronary Artery Bypass Graft
Comparison Between Lidocaine, Dexmedetomidine, and Their Combined Infusion in Subjects Undergoing Coronary Artery Bypass Graft
The aim of the present study is to compare the antiarrhythmic and myocardial protective effect between lidocaine, dexmedetomidine, and their combined infusion in subjects undergoing coronary artery bypass graft.
- Conditions
- Unstable Angina, Coronary Artery Bypass Graft, Dexmedetomidine, Lidocaine
- Trial name
- NCT01688648
- Testing
- Lidocaine infusion, Dexmedetomidine infusion
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Samsung Medical Center
Chronic Renal Disease
Kidney Graft Function Under the Immunosuppression Strategies
To demonstrate that cyclosporine-sparing immunosuppressions with the standard dose of Enteric-Coated Mycophenolate Sodium would preserve renal graft function after transplantation without an increase of incidences of adverse…
- Trial name
- MyLowCsA (NCT01817322)
- Testing
- Standard Dose of Myfortic and Reduced Dose of Myfortic, Prednisolone OR methylprednisolone OR deflazacort injected both control group and experimental group, Basiliximab injected both control group and experimental group
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Alzheimer's Disease
A Pilot Study of tDCS for Mild to Moderate Alzhemier's Disease
The primary objective of this preliminary study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Alzheimer's disease
- Trial name
- NCT02227953
- Testing
- Yband (YDT-201N)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Mild Cognitive Impairment
A Pilot Study of tDCS for Mild Cognitive Impairment
The primary objective of this preliminary study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Mild Cognitive Impairment (MCI)
- Trial name
- NCT02227966
- Testing
- Yband (YDT-201N)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Off Pump Coronary Artery Bypass Graft
Volatile Versus Propofol Anesthesia in OPCAB
Off pump coronary artery bypass graft (OPCAB) still requires myocardial protection owing to intermittent regional ischemic episode.
- Trial name
- NCT02222142
- Testing
- Isoflurane
- Where
- South Korea
- Volunteers
- 1,080 people
- Sponsor
- Samsung Medical Center
Pancreatic Neoplasms
Randomized, Controlled Trial of Endoscopic Ultrasound-Guided Bilateral Celiac Plexus Neurolysis vs Celiac Ganglia Neurolysis to Control Pain in Inoperable Pancreatic Cancer Patients With Inadequate Pain Control by Pain Killer
Pancreatic cancer related pain can be difficult to control, even with high doses of narcotics, whose adverse effects may further impair quality of life.
- Trial name
- NCT02220062
- Testing
- EUS-CPN, EUS-CGN
- Volunteers
- 166 people
- Sponsor
- Samsung Medical Center
End Stage Renal Disease
Tolerance Induction in Living Donor Kidney Transplantation With Hematopoietic Stem Cell Transplantation
Kidney transplantation (KT) requires a life-long immune suppression (IS). It has been well-known that long-term IS inevitably causes various complication e.g.
- Trial name
- NCT02199301
- Testing
- Transplantation Conditioning for BMT
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- Samsung Medical Center
General Anesthesia, Total Intravenous Anesthesia
Predicting Bispectral Index Values by Estimated Effect-site Concentration of Propofol and Remifentanil Displayed on the Target-centered Infusion Pump
The BIS is influenced by multiple parameters, such as age,gender, body weight, height, muscle relaxants, hepatic function, co-administered drugs, surgical stimulation, but is thought to be influenced mainly by propofol and…
- Conditions
- General Anesthesia, Total Intravenous Anesthesia, Bispectral Index Monitoring
- Trial name
- NCT01604226
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center