Clinical trials: sponsored by Seattle Children's Hospital
Recurrent Childhood Brain Tumor
Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors
This research study is a Feasibility clinical trial. In this trial, researchers are trying to figure out whether a medication can be chosen based on rapid testing done on tumor tissue.
- Trial name
- SEED (NCT02015728)
- Testing
- Tumor biology testing, Temozolomide, Etoposide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seattle Children's Hospital
Physical Activity, Quality of Life
mHealth Intervention to Promote Cancer Survivors' Physical Activity
The Primary Goal is to conduct a 5-10 week randomized controlled trial (RCT) of the Fitbit Flex, a popular, affordable, wearable physical activity tracking device, and the Fitbit mHealth app.
- Trial name
- NCT02469727
- Testing
- Fitbit, Facebook group
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia
Seattle-PAP Bubble Nasal CPAP and Work of Breathing
The investigators propose to test the hypothesis that Seattle bubble nasal continuous positive airway pressure (Seattle-PAP) supports respiratory physiology in very low birth weight (VLBW) infants more effectively than standard…
- Conditions
- Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia, Newborn Primary Sleep Apnea
- Trial name
- Seattle-PAP (NCT02210026)
- Testing
- Seattle-PAP
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seattle Children's Hospital
Physical Activity
A Wearable mHealth Device to Promote Teenagers' Physical Activity
Due to disparities in childhood obesity, interventions for physical activity promotion and obesity prevention for low socioeconomic and racial/ethnic minority children and adolescents are vital to address disparities across the…
- Trial name
- NCT02031185
- Testing
- FitBit only, FitBit and Text Messages
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Physical Activity
Pilot and Feasibility Bicycle Train Study
US children's active commuting to school (ACS; walking or cycling to school), previously common (48% in 1969) is now uncommon (13% in 2009).
- Trial name
- NCT02006186
- Testing
- Bicycle Train
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Pediatric Presentation of Urinary Tract Infection
Lidocaine Analgesia for Urethral Catheterization in Children
Primary Aim 1. To measure difference in pain via Faces, Legs, Activity, Cry and Consolability (FLACC) Pain Scale score at the time of transurethral bladder catheterization for urine collection in children who do and do not…
- Trial name
- NCT01780324
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Seattle Children's Hospital
Legg-Calve Perthes Disease
Intraarticular Corticosteroid Therapy in Perthes Disease.
Legg-Calve-Perthes disease (LCP) represents the loss of blood flow to the head of the femur, resulting in significant hip pain and potential long term disability.
- Trial name
- NCT01026909
- Testing
- Aristospan 20mg
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Seattle Children's Hospital
Malaria
Safety, Attenuation and Immunogenicity of GAP3KO Administered Via A Stephensi Mosquitoes
Study designed to evaluate safety and tolerability of a genetically attenuated P. falciparum (GAP3KO) that arrests early in the liver stage of the parasite life cycle.
- Trial name
- NCT02313376
- Testing
- GAP3KO
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Intestinal Failure, Rotavirus Vaccines
Pilot Study of the Rotavirus Vaccine in Infants With Intestinal Failure
The purpose of this study is to assess the safety and immune response of the rotavirus vaccine in infants who have undergone abdominal surgery.
- Trial name
- NCT00995813
- Testing
- Rotarix
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Seattle Children's Hospital
Cystic Fibrosis, Growth Failure
Baby Observational and Nutritional Study
Cystic fibrosis (CF) is a life-shortening disease that causes breathing and digestive problems, but can now be diagnosed at the time of birth. Lung function is very hard to measure in infants, but growth is not.
- Conditions
- Cystic Fibrosis, Growth Failure, Exocrine Pancreatic Insufficiency
- Trial name
- BONUS (NCT01424696)
- Where
- 28 sites in United States
- Volunteers
- 231 people
- Sponsor
- Seattle Children's Hospital
Craniosynostosis
Child and Infant Learning Project
To learn more about the cognitive and motor development of infants and young children born with a craniofacial defect called craniosynostosis.
