Clinical trials: sponsored by Sheba Medical Center
Knee Arthroscopy Skills
Arthroscopy Simulator Training vs OR Training Knee
The purpose of this study is to compare between two groups of residents with basic arthroscopic skills in diagnostic knee arthroscopy.
- Trial name
- ASTOR (NCT02216448)
- Testing
- Training knee simulator, OR Training
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Pterygium
The Corneal and Conjunctiva Sensation Before and After Pterygium Surgeries
The purpose of this current study is to examine the sensation of the corneal and conjunctiva sensation before and after pterygium surgeries by Cochet bonnet esthesiometer and to examine epidemiological, clinical and imaging…
- Trial name
- NCT03314389
- Testing
- Cochet bonnet esthesiometer
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
FMF, Colchicine Resistance
Colchicine Levels in the Serum of FMF (Familial Mediterranean Fever) Patients
in this study the investigators will measure the colchicine trough levels in 80 FMF patients taking stable doses of colchicine
- Conditions
- FMF, Colchicine Resistance, Colchicine Toxicity
- Trial name
- NCT03210610
- Testing
- colchicine level measurement
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Sheba Medical Center
Diabetes, Older Diabetic Persons Without Dementia
CCT for Older Diabetic Adults
The current study examines the efficiency of a home-based computerized cognitive training (CT) intervention targeting older adults with diabetes.The primary aim of the study is to evaluate the effects of CCT on cognitive and…
- Trial name
- NCT02709629
- Testing
- Individualized and adaptive computerized cognitive training, Active control
- Where
- Israel
- Volunteers
- 85 people
- Sponsor
- Sheba Medical Center
Stem Cell Transplant Complications, Graft Versus Host Disease, Acute
Fecal Microbiota Transplantation for Steroid Resistant and Steroid Dependent Gut Acute Graft Versus Host Disease
The investigators hypothesize that perturbations in the intestinal microbiota following allogeneic hematopoietic stem cell transplantation (HSCT) are essential for the development and propagation of acute graft-versus-host…
- Conditions
- Stem Cell Transplant Complications, Graft Versus Host Disease, Acute, Fecal Microbiota Transplantation
- Trial name
- NCT03214289
- Testing
- Fecal Microbiota Transplantation
- Where
- Israel
- Volunteers
- 4 people
- Sponsor
- Sheba Medical Center
Acute Coronary Syndrome, Platelet Function and Reactivity Tests
Aspirin Impact on Platelet Reactivity in Acute Coronary Syndrome Patients on Novel P2Y12 Inhibitors Therapy
Thus far, no study has evaluated the impact on aspirin in addition to the newer and more potent P2Y12 inhibitors, among ACS patients and current guidelines recommend dual anti-platelet therapy consisting of aspirin and a novel…
- Conditions
- Acute Coronary Syndrome, Platelet Function and Reactivity Tests, Novel P2Y12 Inhibitors
- Trial name
- NCT02049762
- Testing
- Aspirin
- Where
- Israel
- Volunteers
- 29 people
- Sponsor
- Sheba Medical Center
Morbid Obesity, Satiety
Functional MRI Evaluation of Brain Response to Visual Food Stimulation in Morbidly Obese Patients Before and After Bariatric Surgery
Aim of study: To evaluate changes in feeding-related neural activity after different bariatric procedures in morbidly obese patients. Relationship of gut hormone levels will be assessed as well.
- Trial name
- NCT01140711
- Testing
- fMRI imaging following visual stimulation of food and non-food images
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Alzheimer's Disease (AD)
Cognitive-motor Intervention Using Virtual Reality for Middle-aged Individuals at High Dementia Risk
The primary objective of this program is to apply a virtual reality (VR) cognitive-motor intervention (compared to active and passive control groups) to delay or slow cognitive decline of middle-aged adults who have a family…
- Trial name
- NCT02832921
- Testing
- cognitive training by virtual reality, watching a scientific TV documentary, treadmill
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Artificial Heart Device User
Impact of Fluid and Passive Leg Raising on Cardiac Output in Patients Undergoing Cardiac Surgery
Left Ventricular Assist Device (LVAD) implantation is a common surgical procedure in patients with end-stage heart failure. Optimal fluid management is essential for adequate postoperative treatment.
- Trial name
- NCT03179033
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Coronary Disease With Diabetes Mellitus
Effects of SGLT2 Inhibitor in Diabetic Patients With Coronary Artery Disease
The aim of this study is to explore the effect of newly added SGLT2I medication or placebo, to standard medication regimen in diabetic patients with documented stable coronary disease.
