Clinical trials: sponsored by Sheba Medical Center
Verifying the Correct Position of Intravenous Catheters
Intravenous Sodium Bicarbonate Verifies Intravenous Position of Catheters in Children
Sodium bicarbonate injected into a blood vessel transforms to carbon dioxide and water. The increase in carbon dioxide production can be detected by measuring the exhaled carbon dioxide in the lungs.
- Trial name
- NCT01409083
- Testing
- intravenous sodium bicarbonate
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Sheba Medical Center
IDIOPATHIC PULMONARY FIBROSIS
The Role of Gastric Content Microaspirations in the Pathogenesis of Idiopathic Pulmonary Fibrosis
The pathogenesis of idiopathic pulmonary fibrosis (IPF) is debatable. Looking for an insult to lung parenchyma that generates the pathogenesis of the disease is challenging.
- Trial name
- NCT01714934
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Stroke
Evaluation of the Gertner Tele-Motion-Rehabilitation System for Stroke Rehabilitation
The overall goal of the study is to evaluate the clinical effectiveness of a home-based tele-motion-rehabilitation (TMR) program in improving functional status of people who had stroke.
- Trial name
- GertnerTMR (NCT01655264)
- Testing
- Home-based self training exercises for weak upper extremity, Tele-rehabilitation exercises for weak upper extremity
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Sheba Medical Center
Post Traumatic Stress Disorder, Sleep Deprivation
Explanation About Sleep in Post Trauma Patients
This study is designed to test the effect of an explanation about the first sleep following trauma exposure, on the development of Post Traumatic Stress Disorder (PTSD) in the months following the traumatic event.
- Trial name
- NCT01684085
- Testing
- Explanation encouraging sleep, Explanation discouraging sleep, Lorazepam
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Persons With Frontal Lobe Damage With no Specific Language Disorder
Evaluation of Mental Flexibility Through Language Tests in Adolescents With Frontal Brain Damage and in Healthy Children in Ages 8-17
This study aims to shed light on the theoretical concept of mental flexibility and its manifestation in adolescents following frontal lobe damage, and to develop a test battery for young Hebrew speakers.
- Trial name
- NCT01696292
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Pulmonary Edema, Cerebral Edema
Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention
To evaluate the additive value of tadalafil given together with Diamox (acetazolamide) in preventing acute mountain sickness in travelers to high altitude areas.
- Trial name
- NCT01060969
- Testing
- Tadalafil and acetazolamide, Acetazolamide
- Where
- 3 sites in Israel
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Aneurysm, Hypertension
The Effect of Angiotensin II Type 1 Receptor Antagonists on the Size and Expansion Rate of Abdominal Aortas in Hypertensive Patients
Abdominal aortic aneurysm (AAA) is a common disease that develops from degeneration of the aortic wall. The natural history of AAA is gradual expansion and if left untreated may result in rupture and death.
- Trial name
- NCT01670903
- Where
- 2 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Hemophilia A
Combination Therapy of Low Doses of rFVIIa and FEIBA for Severe Hemophilia A Patients With an Inhibitor to Factor VIII
Patients with severe hemophilia and inhibitors can be treated effectively by Activated Prothrombin Complex Concentrates (APCC, eg. FEIBA) or High dose recombinant factor VIIa (rFVIIa).
- Trial name
- NCT00284193
- Testing
- rFVIIa-FEIBA therapy for hemophilia A inhibitors, FEIBA- Activated Prothrombin Complexes
- Volunteers
- 5 people
- Sponsor
- Sheba Medical Center
Night Blindness
Treatment of Congenital Stationary Night Blindness With an Alga Containing High Dose of Beta Carotene
To assess the effect of oral administration of the alga Dunaliella bardawil containing approximately 50% all-trans beta-carotene and 50% 9-cis beta-carotene isomers on visual functions patients with Congenital Stationary Night…
- Trial name
- NCT00569023
- Testing
- alga Dunaliella bardawil
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Sheba Medical Center
Psoriasis
The Effect of Alga Dunaliella Bardawil on Psoriasis
This is a double blind, parallel group, randomized study with 12 weeks of daily oral administration of Dunaliella or placebo in psoriasis patients.