- Trial name
- CILP (NCT00077831)
- Testing
- neurobehavioral development
- Where
- 4 sites in United States
- Volunteers
- 535 people
- Sponsor
- Seattle Children's Hospital
Chronic Pain, Headache
Web-based CBT for Children With Chronic Pain
The purpose of this study is to develop and evaluate the feasibility and effectiveness of a web-based (i.e., internet) treatment approach for providing psychological treatment to reduce pain and improve functioning in children…
- Conditions
- Chronic Pain, Headache, Abdominal Pain
- Trial name
- NCT00853138
- Testing
- cognitive-behavioral therapy
- Volunteers
- 48 people
- Sponsor
- Seattle Children's Hospital
Overweight and Obesity
Familial Overweight: Comparing Use of Strategies
The purpose of this study is to compare the efficacy of two different approaches (prescribed \& self-directed) to the treatment of childhood obesity and their relative impact on child weight status, physical activity, and diet.
- Trial name
- FOCUS (NCT00746629)
- Testing
- FOCUS
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Childhood Obesity
Parent Partnership Project
To evaluate the acceptability and feasibility of peers as interventionists in delivering family-based behavioral pediatric weight control intervention.
- Trial name
- NCT01789944
- Testing
- Behavioral: Family-based behavioral intervention
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Seattle Children's Hospital
Asthma
Improving Asthma Outcomes Through Spirometry Distance Learning
Spirometry is a recommended component of asthma diagnosis and treatment in the primary care setting, yet few providers report its routine use for children with asthma.
- Trial name
- NCT01168635
- Testing
- Spirometry 360 program - Virtually-delivered spirometry quality improvement program
- Where
- 4 sites in United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Childhood Obesity
Peer Counseling in Family-Based Treatment for Childhood Obesity
To evaluate the acceptability and feasibility of peers as interventionists in delivering family-based behavioral pediatric weight control intervention.
- Trial name
- EPICH (NCT01789671)
- Testing
- Family-based behavioral intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Seattle Children's Hospital
Limited English Proficient Patients and Families
Comparing Remote Interpreter Modalities in the Pediatric Emergency Department
Professional interpretation improves quality of care for patients with limited English proficiency (LEP). However, many health care settings lack access to professional interpreters, and even in locations with good access…
- Trial name
- NCT01986179
- Testing
- Telephone Interpretation, Video Interpretation
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Seattle Children's Hospital
Infant, Newborn, Diseases, Pain
Study of Morphine in Postoperative Infants to Allow Normal Ventilation
OBJECTIVES: I. Compare nonmechanically ventilated infants who receive morphine postoperatively as intermittent intravenous bolus doses or as a continuous intravenous infusion targeted to reach a steady-state concentration. II.
- Trial name
- NCT00004696
- Testing
- morphine
- Volunteers
- 100 people
- Sponsor
- Seattle Children's Hospital
Pulmonary Hypertension, Neonatal Hypoxic Respiratory Failure
Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients
The purpose of this study is to determine whether inhaled iloprost is safe and effective in pediatric patients with pulmonary hypertension who are sick in the intensive care unit.
- Conditions
- Pulmonary Hypertension, Neonatal Hypoxic Respiratory Failure, Persistent Pulmonary Hypertension of Newborn, Congenital Heart Defects
- Trial name
- NCT00981591
- Testing
- Iloprost
- Sponsor
- Seattle Children's Hospital
Pain
Ultrasound-guided Rectus Sheath Block for Post-operative Pain Control Following Umbilical Hernia Repair
The purpose of this study is to compare the effectiveness of local infiltration to an ultrasound guided nerve block placed by the anesthesiologist for children undergoing umbilical hernia repair.
- Trial name
- NCT00836134
- Testing
- rectus sheath block, local anesthetic infiltration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seattle Children's Hospital