Clinical trials: sponsored by Samsung Medical Center
Chemotherapy-Induced Nausea and Vomiting, Ovarian Cancer
Safety and Efficacy of Aprepitant, Ramosetron, and Dexamethasone for Chemotherapy-Induced Nausea and Vomiting in Patients With Ovarian Cancer Treated With Taxane/Carboplatin
The current recommended guideline for patients receiving moderately emetogenic chemotherapy (MEC) is the combination of a 5-HT3 receptor antagonist and corticosteroid.
- Trial name
- NCT01012336
- Testing
- Aprepitant/Ramosetron/Dexamethasone
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Samsung Medical Center
Uterine Myoma, Ovarian Cyst
The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing Gynecologic Laparoscopic Surgery With Trendelenburg Position
In patients undergoing gynecologic laparoscopic surgery with trendelenburg position, the disturbance of pulmonary gas exchange frequently occurs due to high intra-abdominal pressure.
- Conditions
- Uterine Myoma, Ovarian Cyst, Laparoscopic Gynecologic Surgery
- Trial name
- NCT01379313
- Testing
- conventional I:E ratio, 1:1 ratio, 2:1 group
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Alzheimer's Disease
Clinical Research Center for Dementia of South Korea (CREDOS)(or CRCD)
The objective of this study is to present evidence-based medicine for development of clinical practice guideline through prospective study of Alzheimer's disease(AD) and mild cognitive impairment(MCI) in korea
- Trial name
- CREDOS (NCT01198093)
- Where
- South Korea
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Diffuse Large B-cell Lymphoma (DLBCL)
Intensified 1st Cycle Rituximab Plus 8th Cycles of R-CHOP Chemotherapy in Patients With Advanced or Bulky CD20+ Diffuse Large B-cell Lymphoma (DLBCL)
The purpose of this study is to evaluate the complete response (CR) rate after Intensified 1st cycle Rituximab plus 3rd cycles of R-CHOP in DLBCL
- Trial name
- NCT01054781
- Testing
- Rituximab
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- Samsung Medical Center
Crohn's Disease
Expression of TIM-3 and Correlation With Disease Activity in Pediatric Crohn's Disease With Anti TNF-α Therapy
This study investigated the expression of T-cell immunoglobulin- and mucin-domain-containing molecule 3 (TIM-3) in the colonic mucosa and/or the peripheral blood of children with Crohn's disease during anti TNF-α (infliximab)…
- Trial name
- NCT01661257
- Testing
- Infliximab
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Extranodal NK/T Cell Lymphoma
Retrospective Analysis of Skin/Soft Tissue Primary NK/T Cell Lymphoma
To study clinical features, prognostic factors and treatment outcome and to develop a possible prognostic index in skin/soft tissue primary NK/T cell lymphoma patients.
- Trial name
- NCT01341119
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Coronary Bifurcation Lesion
Coronary Bifurcation Stenting (COBIS) Registry in South Korea
The COBIS registry is multi-center, real-world registry of drug-eluting stenting in coronary bifurcation lesions in South Korea.
- Trial name
- COBIS (NCT00851526)
- Where
- South Korea
- Volunteers
- 1,919 people
- Sponsor
- Samsung Medical Center
Prader-Willi Syndrome, Obesity
Plasma Adiponectin Level and Sleep Structures in Children With Prader-Willi Syndrome
Context: Adiponectin is an adipose tissue-derived hormone with an insulin sensitizing effect, and has been related to obstructive sleep apnea syndrome.
