Clinical trials: sponsored by Samsung Medical Center
WHYX Lesion, Extremely Well Differentiated Intestinal-type Adenocarcinoma
Clinical Outcomes of Endoscopic Resection for Treating WHYX Lesion
Endoscopically, WHYX cancers demonstrated a vague extent of tumor spread due to pale color changes in both the background atrophic and metaplastic gastric mucosa.
- Trial name
- NCT01451034
- Testing
- WHYX cancer group
- Where
- South Korea
- Volunteers
- 872 people
- Sponsor
- Samsung Medical Center
Cancer
Comparison of Harmonic Scalpel to Conventional Diathermy in Perforator Flap Elevation for Head and Neck Reconstruction
This study is to compare the efficacy of Harmonic Scalpel with conventional diathermy technique in terms of reducing elevation time and perioperative complications of perforator flaps for head and neck reconstruction.
- Trial name
- NCT01092468
- Testing
- Diathermy, Harmonic Scalpel
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Pancreatic Mass, Peripancreatic Mass
Endoscopic Ultrasound-guided Fine Needle Aspiration of Solid Masses: Histological and Immunohistochemical Evaluation
The aim of this retrospective single center study was to evaluate the clinical utility of histological and immunohistochemical analyses of specimens obtained by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA).
- Trial name
- NCT01437410
- Testing
- EUS-FNA
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Samsung Medical Center
Cerebral Infarction
Identification the Cause of Silent Cerebral infarctiON in Healthy Subjects (ICONS)
We hypothesized that paradoxical embolism may be one of the main mechanisms of silent cerebral infarction (SCI) located outside the perforating artery territory.
- Trial name
- ICONS (NCT01429948)
- Where
- South Korea
- Volunteers
- 581 people
- Sponsor
- Samsung Medical Center
Type 2 Diabetes Mellitus
Pharmacodynamics of Mitiglinide/Sitagliptin Compared to Mitiglinide and Sitagliptin
1. Explore pharmacodynamics glucose insulin C-peptide glucagon intact GLP-1 DPP-4 activity CGMS (continuous glucose monitoring system) 2. Assess Safety adverse events clinical laboratory test physical examination
- Trial name
- NCT01422590
- Testing
- Sitagliptin, Mitiglinide, Sitagliptin, Mitiglinide
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease
The Optimal Duration of Dual Antiplatelet Therapy After Implantation of Endeavor Stent
The purpose of this study to determine whether the dual antiplatelet therapy (aspirin and clopidogrel) for 3 months after coronary implantation of zotarolimus-eluting stent is safe in terms of death, myocardial infarction, or…
- Trial name
- DATE (NCT00418860)
- Testing
- Aspirin, Clopidogrel
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Samsung Medical Center
Preterm Premature Rupture of the Membranes
Antibiotics Study in Preterm Premature Rupture of the Membranes
The purpose of this study is to compare the efficacy on maternal infection, chorioamnionitis and neonatal morbidity and mortality, and to review the evidence and provide recommendations on the use of antibiotics in PPROM.
- Trial name
- PPROM (NCT01401179)
- Testing
- cefazolin, erythromycin, clarithromycin
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Samsung Medical Center
Benign Prostatic Hyperplasia
Effects of Tamsulosin 0.4mg on Clinical Outcomes in Korean Men With Severe Symptomatic Benign Prostatic Hyperplasia (BPH)
The purpose of this study is to compare the efficacy and safety of tamsulosin 0.4mg (Harnal® D. 0.2mg, 2T) with tamsulosin 0.2mg (Harnal® D 0.2mg, 1T) in patients with severe symptomatic benign prostatic hyperplasia as a first…
- Trial name
- NCT01404637
- Testing
- Tamsulosin 0.4mg, Tamsulosin 0.2mg
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Prader Willi Syndrome, Obesity
Characterization of Transcriptional Regulators of Ghrelin Hormone Which Causes Genetic Obesity
The problem point of the Prader-Willi Syndrome (PWS) patient is the obesity which is intense and the plasma ghrelin level which increases unusual from the recently PWS patients was discovered.
