Clinical trials: sponsored by Samsung Medical Center
Coronary Artery Bypass Graft, Median Sternotomy
Risk Factors of Sternal Wound Infection After Coronary Artery Bypass Graft
The investigators are trying to evaluate the performance of neutrophil and lymphocyte counts as a risk factor of deep sternal wound infection after coronary artery bypass graft surgery.
- Trial name
- NCT01629030
- Where
- South Korea
- Volunteers
- 1,850 people
- Sponsor
- Samsung Medical Center
Biliary Tract Cancer
Phase II Study of Gemcitabine and TS-1 in Biliary Trat Cancer
In current study, we evaluate the efficacy of gemcitabine and TS-1 combination chemotherapy in advanced BTC.
- Trial name
- GetBil (NCT01171755)
- Testing
- Gemcitabine TS-1
- Volunteers
- 19 people
- Sponsor
- Samsung Medical Center
Breast Neoplasms
Perioperative Inflammation and Breast Cancer Outcome
It is increasingly recognized the NSAIDS (nonsteroidal antiinflammatory drug) might prevent the several cancers. In breast cancer, the role of NSAIDS (nonsteroidal antiinflammatory drug) has been suggested.However, there was no…
- Trial name
- NCT02141139
- Testing
- NSAIDS (ketorolac and ibuprofen)
- Where
- South Korea
- Volunteers
- 1,568 people
- Sponsor
- Samsung Medical Center
Gastroesophageal Reflux Disease
The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERD
PPI test;empirical trial with high-dose proton-pump inhibitors (PPIs) has been shown to be a sensitive tool for diagnosing patients with GERD.
- Trial name
- NCT00539786
- Testing
- Proton pump inhibitor (rabeprazole)
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Bladder Cancer
Salvage Docetaxel for Pretreated Urothelial Cancer
Based on the previous clinical experience in other cancers, and considering the absence of current standard salvage regimens, the single agent docetaxel is selected as the regimen for this phase II study.
- Trial name
- NCT01711112
- Testing
- Docetaxel
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Samsung Medical Center
Unresectable, Metastatic Biliary Tract Carcinoma
Gemcitabine/Oxaliplatin (GEMOX) With or Without Erlotinib (Tarceva) in Advanced Biliary Tract Carcinoma
The purpose of this study is to determine whether Gemcitabine/Oxaliplatin (GEMOX) with or without Erlotinib (Tarceva) is effective in the treatment of unresectable, metastatic biliary tract carcinoma.
- Trial name
- NCT01149122
- Testing
- Gemcitabine/Oxaliplatin, Gemcitabine/Oxaliplatin with Erlotinib (Tarceva)
- Where
- South Korea
- Volunteers
- 266 people
- Sponsor
- Samsung Medical Center
Hepatocellular Carcinoma, Renal Cell Carcinoma
Genome-wide Association Study to Predict Treatment Response for Molecular Targeted Therapy in Hepatocellular Carcinoma and Renal Cell Carcinoma
All Hepatocellular carcinoma and Renal cell carcinoma patients who receive molecular targeted therapy will be candidates for the study.
- Trial name
- NCT01482520
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Advanced Biliary Tract Adenocarcinoma
Sunitinib as Second-line Treatment in Advanced Biliary Tract Carcinoma
The purpose of this study is to determine whether sunitinib as second-line treatment in advanced biliary tract carcinoma
- Trial name
- NCT01082809
- Testing
- Sunitinib
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Samsung Medical Center
Polymorphism, CYP19
Aromatase (CYP19) Polymorphism Between AI-responsive and AI-resistant Breast Cancer in Korea
Aromatase(CYP19)inhibitor is one of the major antihormonal drug for breast cancer in postmenopausal women. The variation of CYP19 may affect the effect of aromatase inhibitor.
- Conditions
- Polymorphism, CYP19, Aromatase Inhibitor
- Trial name
- CYP19 (NCT01137136)
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Difficult Laryngoscopy
Evaluation of Clinical Airway Assessments With a Gray Zone Approach
Failure of advanced airway security has been reported that it could lead lethal complication such as brain hypoxic damage. There have been controversial reports for the airway assessment tests which can predict difficult…
- Trial name
- NCT01719848
- Testing
- Measurements of parameters related with physical examinations for difficult airway prediction
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Microvascular Angina
Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image
Current therapeutic options for a well-recognized group of patients with anginal symptoms-a positive exercise tolerance testing, SPECT or perfusion defect in MRI but angiographically normal coronary arteries-are limited.
