Clinical trials: sponsored by Sheba Medical Center
Sleep Deprivation
The Effect of Partial and Complete Sleep Deprivation on Heat Tolerance
The purpose of the present study is to evaluate the effect of partial and complete sleep deprivation on exercise heat tolerance. Twelve healthy young male volunteers will participate in the study.
- Trial name
- NCT01596543
- Testing
- partial and complete sleep deprivation
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Body Temperature Changes
The Effect of Ventilated Vest on Thermoregulation During Exercise in Hot Environment
The purpose of this preliminary experiment is to measure the effect of a novel ventilation system on the physiological strain during exercise in high heat load while wearing ballistic protective vest.
- Trial name
- NCT01863927
- Testing
- Research intervention
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Heat Illness
Examination of a New Non Invasive Sensor "Lifebeam" During HTT in Protective Clothing
CB (Chemical Biological)protective clothing provides a thermal resistance between the human body and its environment. CB protective clothing will be essential for combat soldiers in case of non conventional attacks.
- Trial name
- lifebeam (NCT01789931)
- Testing
- "Lifebeam"
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
To Demonstrate That the Closed Loop System Can be Used Safely Over a Few Consecutive Days., To Assess Effectiveness in Maintaining Patients' Glucose Levels in the Target Range of 70 to 180 mg/dl, Measured by Blood Glucose Sensor.
Multiday Fully Closed Loop Insulin Delivery in Monitored Outpatient Conditions
Insulin replacement therapy is absolutely required for patients with Type 1 diabetes. The insulin pump provides for continuous subcutaneous insulin infusion (CSII), which can approximate the insulin release patterns of the normal…
- Conditions
- To Demonstrate That the Closed Loop System Can be Used Safely Over a Few Consecutive Days., To Assess Effectiveness in Maintaining Patients' Glucose Levels in the Target Range of 70 to 180 mg/dl, Measured by Blood Glucose Sensor., To Evaluate the User Experience With a Closed Loop System
- Trial name
- NCT02127827
- Testing
- Automated Ambulatory Glycemic Controller (AAGC)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Cumulative Trauma Disorders
Musculoskeletal Injuries' Prediction Tool for Military Combatants in the Israeli Defense Force
Emerging evidences indicate that performance on a variety of functional movement screens can identify athletes/soldiers at risk for injury.
- Trial name
- FMS (NCT02091713)
- Testing
- Functional movement screen
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Body Temperature Regulation
Physiological and Molecular Influences of Astaxanthin Supplementation on Heat Strain in Humans
Exposure to heat stress can compromise the physiological and cognitive function and be life threatening, particularly in a military setting.
- Trial name
- Astaxanthin (NCT02088242)
- Testing
- Astaxanthin
- Where
- Israel
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Premature Birth, Brain Injuries
S100B as a Marker of Brain Injury of Preterm Infants
The improvement of treatment of preterm neonates improved their survival, however there is still significant portion of preterm infants (specifically very preterm infants) that suffers from brain insults and as a result…
- Conditions
- Premature Birth, Brain Injuries, Leukomalacia Periventricular, Developmental Disabilities
- Trial name
- PTS100B (NCT02082535)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Bidirectional Endoscopy
Single Center Open Prospective Study for the Comparison of Procedural Sequence in Same Day Consecutive Bidirectional Endoscopy
The investigators study aim is to determine whether there is a any advantage in starting with upper or lower endoscopy. The main study objective will be the amount of analgesia needed for sustaining the examinee's comfort during…
- Trial name
- NCT01491126
- Where
- Israel
- Volunteers
- 170 people
- Sponsor
- Sheba Medical Center
Gastroparesis
IS There a Correlation Between Sypmtoms of Gastroparesis and the Duration of Video Caspule Retention in the Stomach
Gastroparesis is a syndrome characterized by delayed gastric emptying in absence of mechanical obstruction of the stomach. The cardinal symptoms include postprandial fullness (early satiety), nausea, vomiting, and…
- Trial name
- NCT01858220
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Lung Cancer
The Contribution of Induced Glycolysis to the Exhaled Volatile Organic Compounds' (VOCs) Signature in Lung Cancer
Lung cancer is the most lethal cancer, killing ~1.3 million people worldwide every year. Early diagnosis could increase its survival by 3-4 folds.