- Trial name
- NCT01628081
- Testing
- Dunaliella Bardawil
- Where
- 2 sites in Israel
- Volunteers
- 46 people
- Sponsor
- Sheba Medical Center
Traumatic Brain Injury
Study of Reserves After Traumatic Brain Injury
It is hypothesized that the long-term results of rehabilitation and subsequent aging after Brain Trauma depend on brain's premorbid anatomical (structural) and functional (cognitive, emotional) reserves.
- Trial name
- NCT01628003
- Testing
- Brain MRI, MRI
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Diabetes Mellitus 2 Type
Comparison of Two Insulin Regimens in Optimally-controlled Patients With DM2.
Intensive Insulin Therapy (IIT) may be given in Type 2 Diabetes (T2DM) in two different ways : as Basal/bolus therapy (B/B) in four-five injections per day . as Modern Premixed Insulins( MPI's) three times per day .
- Trial name
- NCT01627509
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Impaired Balance in Elderly
Pilot Study of AdvanStep in Improving Balance in at Risk Elderly
Elderly individuals are often at increased risks for falls. The AdvanStep is an interactive training exercise and balance device.
- Trial name
- AdvanStep (NCT01059253)
- Testing
- AdvanStep training program - Turtle Pop
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Hip Fracture
Troponin Elevation in the Elderly Patient With Hip Fracture
Elevated troponin is powerful and independent adverse prognostic marker in patient with ACS. However, non specific (non cardiac) troponin elevation is a common finding among hospitalized patients and worse prognosis too.
- Trial name
- NCT00647309
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Anxiety
The Effects of Pre-operative Magic Tricks Performance on Pre-operative Anxiety in Children
It is not uncommon for children to undergo surgery. Surgery is a threatening event that is composed of various stress-provoking stimuli.
- Trial name
- NCT00535457
- Testing
- Preoperative Magic Tricks
- Where
- Israel
- Sponsor
- Sheba Medical Center
Duration of Preoperative Fasting
The Influence of Education of Medical Team on Duration of Fasting Before Elective Medical Interventions Performed Under General Anesthesia in Children
The purpose of the study is to examine if an education program of the medical teams can help implementation of of NPO (nothing-per-os)orders in children before anesthesia for ambulatory medical interventions under anesthesia and…
- Trial name
- NCT00545636
- Testing
- education
- Where
- Israel
- Sponsor
- Sheba Medical Center
Cerebrotendinous Xanthomatosis (CTX)
Evaluation of Carotid IMT and Atherogenic Risk Factors in Patients With Cerebrotendinous Xanthomatosis
The aim of the proposed study is to evaluate the risk for cardiovascular disease and 'atherogenic' features of the serum in CTX and to determine preclinical atherosclerosis.
- Trial name
- CTX (NCT01613898)
- Testing
- Blood tests
- Where
- Israel
- Volunteers
- 17 people
- Sponsor
- Sheba Medical Center
Obesity
A Multi-component Program to Reduce Obesity in Children
In an attempt to challenge the increasing prevalence of childhood obesity, many programs have been executed in order to improve childrens' lifestyle. Programs involved either school, family or environmental measures.
- Trial name
- NCT00747513
- Testing
- lifestyle program
- Where
- 22 sites in Israel
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Mania
Allopurinol for Mania: A Randomized Trial Administering Allopurinol vs. Placebo as add-on to Mood Stabilizers and/or Antipsychotics in Patients in a Bipolar Manic Episode
The objective of the study is to evaluate the efficacy of allopurinol, compared to placebo, as add-on to mood stabilizers and/or antipsychotic in the treatment of patients with bipolar disorder, in a manic episode.
- Trial name
- NCT01092221
- Testing
- Allopurinol
- Where
- 24 sites in Israel, Romania
- Volunteers
- 180 people
- Sponsor
- Sheba Medical Center
Schizophrenia, Schizoaffective Disorder
Allopurinol in Schizophrenia: A Randomized Trial Administering Allopurinol vs Placebo as add-on Antipsychotics in Patients With Schizophrenia
The objective of the study is to evaluate the efficacy of allopurinol, compared to placebo, as add-on to anti-psychotics in the treatment of patients with schizophrenia.
- Trial name
- NCT00864825
- Testing
- Allopurinol
- Where
- 33 sites in Israel, Romania
- Volunteers
- 248 people
- Sponsor
- Sheba Medical Center