Clinical trials: sponsored by Samsung Medical Center
Small Cell Lung Cancer
Early Versus Late Concurrent Chemoradiation for Limited Stage Small-cell Lung Cancer
The purpose of the study is to evaluate the efficacy and toxicity of different timing of concurrent chemoradiation in the treatment of limited disease status Small-cell lung cancer.
- Trial name
- NCT01125995
- Testing
- early CCRT, late CCRT
- Where
- 2 sites in South Korea
- Volunteers
- 222 people
- Sponsor
- Samsung Medical Center
Squamous NSCLC
Phase II Study of Dovitinib for FGFR1 Amplified Squamous Non-small Cell Lung Cancer
Efficacy of Dovitinib for Squamous NSCLC.
- Trial name
- NCT01861197
- Testing
- Dovitinib
- Where
- South Korea
- Volunteers
- 27 people
- Sponsor
- Samsung Medical Center
Shoulder Arthroscopic Surgery
The Effect of the Shoulder Arthroscopic Surgery on Respiratory Mechanics
During shoulder arthroscopic surgery, extravasation of irrigation fluid can occur around the shoulder and trachea, compressing the upper airway.
- Trial name
- NCT01407328
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Advanced Gastric Cancer
Sunitinib + Docetaxel as Second-line Treatment in Gastric Cancer
The purpose of this study is to determine whether Sunitinib and Docetaxel is effective in the treatment of advanced gastric cancer patients who had prior chemotherapy with fluoropyrimidine and platinum.
- Trial name
- NCT01238055
- Testing
- Docetaxel + Sunitinib, Docetaxel only
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Samsung Medical Center
Metastatic Esophageal Squamous Cell Carcinoma
Prognostic Factor Analysis in Metastatic Esophageal Squamous Cell Carcinoma
Esophageal squamous cell carcinoma is considerably more prevalent in East Asia. Despite of relatively high prevalence of esophageal SCC, prognosis is very poor with limited options of effective chemotherapy regimens.
- Trial name
- NCT01472419
- Volunteers
- 239 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease
Optimal Strategy for Side Branch Stenting in Coronary Bifurcation Lesion
The purpose of this study is to establish the optimal strategy for side branch stenting in coronary bifurcation lesion.
- Trial name
- NCT00794014
- Testing
- Conservative strategy, Aggressive strategy
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Samsung Medical Center
NK/T Cell Lymphoma
Gemcitabine in NK/T Cell Lymphoma
We retrospectively review patients with refractory or relapsed ENKL who received a gemcitabine-containing regimen
- Trial name
- NCT01660568
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Malignant Lymphoma, P13K-AKT Pathway Deregulation
p-AKT Expression on Clinical Outcomes in Malignant Lymphoma
PI3K(phosphatidylinositol 3-kinase)/AKT pathway is an important oncogenic signaling pathway. However, clinical information about the significance of p-AKT expression in malignant lymphoma is not fully understood yet.
- Trial name
- NCT01789060
- Testing
- p-AKT immunohistochemical staining
- Where
- South Korea
- Volunteers
- 262 people
- Sponsor
- Samsung Medical Center
Ureteral Obstruction
Efficacy and Safety of a Covered Self-expandable Dual-layered Metallic Mesh Stent (UVENTA) in Ureteral Obstruction
The purpose of this study is to evaluate Efficacy and Safety of a covered self-expandable dual-layered metallic mesh stent (UVENTA) in ureteral obstruction.
- Trial name
- UVENTA (NCT01788865)
- Testing
- cSEMS(Covered self-expandable dual-layered metal stent) implant
- Where
- 2 sites in South Korea
- Volunteers
- 92 people
- Sponsor
- Samsung Medical Center
EGFR Mutation Positive Non-small Cell Lung Cancer
Evaluation of EGFR TKI Resistance Mechanism Using Plasma DNA Analysis
To detect resistance gene from serially collected plasma DNA in non-small cell lung cancer harbouring EGFR activating mutation who are being treated with EGFR TKIs by using castPCR method.
