Clinical trials: sponsored by Shanghai Changzheng Hospital
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Triptolide-Containing Formulation as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Triptolide was shown in experimental studies to inhibit the cyst formation and growth in ADPKD models, while triptolide-containing formulation was revealed to potentially slow the disease progression in several proteinuric ADPKD…
- Trial name
- NCT02115659
- Testing
- Triptolide-Containing Formulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Changzheng Hospital
Cirrhosis
Rifaximin Predicts the Complications of Decompensated Cirrhosis
Cirrhotic patients are predisposed to intestinal dysmotility, bacterial overgrowth, and increased intestinal permeability all leading to an increase in bacterial translocation and increased endotoxemia.
- Trial name
- NCT02074280
- Testing
- rifaximin
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Shanghai Changzheng Hospital
Neoplasms, Chemotherapy-Induced Nausea and Vomiting
Efficacy and Safety of Palonosetron Hydrochloride in the Prevention of Nausea and Vomiting
This purpose of this study is to evaluate the efficacy and safety of single and repeated doses of palonosetron hydrochloride in preventing nausea and vomiting caused by moderate and highly emetogenic chemotherapy in patients.
- Trial name
- ESPNV (NCT01481831)
- Testing
- Palonosetron Hydrochloride
- Where
- 18 sites in China
- Volunteers
- 599 people
- Sponsor
- Shanghai Changzheng Hospital
Small-Bowel Disorders
Single-Operator Versus Dual-Operator Double-balloon Endoscopy in Patients With Small-Bowel Disorders
Double-balloon endoscopy (DBE) is a new device that allows diagnosis and treatment throughout the entire small intestine. Although the originally described method requires two operators, the investigators have recently developed…
- Trial name
- DBE (NCT01184690)
- Testing
- Single-operator double-balloon endoscopy, dual-operator double-balloon endoscopy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Changzheng Hospital
Small-Bowel Disorders
Double- Versus Single-balloon Enteroscopy for Obscure Small-bowel Bleeding
Double-balloon enteroscopy (DBE) is now an established method for diagnostic and therapeutic small-bowel endoscopy. Single-balloon enteroscopy (SBE) has been introduced to simplify the technique.
- Trial name
- DBE;SBE (NCT01176864)
- Testing
- Double-balloon enteroscopy, Single-balloon enteroscopy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Changzheng Hospital
Liver Cirrhosis
A Clinical Trial of the Vessel Sealing System (LigaSure) in Azygoportal Disconnection and Splenectomy in Patients With Portal Hypertension
The aim of this trial was to verify the efficiency of a new surgical device (the LigaSure vessels sealing system) in esophagogastric decongestion and splenectomy in patients with portal hypertension.
- Trial name
- NCT00965744
- Testing
- Vessel sealing system LigaSure
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Changzheng Hospital
Colorectal Disease
The Effect of the Preoperative Oral Carbohydrate Attenuating Immediate Postoperative Insulin Resistance on PI3K Dependent Signaling Pathway
The purpose of this study is to delineate the effects of preoperative oral carbohydrate on immediate postoperative insulin resistance (PIR) in patients undergoing elective open colorectal cancer resection, and to further clarify…
- Trial name
- NCT00755729
- Testing
- Preoperative Oral Carbohydrate
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Shanghai Changzheng Hospital
Hepatitis B Virus, Decompensated Cirrhosis
Entecavir for Patients With Decompensated Hepatitis B Virus (HBV)-Related Cirrhosis
The aim of this study is to evaluate the effect of Entecavir for patients With decompensated HBV-Related cirrhosis.
- Trial name
- NCT00663182
- Testing
- Entecavir
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Changzheng Hospital