Clinical trials: sponsored by Samsung Medical Center
Deviated Nasal Septum
Perioperative Administration of Pregabalin for Pain After Septoplasty
Pregabalin is used for the treatment of neuropathic pain and has shown analgesic efficacy in postoperative pain. The aim of this randomized, double-blinded, placebo-controlled trial was to investigate the efficacy and safety of…
- Trial name
- NCT01370915
- Testing
- Pregabalin (Lyrica)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Patients With Acute Myeloid Leukemia, Patients Receiving Induction/Consolidation Chemotherapy
Genetic Predictive Model Based on Single Nucleotide Polymorphisms in the DNA Repair Pathway and Drug Metabolis/Transport Pharmacogenetics in the Prediction of Response and Treatment Outcomes in Acute Myeloid Leukemia
The main component in the treatment of acute myeloid leukemia (AML) is consist of anthracycline (such as daunorubicin or idarubicin) and cytarabine.
- Trial name
- NCT01106144
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Rotator Cuff Tear
Duration of Immobilization After Rotator Cuff Repair: Its Clinical Impact
The purpose of this study is to determine whether the immobilization period is helpful for the better healing of repaired rotator cuff.
- Trial name
- NCT00891566
- Testing
- Immobilization
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Pancreatic Neoplasm, Neoplasm of Intra-abdominal Lymph Nodes
Prospective Study Comparing Methods of Obtainment of Specimen After EUS-FNA in Patients With Peri-pancreatic Mass
EUS-guided FNA has been proved to be a safe and useful method for tissue sampling of gastrointestinal track lesions and other organ lesions including mediastinal and intra-abdominal lymph nodes, pancreas and hepatobiliary tree.
- Trial name
- EUS-FNA (NCT01354795)
- Testing
- 1.EUS-FNA with or without suction, 2.Pushing the stylet or injecting air
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Samsung Medical Center
Chronic Prostatitis, Chronic Pelvic Pain Syndrome
Efficacy of Electromagnetic Stimulation Therapy for Chronic Prostatitis and Chronic Pelvic Pain Syndrome
In 1995 the National Institutes of Health-National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) workshop reached a consensus on the definition and classification of prostatitis syndromes.The commonest and yet…
- Trial name
- NCT00922012
- Testing
- Electromagnetic Stimulation Therapy
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Kidney Transplantation, Living Donors
Randomized Trial of Cyclosporine and Tacrolimus Therapy With Steroid Withdrawal in Living-Donor Renal Transplantation
The use of steroids after kidney transplantation has been challenged because of variable adverse effects which may increase the patient morbidity and mortality.
- Trial name
- NCT00777933
- Testing
- tacrolimus, cyclosporine
- Where
- South Korea
- Volunteers
- 131 people
- Sponsor
- Samsung Medical Center
Rotator Cuff Tear
Single Versus Double Row Suture Anchor Repair in Medium to Large Rotator Cuff Tears
The purpose of this study is to determine whether double row repair is better in healing than traditional single row repair in arthroscopic rotator cuff repair.
- Trial name
- NCT01039571
- Testing
- double row repair
- Where
- South Korea
- Volunteers
- 71 people
- Sponsor
- Samsung Medical Center
Nonsmall Cell Lung Cancer
Iressa for EGFR Mutation Negative Non-small Cell Lung Cancer (NSCLC)
The investigators will examine efficacy and toxicity of gefitinib in Korean patients with EGFR wild tumors diagnosed with direct sequence test.
- Trial name
- NCT01312337
- Testing
- salvage iressa
- Where
- 2 sites in South Korea
- Volunteers
- 92 people
- Sponsor
- Samsung Medical Center
Nasopharyngeal Cancer
Weekly Docetaxel Plus Cisplatin as the First-line Therapy for Nasopharyngeal Cancer
The investigators will evaluate weekly docetaxel plus 3-weekly cisplatin regimen as the first-line therapy for recurrent of metastatic nasophayngeal cancer
- Trial name
- NCT01312311
- Testing
- Docetaxel, Cisplatin
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Samsung Medical Center
Delayed Bleeding,, Healing Ulcer
Efficacy of Ecabet Sodium and Proton Pump Inhibitor Combination Therapy in the Treatment of Iatrogenic Ulcer After Endoscopic Submucosal Dissection
Endoscopic submucosal dissection (ESD) is widely indicated to treat gastric adenomas and early gastric cancer (EGC).ESD is able to obtain en bloc resection of larger specimens.