- Trial name
- NCT01404624
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Cardiac Arrest
The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild Hypothermia
Cardiac arrest is a leading cause of sudden death, but the survival rate of cardiac arrest is only 5-35%. Although, the first resuscitation of cardiac arrest patient would be success, the hypoxic brain injury after cardiac arrest…
- Trial name
- NCT01083784
- Testing
- Use of prophylactic anticonvulsants (valproate, clonazepam), Control group
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Schizophrenia, Schizoaffective Disorder
Effects of Atypical Antipsychotics on Appetite and Eating Behavior of Schizophrenia Patients
In this study, we are going to investigate quantitative and qualitative natures of appetite and eating-behavior changes induced by atypical antipsychotics, i.e., risperidone, olanzapine and aripiprazole, in schizophrenia patients.
- Trial name
- NCT01043250
- Where
- South Korea
- Volunteers
- 81 people
- Sponsor
- Samsung Medical Center
Panic Disorder
Changes of Cerebral Glucose Metabolism After 12 Weeks of Paroxetine Treatment in Panic Disorder
Panic disorder is one of the most prevalent and disabling psychiatric disorders. Brain regions such as amygdala, hippocampus, periaqueductal gray (PAG), locus coeruleus, parahippocampal gyrus, frontal cortex, and thalamus has…
- Trial name
- NCT00767754
- Testing
- Paxil CR
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Pain
Efficacy of rTMS (Repetitive Transcranial Magnetic Stimulation) on Patients With Somatoform Pain Disorder
Chronic somatoform pain is common in psychiatric patients. Chronic somatoform pain causes significant distress and disrupts social functioning. Moreover, chronic somatoform pain often does not sufficiently respond to medication.
- Trial name
- NCT00726791
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Samsung Medical Center
Non-small Cell Lung Cancer
Pemetrexed/Cisplatin Versus Gemcitabine/Cisplatin According to Thymidylate Synthase Expression
This study trys to evaluate the predictive role of thymidylate synthase expression for pemetrexed/cisplatin in Non-small Cell Lung Cancer (NSCLC).
- Trial name
- NCT01401192
- Testing
- Gemcitabine plus cisplatin, pemetrexed plus cisplatin
- Where
- South Korea
- Volunteers
- 304 people
- Sponsor
- Samsung Medical Center
Panic Disorder
Changes of Cerebral Glucose Metabolism and After 12 Weeks of Escitalpram Treatment in Panic Disorder
Panic disorder is one of the most prevalent psychiatric disorders and recently abnormal fear network is known to be implicated in the pathophysiology of panic disorder.
- Trial name
- NCT00767871
- Testing
- Lexapro
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Atrial Fibrillation
Biochemical Marker to Predict the Recurrence of Atrial Fibrillation After Surgical Maze Procedure
The role of plasma NT-proBNP, hsCRP, TIMP-1(Tissue inhibitors of MetalloProteinase-1),TGF-b, MMP-3(Matrix MetalloProteinase-3), and pro-MMP-1 in predicting the recurrence of AF after surgical Maze procedure.
- Trial name
- NCT00542659
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center
Inflammatory Lung Diseases, Hemoptysis
The Expression of Serum Angiogenesis Marker in Patients Presenting With Hemoptysis
Vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2) are major mediators of angiogenesis and are induced by tissue inflammation and hypoxia.
- Trial name
- NCT01171768
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Samsung Medical Center
Unilatral Pleural Effusion
Diagnostic Utility of Pleural Fluid MAGE Assay in Patients With Pleural Effusion From Primary Lung Cancer
Melanoma antigen (MAGE) gene is known to be expressed in tumor cells, testis and placenta. The purpose of this prospective study was to investigate the sensitivity, specificity and accuracy of pleural fluid MAGE gene expression…
- Trial name
- NCT01179685
- Testing
- pleural fluid tapping
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Uterine Myoma, Uterine Adenomyosis
Study of Different Pain Scores in Single-Port Access (SPA) Laparoscopic Hysterectomy Versus Conventional Laparoscopic Hysterectomy
Purpose: The attempt to further reduce the operative trauma in laparoscopic hysterectomy led in new technique such as Single-Port Access (SPA) laparoscopic surgery.
- Trial name
- NCT01064128
- Testing
- conventional laparoscopic hysterectomy, SPA laparoscopic hysterectomy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Acromioclavicular Joint Arthritis
Distal Clavicle Resection With Rotator Cuff Repair
The purpose of this study is to determine whether distal clavicle resection is effective treatments in patients with acromioclavicular joint pain accompanied by rotator cuff tear.
- Trial name
- NCT01040065
- Testing
- distal clavicle resection
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center