- Trial name
- NCT01622751
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Acute Respiratory Distress Syndrome
Predictors for Responsiveness to Corticosteroid in Patients With Early Acute Respiratory Distress Syndrome
In a recent multicenter randomized controlled trial, prolonged administration of low-dose methylprednisolone (1mg/kg/day) initiated in early acute respiratory distress syndrome was associated with earlier resolution of pulmonary…
- Trial name
- NCT01093287
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Thyroid Cancer
Efficacy of Subfascial Approach in Thyroidectomy to Quality of Life in Thyroid Disease Patients
Subfascial approach method in thyroidectomy maybe result in better quality of life than conventional approach method in thyroid disease patients
- Trial name
- NCT01616316
- Testing
- subfascial flap, subplatysmal flap
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
CNS Lymphoma
High-Dose (HD) Methotrexate (MTX) Induction Chemotherapy Followed by Alternative HD MTX-based and HD Cytarabine-based Combination Consolidation Chemotherapy for Newly Diagnosed Primary CNS Lymphoma; CISL 10-01 Study
The purpose of this study is to evaluate the complete response (CR) rate after HD-MTX induction chemotherapy followed by alternative HD MTX-based and HD Cytarabine-based combination consolidation chemotherapy
- Trial name
- NCT01083342
- Testing
- MTX, MVD, VIA
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Patients Treated With Alemtuzumab
Infections Associated With the Use of Alemtuzumab
The aim of this study is to propose infection prophylaxis from Asian multinational retrospective analysis of infectious complications in patients who were treated with alemtuzumab
- Trial name
- NCT01315457
- Where
- 5 sites in China, Indonesia and 3 more
- Volunteers
- 182 people
- Sponsor
- Samsung Medical Center
Lymphoma
Samsung Medical Center-Lymphoma Cohort Study
The purpose of this study is to establish a model which can predict the treatment outcome and the risk of treatment-related morbidity in patients with lymphoma.
- Trial name
- SMC-LCS (NCT00822731)
- Testing
- Chemotherapy with or without radiotherapy
- Where
- South Korea
- Volunteers
- 953 people
- Sponsor
- Samsung Medical Center
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Retrospective Review a Comprehensive Case Database of HoLEP Procedure Performed by a Single Surgeon
Persistent detrusor overactivity (DO) after transurethral prostatectomy results in symptomatic failure in more than one third of the patients.
- Trial name
- NCT01604148
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Samsung Medical Center
Brain Surgery With Motor Evoked Potential Monitoring, Spine Surgery With Motor Evoked Potential Monitoring
Strategy for Maintaining Partial Neuromuscular Blocking Adequate for Motor Evoked Potential During Neurosurgery
The maintenance of partial neuromuscular blocking during general anesthesia for neurosurgery is essential for intraoperative motor-evoked potential monitoring.
- Trial name
- NCT01388868
- Testing
- TOF count guided adjustment, T1/ T0 guided adjustment, T2/ T0 guided adjustment
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Age-Related Cognitive Decline
The Efficacy of Robot Assisted Group Cognitive Training in Elderly Adults Without Cognitive Impairment
Previous studies about cognitive intervention targeting older adults revealed that cognitive training had effects on the improvement of cognitive function.However, researches are rare that investigated direct changes of brain…
- Trial name
- NCT01596205
- Testing
- Robot assisted cognitive training, Conventional cognitive training group
- Where
- South Korea
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Rhegmatogenous Retinal Detachment
Topographic Changes of Retinal Layers After Resolution of Acute Retinal Detachment
Experimental retinal detachment and reattachment models have demonstrated the recovery process of successfully reattached retina.
- Trial name
- NCT01587794
- Volunteers
- 21 people
- Sponsor
- Samsung Medical Center
Internal Jugular Vein Cannulation, Common Carotid Artery
Effect of Shoulder Traction on Size and Relative Position of Internal Jugular Vein to Carotid Artery
Internal jugular vein (IJV) catheterization is frequently performed in infants undergoing major surgery. Although it has been suggested that head rotation increases the degree of overlapping between IJV and carotid artery (CA)…
- Conditions
- Internal Jugular Vein Cannulation, Common Carotid Artery, Infants
- Trial name
- NCT01575184
- Testing
- caudo-ipsilateral traction of shoulder, The ultrasonographic measurements without shoulder traction
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Samsung Medical Center
Graft-Versus-Host Disease, GVHD
Umbilical Cord Blood-derived Mesenchymal Stem Cells for the Treatment of Steroid-refractory Acute or Chronic Graft-versus-host-disease
Graft-versus-host-disease (GVHD) is a major complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT) which may cause acute life-threatening morbidity or chronic disabilities.
- Conditions
- Graft-Versus-Host Disease, GVHD, Allogeneic Hematopoietic Transplant, Disorder Related to Transplantation
- Trial name
- GVHD-MSC (NCT01549665)
- Testing
- Human umbilical cord blood-derived mesenchymal stem cells
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Crohn's Disease
The Effect of a Probiotic Preparation (VSL#3) Plus Infliximab in Children With Crohn's Disease
The purpose was to evaluate as to whether administration of infliximab of 12 week interval with supplementary VSL#3 is more effective or at least of similar efficacy when compared to conventional administration of infliximab only…
- Trial name
- NCT01548014
- Testing
- VSL#3
- Where
- South Korea
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center