- Trial name
- UMPIRE (NCT01769482)
- Testing
- Udenafil
- Where
- 2 sites in South Korea
- Volunteers
- 70 people
- Sponsor
- Samsung Medical Center
Diabetes
Comparison of New-onset Diabetes After Transplantation Between Two Steroid Withdrawal Group With CellCept
With improvements in patient and graft survival, increasing attention has been placed on complications that contribute to long-term patient morbidity and mortality.
- Trial name
- NODAT (NCT02095418)
- Testing
- Mycophenolate mofetil, Corticosteroids, Corticosteroids, Mycophenolate mofetil
- Where
- 5 sites in South Korea
- Volunteers
- 152 people
- Sponsor
- Samsung Medical Center
Multiple Myeloma
Oligosecretary Myeloma: Prevalence and Its Clinical Significance
In this study, the investigators aim to investigate the prevalence and clinical course of oligosecretary myeloma.
- Trial name
- NCT02095379
- Testing
- oligosecretary
- Where
- South Korea
- Volunteers
- 390 people
- Sponsor
- Samsung Medical Center
Dyspepsia
Efficacy of Motilitone on Gastric Accommodation in Healthy Adult Patients: Evaluation Using MRI Method
Functional dyspepsia (FD) is a disorder characterized by chronic or recurrent upper abdominal pain or discomfort in the absence of a specific structural cause.
- Trial name
- NCT02091635
- Testing
- Motilitone
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Macular Hole With High Myopia (Spherical Equivalent ≤ -6.0 Diopters) or,, Large Size Macular Hole (Diameter > 600 Microns) or
The Intravitreal Autologous Platelet Concentrate Injection as an Adjunct of Vitrectomy for the Treatment of Refractory Macular Holes
The purpose of this study is to determine the effectiveness of intravitreal autologous platelet concentrate (APC) injection during the surgery for refractory macular holes.
- Conditions
- Macular Hole With High Myopia (Spherical Equivalent ≤ -6.0 Diopters) or,, Large Size Macular Hole (Diameter > 600 Microns) or, Recurred or Failed Macular Hole From Previous Surgery, or Chronic Macular Hole (Symptom Duration > 6 Months)
- Trial name
- NCT02081170
- Testing
- Autologous platelet concentrate
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Samsung Medical Center
NSCLC
Afatinib Plus Nimotuzumb for NSCLC
To find the optimal dose of afatinib and nimotuzumab in patients who acquired resistance to gefitinib or erlotinib.
- Trial name
- NCT01861223
- Testing
- afatinib (30 or 40mg) + nimotuzumab (100 or 200mg)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Myelodysplastic Syndrome
Prognostic Molecular Markers in Patients With Myelodysplastic Syndrome
In the era of hypomethylating agent in MDS treatment, the investigators aimed to investigate the prognostic impact of mutations in spliceosome machinery genes (SRSF2, U2AF1, and ZRSR2) on the outcomes of 1st line decitabine…
- Trial name
- NCT02060409
- Testing
- spliceosome
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Samsung Medical Center
Diffuse Large B-cell Lymphoma
Epstein-Barr Virus Status in Diffuse Large B Cell Lymphoma
The investigators analyzed clinical outcome in DLBCL patients according to age group to define the impact of EBV status on the clinical outcome.
- Trial name
- NCT02060435
- Testing
- EBER
- Where
- South Korea
- Volunteers
- 571 people
- Sponsor
- Samsung Medical Center
Myelodysplastic Syndrome
Platelet Response During the Second Cycle of Decitabine Can Predict Response and Survival for Myelodysplastic Syndrome
To assess the efficacy of decitabine and identify predictors for response to decitabine therapy.
- Trial name
- NCT02045654
- Where
- South Korea
- Volunteers
- 1 people
- Sponsor
- Samsung Medical Center
Panic Disorder
A Long-term Observational Study on the Efficacy of SSRIs or Combined Treatment(SSRIs+ CBT) in Panic Disorder Patients
It is known that the treatment of panic disorder with medication and psychotherapy are both effective. Representative as a treatment for panic disorder, Selective serotonin reuptake inhibitors (SSRIs) are recommended as…
- Trial name
- NCT01674673
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Samsung Medical Center