- Trial name
- NCT03398577
- Testing
- Dapagliflozin 10 MG [Farxiga]
- Where
- Israel
- Volunteers
- 61 people
- Sponsor
- Sheba Medical Center
Eyelid Movement Disorders, Eyelid Ptosis Congenital
Müller's Muscle as a New Proprioceptive Organ
Objectives: Upper eyelid retraction was believed to be maintained solely by voluntary contraction of the levator palpebrae superioris (LPS) and frontalis muscles, together with involuntary contraction of the sympathetically…
- Trial name
- NCT03396627
- Testing
- pathological examination
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Ptosis, Eyelid, Ptosis; Eyelid, Congenital
Modified Müller's Muscle-conjunctival Resection Internal Ptosis Repair Using Fibrin Glue
Fibrin glue is widely used in ophthalmology for homeostasis and tissue recovery. It is commonly used in ocular surface surgeries such as pterygium removal and conjunctival lesions excisions.
- Conditions
- Ptosis, Eyelid, Ptosis; Eyelid, Congenital, Surgical Procedure, Unspecified
- Trial name
- NCT03392272
- Testing
- Using of Tisseel fibrin glue, Using sutures
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Tachycardia-induced Cardiomyopathy
Role of the Wearable Cardioverter Defibrillator in Tachycardia Induced Cardiomyopathy
The purpose of this current study is to prospectively enroll consecutive patients hospitalized with newly diagnosed severe left ventricular dysfunction (LVEF ≤ 35%) for which the likely etiology is uncontrolled atrial…
- Trial name
- NCT03388905
- Testing
- Life Vest Wearable defibrilator
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Schizophrenia
Add-on Methotrexate for the Treatment of Schizophrenia
A recent double-blind placebo-controlled study has tested the effect of methotrexate as an add-on treatment for patients with schizophrenia or schizoaffective disorder, administering 10 mg of methotrexate or placebo once a week…
- Trial name
- NCT03369795
- Testing
- Methotrexate
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Acute Coronary Syndrome, Smoking Cessation
Early In-hospital Initiation of Pharmacotherapy for Smoking Cessation, Patients After ACS
The hypothesis of this study is that combination of Varenicline treatment with nurse-led hospital support during hospitalization and after discharge will result in clinically significant higher long term abstinence rates in…
- Trial name
- NCT02106637
- Testing
- Varenicline
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Late Effects of Cerebrovascular Accident
Main Idea Perception of Written Stories and in Pictures Among Impaired Right Hemisphere Patients
Main idea perception of written stories and in pictures among impaired right hemisphere patients Abstract The right hemisphere is considered to complement the language processing abilities of the opposite hemisphere; it is…
- Trial name
- stroke (NCT02897791)
- Testing
- written evaluations
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Coronary Artery Disease
Effect of an Educational Intervention on Cardiac Patients' Participation Rate in Cardiac Rehabilitation Programs
The main aim of the study is to determine the effectiveness of an educational intervention designed to increase attendance of coronary artery bypass grafting (CABG) patients at Cardiac Rehabilitation Programs (CRPs) on actual CRP…
- Trial name
- MECRIS (NCT00356863)
- Testing
- Increasing awareness to cardiac rehabilitation programs
- Where
- Israel
- Volunteers
- 1,024 people
- Sponsor
- Sheba Medical Center
Brain Neoplasms
Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy
Recurrent brain tumours are extremely aggressive and despite optimal treatment, median survival is less than two years. One of the standard treatment options in this situation is radiation therapy.
- Trial name
- SMC 0712-13 (NCT02149459)
- Testing
- Partial brain re-irradiation., Metformin, low carbohydrate diet
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Sheba Medical Center
Healthy Volunteers, Effect of CPAP on Chest Movement
Effect of CPAP on Breath Hold and Chest Movement in Normal Volunteers
CPAP will be applied to normal volunteers inorder to understand CPAP's effects on breathing and chest wall motion.
- Trial name
- CPAP_normal (NCT02545686)
- Testing
- Chest wall movement assessment without CPAP, Breath hold assessment without CPAP, Chest wall movement assessment with CPAP
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Metabolic Syndrome Obesity
Melatonin Levels and the Relation to Obesity and the Metabolic Syndrome in Children and Adolescents
Background: Melatonin is a neurohormone that regulates the circadian rhythm by translating photoperiodic information from the eyes to the brain.
- Trial name
- NCT03316989
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center