Clinical trials: sponsored by Semmelweis University
Prosthetic Cardiac Valve Thrombosis, Cerebrovascular Accident
Rule Out Transcatheter Aortic Valve Thrombosis With Post Implantation Computed Tomography (RETORIC)
The RETORIC study is a prospective cohort study with a primary aim to assess the incidence and independent predictors of reduced leaflet motion and valve thrombosis after TAVI procedure using multimodality imaging strategy…
- Conditions
- Prosthetic Cardiac Valve Thrombosis, Cerebrovascular Accident, Prosthetic Valve Malfunction
- Trial name
- RETORIC (NCT02826200)
- Testing
- Acenocoumarol, Standard of care
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Dry Eye
A Study of the Effect of Zinc-Hyaluronate on Ocular Surface Sensations in Patients With Dry Eye
Hyaluronic acid, a natural polymer, helps to maintain ocular surface hydration and can already be found in several artificial tears recommended to alleviate symptoms of dry eye.
- Trial name
- NCT02951910
- Testing
- Ophylosa tear supplement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Chronic Central Serous Chorioretinopathy
Eplerenone Treatment for Chronic Central Serous Chorioretinopathy in Hungarian Population
The aim of the study is to determine the efficacy and safety of treatment with the drug eplerenone in patients with chronic central serous chorioretinopathy.
- Trial name
- NCT02462499
- Testing
- Inspra (eplerenone)
- Where
- Hungary
- Volunteers
- 28 people
- Sponsor
- Semmelweis University
Tooth Extraction Status Nos, Edentulous Alveolar Ridge
3D Radiographic Evaluation of a Novel Implant Site Development Technique
The present retrospective study aims at assessing the clinical effects of a novel implant site development (Extraction site development - XSD) technique after tooth extraction compared with extraction alone in patients requiring…
- Trial name
- NCT02660697
- Testing
- Extraction site development
- Where
- Hungary
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Vitamin C Deficiency
"Novo C Plus" Vitamin C Containing Dietary Supplement Bioavailability in Healthy Subjects
The aim of this study is to evaluate the bioavailability of "Novo C Plus" vitamin C containing dietary supplement compared to licensed vitamin C medications. The novelty of this product is the liposomal formulation.
- Trial name
- NCT02606773
- Testing
- Ascorbic Acid
- Where
- Hungary
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Gingival Recession
Post-operative Blood Flow Measurements of the Oral Mucosa
Our overall goal is to characterize the role of the microcirculation in healing oral mucosa after routinely applied surgery intervention in order to facilitate treatment.
- Trial name
- LASCAM (NCT02540590)
- Testing
- laser speckle contrast imaging of the oral mucosa, wound fluid measurement
- Where
- Hungary
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Other Complications Associated With Artificial Fertilization
Comparison of Individual Culture and Group Culture of Preimplantation Embryos in Human IVF Treatments
Prospective randomized comparison of two widely used in vitro culture system in human IVF treatments. In vitro fertilized oocytes and embryos are cultured in individual culture media droplets using conventional petridish or in…
- Trial name
- GroupCulture (NCT01774006)
- Testing
- individual embryo culture or group culture
- Where
- Hungary
- Volunteers
- 532 people
- Sponsor
- Semmelweis University
Glaucoma, Ocular Hypertension
Continuous Intraocular Pressure (IOP) Measurement and Ability to Detect Treatment Effect
Continuous intraocular pressure (IOP) measurement with a contact lens sensor may provide more information on the drug-related IOP change than 24-hour IOP measurement with Goldmann applanation tonometry (GAT.
- Trial name
- NCT01491867
- Testing
- travoprost 0.003%
- Where
- 2 sites in Hungary
- Volunteers
- 9 people
- Sponsor
- Semmelweis University
Retinitis Pigmentosa
Autoimmunity in Retinitis Pigmentosa
Using local immune suppression, the trial seeks evidence for the hypothesis that autoimmunity plays a role in the pathomechanism of retinitis pigmentosa.
- Trial name
- NCT00433277
- Testing
- twice-daily dosage with 0.5% cyclosporine-A eyedrops
- Where
- Hungary
- Sponsor
- Semmelweis University