- Trial name
- NCT01776684
- Testing
- EGFR TKIs (gefitinib, erlotinib, afatinib, et al)
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Major Depressive Disorder
Comparison of Tianeptine Versus Escitalopram Patients Major Depressive Disorder
The primary object of this study is to confirm the superiority of tianeptine compared to escitalopram on effects that improves subjective and objective cognitive impairments in patients suffering from major depressive disorder.
- Trial name
- CAMPION (NCT01309776)
- Testing
- Tianeptine, Escitalopram
- Where
- 6 sites in South Korea
- Volunteers
- 164 people
- Sponsor
- Samsung Medical Center
Diffuse Large B-cell Lymphoma
Treatment Resistance Related With Gene Expression Profile of Diffuse Large B-cell Lymphoma
The investigators perform a retrospective microarray gene expression profiling study of FFPE from a cohort of DLBCL patients with whole genome cDNA mediated Annealing Selection and Ligation (WG-DASL) assay.
- Trial name
- NCT01606605
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
Ultrasound, Complication
Safety of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration : A Prospective Study
The purpose of this study is to find all kinds of complications and it's frequency related to the Endobronchial Ultrasound- Transbronchial Needle Aspiration (EBUS-TBNA) and to evaluate associated risk factors in patients who…
- Trial name
- NCT01597869
- Testing
- Endobronchial ultrasound
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Samsung Medical Center
Atypical Mycobacteria, Mycobacterium Infections
Rapid Identification of Mycobacteria in Acid-fast Bacilli Smear-positive Respiratory Specimens
The aim of the study is to evaluate the polymerase chain reaction (PCR)-Reverse Blot Hybridization Assay (REBA) for identification of nontuberculous mycobacteria (NTM) species in acid-fast bacilli (AFB) smear-positive respiratory…
- Trial name
- NCT00999076
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease
Statin and Post-interventional Coronary Microcirculation Dysfunction
The purpose of this study is to evaluate the effect of statin on the coronary microcirculation dysfunction measured after percutaneous coronary intervention.
- Trial name
- NCT01751295
- Testing
- Atorvastatin, pre-treatment 80 mg/day for 4 days before PCI
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Samsung Medical Center
Pulmonary Non-tuberculous Mycobacterial Lung Disease
Inhaled Amikacin Treatment for Nontuberculous Mycobacterial Lung Disease
The incidence of chronic pulmonary disease caused by nontuberculous mycobacteria (NTM) in human immunodeficiency virus (HIV)-negative patients has been increasing worldwide.
- Trial name
- NCT01528930
- Testing
- Amikacin
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Carcinoma, Non-Small Cell Lung
Endobronchial Ultrasound- Transbronchial Needle Aspiration (EBUS-TBNA) Versus Mediastinoscopy for Mediastinal Lymph Node Staging of Non-small Cell Lung Cancer (NSCLC)
Accurate staging of the mediastinum is essential to evaluate prognosis in non-small cell lung cancer and to devise an appropriate treatment plan.
- Trial name
- NCT01079520
- Testing
- Endobronchial ultrasound (EBUS), Mediastinoscopy
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Samsung Medical Center
Myocardial Reperfusion, Myocardial Infarction
Effects of Postconditioning On Myocardial Reperfusion
The purpose of this study is to investigate the effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction.
- Trial name
- POST (NCT00942500)
- Testing
- Post-conditioning
- Where
- South Korea
- Volunteers
- 700 people
- Sponsor
- Samsung Medical Center
Sepsis, Liver Failure
Lactate Clearance According to the Presence of Hepatic Dysfunction
The purpose of this study is to compare lactate clearance in patients with severe sepsis and septic shock according to the presence of hepatic dysfunction.
- Trial name
- NCT01709565
- Where
- South Korea
- Volunteers
- 245 people
- Sponsor
- Samsung Medical Center
Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome in Korean Patients Taking α1-Adrenergic Receptor Antagonists
Intraoperative floppy iris syndrome (IFIS) is a recently described condition observed during cataract surgery. It has been hypothesized that irreversible atrophy of the iris dilator muscle associated with α1-adrenergic receptor…
- Trial name
- NCT01704014
- Volunteers
- 150 people
- Sponsor
- Samsung Medical Center