Clinical trials: sponsored by Seattle Children's Hospital
Cerebral Palsy
Activity and Participation in Ambulatory Cerebral Palsy
The investigators would like to understand how the physical activity levels and body size of a child with cerebral palsy (CP) in a clinical situations versus out in the community relates to what they want to do in day to day life…
- Trial name
- APCP (NCT01217242)
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Seattle Children's Hospital
Diabetes Mellitus, Type I
The Effectiveness of Continuous Glucose Monitoring in Diabetes Treatment for Infants and Young Children
The purpose of this study is to see if the use of a real-time glucose sensor improves diabetes control in young children (less than 4 years old) with Type I diabetes when they are initiated on insulin pump therapy.
- Trial name
- Gerber RTSA (NCT00875290)
- Testing
- Real-time glucose sensor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seattle Children's Hospital
Viral Infections
Virus Surveillance in Pediatric Solid Organ Transplant Recipients
Viral infections are an important complication of transplantation. Immunosuppressive therapy interferes with T cell immunity resulting in a high incidence of viral infection.
- Trial name
- NCT00886158
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Seattle Children's Hospital
Asthma
Asthma Learning Project
The purpose of this study is to determine the effect on knowledge and behavior of playing an educational asthma computer game during a pediatric Emergency Department (ED) asthma visit among children ages 7 - 15 years.
- Trial name
- ALP (NCT00874900)
- Testing
- Educational game, Educational game + motivational interview, Motivational interview
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Seattle Children's Hospital
Healthy
Reproducibility of Malaria Challenge in Healthy Volunteers
This is a prospective, single arm, single intervention safety and immunogenicity study in 6 healthy, malaria-naive adults, conducted to demonstrate the successful implementation of the well-established malaria challenge model at…
- Trial name
- NCT01058226
- Testing
- Malaria challenge (wild-type NF54 strain Plasmodium falciparum sporozoites)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Cystic Fibrosis
Study of Yoga as a Therapy for Cystic Fibrosis (CF) Patients
Cystic fibrosis (CF) is a lung disease that affects 30,000 children and adults in the US. Incorporation of regular exercise into the lives of patients with CF is of interest because it may improve lung function and quality of…
- Trial name
- NCT01325766
- Testing
- Yoga
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seattle Children's Hospital
Lumbar Puncture
Pediatric Lumbar Puncture Success Using the COMPASS
Objective: To evaluate pediatric emergency department provider lumbar puncture success with and without the Compass Lumbar Puncture Enhanced, a new pressure transducer, in order to determine: the proportion of lumbar punctures…
- Trial name
- NCT01285531
- Testing
- Compass Lumbar Puncture Enhanced
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Asthma
Airflow Obstruction and Biomarkers of Airway Inflammation During and Following Acute Exacerbations of Childhood Asthma
This study is a longitudinal single-center pilot study designed to describe changes in lung function and levels of noninvasive biomarkers of airway inflammation in children ages 6-18 years over two months following…
- Trial name
- NCT01227070
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Postoperative Pain
Lumbar Plexus Catheter Versus Femoral Nerve Catheter for Postoperative Pain After Anterior Cruciate Ligament (ACL) Repair
Randomized trial comparing lumbar plexus catheter versus femoral nerve catheter (single-shot femoral block as control group) for postoperative pain control after anterior cruciate ligament repair in children (age 11-21).
- Trial name
- NCT01068275
- Testing
- lumbar plexus catheter, femoral nerve catheter, single-shot femoral block
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Seattle Children's Hospital
Inflammatory Bowel Disease, Ulcerative Colitis
Curcumin in Pediatric Inflammatory Bowel Disease
This is a single center, open label forced dose titration study designed to determine the tolerability of curcumin in pediatric patients with inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease
- Trial name
- NCT00889161
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Seattle Children's Hospital
Depression
Behavioral Activation With Depressed Adolescents
Twenty percent of adolescents will have at least one episode of clinical depression by age 18, and 65% will experience transient or less severe depressive symptoms.
- Trial name
- NCT01137149
- Testing
- Behavioral Activation Therapy, Treatment as Usual- Psychotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Neoplasms, Benign, Neoplasms, Malignant
Radiofrequency Ablation (RFA) Of Tumors Acquired In Childhood
This is a single-center, Phase II study including only patients on whom a decision to conduct radiofrequency ablation (RFA) has already been made.
- Trial name
- NCT00868647
- Testing
- Radiofrequency ablation (RFA)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Cystic Fibrosis
Antimicrobial Resistance in Cystic Fibrosis (CF)
People with cystic fibrosis (CF) often develop chronic pulmonary infections which are caused by a variety of organisms, the most predominant being Pseudomonas aeruginosa. Antibiotics are important in managing CF lung infections.
- Trial name
- NCT00360503
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Seattle Children's Hospital
Inactivated Influenza Vaccine
Safety and Immunogenicity of Inactivated Influenza Virus Vaccine Among Healthy Children 6-12 Weeks of Age
Study of the safety and immunogenicity (antibody producing capability) comparing inactivated influenza vaccine to placebo given to infants at 2 and 3 months of age.
- Trial name
- GRC28 (NCT00242424)
- Testing
- 2005-2006 trivalent inactivated influenza vaccine
- Where
- United States
- Volunteers
- 1,375 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Cystic Fibrosis, Chronic Bronchitis
Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)
This was a randomized multi-center clinical trial to compare the microbiological efficacy, clinical efficacy, and safety of using standard versus biofilm susceptibility testing of P.
- Trial name
- NCT00153634
- Testing
- IV amikacin, PO azithromycin, IV ceftazidime
- Where
- 8 sites in United States
- Volunteers
- 75 people
- Sponsor
- Seattle Children's Hospital