- Conditions
- Delayed Bleeding,, Healing Ulcer, Quality of Ulcer
- Trial name
- NCT01308177
- Testing
- Ecabet
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Angioplasty, Transluminal, Percutaneous Coronary
Effect of Atorvastatin Administration Before Primary Percutaneous Coronary Intervention
The purpose of this study to determine whether statin pretreatment decrease myocardial infarct size in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention.
- Trial name
- NCT00610870
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 173 people
- Sponsor
- Samsung Medical Center
Nonsmall Cell Lung Cancer
Chemotherapy With or Without Radiosurgery for Asymptomatic Oligo Brain Metastasis
The need of radiosurgery is controversial for asymptomatic oligo brain metastasis for non small cell lung cancer (NSCLC). Therefore, the investigators do a randomized study comparing overall survival between two groups with or…
- Trial name
- NCT01301560
- Testing
- Radiosurgery, Observation
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Samsung Medical Center
Graft vs Host Disease
Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patients
Antifungal prophylaxis should be used in patients being treated with glucocorticoids for graft-versus-host disease (GVHD) following allogeneic hematopoietic stem-cell transplantation (HSCT).
- Trial name
- ITRAG (NCT01282879)
- Testing
- Itraconazole
- Where
- 9 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Stomach Cancer, Gastrectomy
The Use of Ultrasonic Coagulating Shears Compared to Monopolar Electrocautery in Open Gastric Cancer Surgery
Ultrasonic coagulating shears are made for performing for cutting and hemostasis at once during operation. It was proved that a laparoscopic gastric resection showed significantly shorter operative time and less work load…
- Conditions
- Stomach Cancer, Gastrectomy, Ultrasonic Coagulating Shears
- Trial name
- NCT01179750
- Testing
- Ultrasonic Coagulating Shears
- Where
- South Korea
- Volunteers
- 256 people
- Sponsor
- Samsung Medical Center
Hypertrophic Cicatrix
An Investigator-blind Multi-center Prospective Study for the Efficacy and Safety of Silicon Gel (Dermatix)
Silicone gel is a self-drying silicone polymer that forms thin film after application onto the skin. Because silicone film is a medical device, silicone gel is also regarded as a medical device.
- Trial name
- NCT01004536
- Testing
- silicone gel, no treatment
- Where
- 3 sites in South Korea
- Volunteers
- 47 people
- Sponsor
- Samsung Medical Center
Hemoglobinuria, Paroxysmal
Multicenter Retrospective Analysis About the Clinical Characteristics of Korean Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients
Paroxysmal nocturnal hemoglobinuria (PNH) is a hematopoietic stem cell disorder in which unregulated activation of the complement system leads to significant ischemic morbidities with shortened lifespan.
- Trial name
- NCT01224483
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
Diabetic Retinopathy, Macular Edema
Triple Therapy of Pars Plana Vitrectomy and Grid/Focal Laser for Diabetic Macular Edema (DME)
This study is designed to report 3-year result of triple therapy of vitrectomy, intravitreal triamcinolone and macular laser photocoagulation for intractable diabetic macular edema.
- Trial name
- NCT01202461
- Testing
- Triple therapy of vitrectomy, IVTA and grid/focal laser photocoagulation
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Samsung Medical Center
Carcinoma, Non-Small-Cell Lung
Efficacy Study of Induction Chemotherapy Before Surgery in Operable Non-small Cell Lung Cancer
This study is randomized phase III trial designed to assess whether (preoperative) neoadjuvant chemotherapy followed by surgery plus adjuvant chemotherapy with gemcitabine and cisplatin (experimental treatment) improves 3-year…
- Trial name
- NCT00329472
- Testing
- gemcitabine, cisplatin
- Sponsor
- Samsung Medical Center
Overactive Bladder
Efficacy and Safety of Selective Serotonin Reuptake Inhibitor (SSRI) in Overactive Bladder Patients
The urologic literature suggests that there is an association between a variety of psychiatric disorders and incontinence. Most notably, depression is found in a significant percentage of patients with urinary incontinence.
- Trial name
- NCT00902421
- Testing
- Selective serotonin reuptake inhibitors, Antimuscarinics
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Benign Prostatic Hyperplasia
Effects of Chronic Use of Doxazosin in Men With Benign Prostatic Hyperplasia
In this study, we investigate the changes of the expression of alpha adrenergic receptor in the prostate tissue during 2-yr medication period in the man with benign prostatic hyperplasia.
- Trial name
- NCT00730418
- Testing
- Doxazosin
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Samsung Medical Center