- Trial name
- NCT01852838
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Sheba Medical Center
Cerebral Palsy, Preterm Birth
Infant Aquatics Neurodevelopment Premature Infants
The objective of this research is to examine the effect of Infant Aquatics on the development of and neurodevelopment of preterm and near-term infants, using the GM as prognostic estimation of future development.
- Conditions
- Cerebral Palsy, Preterm Birth, Development
- Trial name
- IA-NPI (NCT01779661)
- Testing
- Infant Aquatics, Infant Massage
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Heart Failure
MADIT-CRT LONG-TERM INTERNATIONAL FOLLOW-UP REGISTRY - EUROPE
The registry is designed to determine the long-term mortality and morbidity benefit as a result of Cardiac Resynchronization Therapy with Defibrillation (CRT-D) vs.
- Trial name
- NCT02060110
- Testing
- Patients that were randomized to the the cardiac resynchronization therapy with defibrillation (CRT-D) device for the study, MADIT-CRT ICD ONLY ARM
- Where
- Israel
- Volunteers
- 447 people
- Sponsor
- Sheba Medical Center
Cystic Fibrosis
Cough Efficiency in Cystic Fibrosis
The major causes of morbidity and mortality in Cystic Fibrosis (CF) are linked to the process of chronic inflammatory of the airway, leading to the progressive damage of the small bronchioles and subsequently to the proximal…
- Trial name
- NCT01636219
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Rett Syndrome
An Open Label, Exploratory Study to Investigate the Treatment Effect of Glatiramer Acetate on Girls Woth Rett Syndrome
Primary Objective: To test the hypothesis that 6 months treatment with glatiramer acetate (GA) decreases epileptiform activity in young girls with Rett syndrome.
- Trial name
- NCT02023424
- Testing
- Glatiramer Acetate (Copaxone®)
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Post Traumatic Stress Disorder
A Correlation Between Hair Cortisol Levels and the Development of Post Traumatic Stress Disorder (PTSD)
This observational study follows subjects who have been exposed to a traumatic event and are at risk of developing PTSD symptoms.
- Trial name
- NCT02033395
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Schizophrenia, Obsessive Compulsive Disorder
Treatment With Ziprasidone for Schizophrenia Patients With Obsessive Compulsive Disorder (OCD)
Comparing schizophrenic patients with comorbid OCD and schizophrenic patients without OCD in response to Ziprasidone and in cognitive functioning as compared with OCD patients
- Trial name
- NCT00229385
- Testing
- Ziprasidone
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Sheba Medical Center
Post-traumatic Stress Disorder
PTSD Prevention Using Escitalopram
Assessing the efficacy of escitalopram in preventing the development of PTSD, or or reducing its severeness, after exposure to a traumatic event.
- Trial name
- NCT00300313
- Testing
- Escitalopram
- Where
- 5 sites in Israel
- Volunteers
- 450 people
- Sponsor
- Sheba Medical Center
Body Temperature Regulation
Non-invasive Sensor for Core Temperature Measurement
Soldiers are required to perform and maintain alertness in difficult environmental conditions. The sensor examined in this trail may indicate body core temperature elevation during exertion.
- Trial name
- Drager (NCT02017184)
- Testing
- Noninvasive core temperature thermistor
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Retinitis Pigmentosa
The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions im Patients With Retinitis Pigmentosa
Retinitis pigmentosa is a genetically determined disease consisting of progressive centripetal retinal degeneration starting in the rods outer segments.
- Trial name
- NCT01256697
- Testing
- Alga Dunaliella Bardawil, Alga Dunaliella Bardawill, Sugar pill
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Sheba Medical Center
Heat Stroke, Healthy
The Development Of A Novel Biomarker For Early Identification Of The Individual's State Of Tolerance To Heat
Today, the level of tolerance to heat is based on physiological strain indices, with no correlates to any relevant biomarker. We hypothesize that oxidative stress (OS) and the formation of reactive oxygen and nitrogen species…
- Trial name
- NCT01290159
- Testing
- heat tolerance test (HTT)
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center