Clinical trials: sponsored by Sheba Medical Center
Schizophrenia
Exercise and Diet Program for Schizophrenia Patients Who Are Taking Atypical Antipsychotic Medications
In this study the investigators will recruit patients with the diagnosis of schizophrenia that are taking atypical neuroleptics and that are willing to participate in an exercise and diet program.
- Trial name
- NCT01409590
- Testing
- Exercise program, Diet
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Healthy
Interruption of Dorsal Visual Stream Using TMS
Trans Cranial Magnetic Stimulation (TMS) over dorsal visual system will disturb the ability to identify objects with decreased level of fragmentation
- Trial name
- NCT00418652
- Testing
- No TMS intervention, TMS over the PO3 EEG site, TMS over the vertex
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Stroke
Enriched Environments for Upper Limb Stroke Rehabilitation
Stroke contributes significantly to the incidence of disabilities, with upper limb (UL) motor impairment being especially prevalent.
- Trial name
- NCT01388400
- Testing
- conventional occupational therapy, video capture virtual reality
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Colorectal Neoplasms
β-adrenergic Blocker and a COX2 Inhibitor for Prevention of Colorectal Cancer Recurrence
Colon and rectal cancer is the second most prevalent malignant disease in the western world, causing significant morbidity, mortality, and healthcare sources use.
- Trial name
- NCT00888797
- Testing
- Propranolol and Etodolac
- Where
- 3 sites in Israel
- Volunteers
- 400 people
- Sponsor
- Sheba Medical Center
Heavy Smoking
High-Frequency Repetitive Transcranial Magnetic Stimulation Assists In Smoking Cessation
Cigarette smoking is a major public health problem causing significant morbidity and mortality. Yet, smoking cessation therapies are often ineffective at helping smokers break their addiction.
- Trial name
- NCT00284219
- Testing
- Transcranial Magnetic Stimulation 10Hz
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Endometriosis
The Immune Base of Endometriosis
Endometriosis is a chronic disabling inflammatory disease which effects 15-20% of women in their reproductive life. In patients suffering from endometriosis retrograded menstrual cells induce an inflammatory…
- Trial name
- NCT00370123
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ataxia, Chorea
Amantadine for Improving Neurologic Symptoms in Ataxia-Telangiectasia
Ataxia-Telangiectasia A-T is a neurodegenerative disorder of the cerebellum, manifesting with ataxia, as well as extrapyramidal features.
- Conditions
- Ataxia, Chorea, Dystonia, Parkinsonism
- Trial name
- NCT00950196
- Testing
- amantadine sulphate
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Prostatic Neoplasms
Evaluation of MRI for Prostate Cancer
The objective of this study is to evaluate imaging quality and correlation with histopathology in prostate cancer.
- Trial name
- NCT00930748
- Testing
- MR imaging with endorectal coil, MRI with endo-rectal coil
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Schizophrenia
Evaluation of Dorsal Visual Stream in Patients With Schizophrenia
Schizophrenia patients in comparing to normal controls show decreased ability to identify objects with decreased level of fragmentation, a task that is associated with magnocellular pathway function.
- Trial name
- NCT01378403
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Sheba Medical Center
Work Related Musculoskeletal Disorders
Efficacy of Telerehabilitation Intervention Program Using Telebiofeedback Among Computer Operators
In the recent decades, with technology development, computer workstation has become fundamental both at work and at home environments, and is now used routinely for many purposes.
- Trial name
- NCT01178983
- Testing
- surface electromyography
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Stroke
Virtual Reality Training Program for Ambulatory Patients With Chronic Gait Deficits After Stroke
The purpose of this study is to examine the feasibility and efficacy of a virtual reality program for ambulatory patients with mild-to-moderate chronic gait deficits after stroke.
- Trial name
- NCT00600379
- Testing
- Virtual reality system (CAREN™ Integrated Reality System; MOTEK BV, Netherlands).
- Where
- Israel
- Volunteers
- 48 people
- Sponsor
- Sheba Medical Center
Healthy Subjects, Hypomagnesemia
The Absorption of Magnesium Oxide Compared to Citrate in Healthy Subjects
The magnesium food content in the Western world is consistently reducing. Hypomagnesemia is common in hospitalized patients, especially in the elderly with coronary artery disease (CAD) and/or those with chronic heart failure.
- Trial name
- NCT00994006
- Testing
- Magnesium oxide, Magnesium citrate
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Schizophrenia, Schizoaffective Disorder
Minocycline, Acetylsalicylic Acid or Pramipexole vs Placebo in Patients With Schizophrenia or Schizoaffective Disorder
The objective of the study is to evaluate the efficacy of Pramipexole, Minocycline and Aspirin compared to placebo, as add-on to anti-psychotics in the treatment of patients with schizophrenia.
- Trial name
- MAP-S-01 (NCT01320982)
- Testing
- minocycline, pramipexole, acetylsalicylic acid
- Where
- 14 sites in Israel, Romania
- Volunteers
- 400 people
- Sponsor
- Sheba Medical Center
Central Hypothyroidism
Central Hypothyroidism, a Novel Laboratory Measurement
Medical management of central hypothyroidism is controversial due to lack of reference for evaluation of pituitary negative feedback.
- Trial name
- NCT01280292
- Testing
- Eltroxin
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Schizophrenia, Schizoaffective Disorder
Raloxifene in Treatment of Schizophrenia and Schizoaffective Disorder
The objective of the study is to evaluate the efficacy of raloxifene compared to placebo, as add-on to anti-psychotics in the treatment of post menopausal patients with schizophrenia.
- Trial name
- RAL-S-01 (NCT01280305)
- Testing
- raloxifene
- Where
- 13 sites in Israel, Romania
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Chronic Hepatitis C
Clinical Trial to Assess Safety and Efficacy of Combination Therapy: Hydroxychloroquine, Pegylated Interferon Alpha-2a and Ribavirin in Chronic Hepatitis C Subjects Non-responders to the Standard of Care Therapy.
The study is aimed to investigate the safety, tolerability and efficacy of a fixed dose combination therapy of: Hydroxychloroquine (HCQ), Pegylated Interferon Alpha-2a (PEG-IFN alpha-2a) and Ribavirin (RBV) in Chronic Hepatitis C…
- Trial name
- NCT01272310
- Testing
- Hydroxychloroquine (HCQ), Pegylated Interferon Alpha-2a (Peg-IFN alpha-2a) and Ribavirin
- Volunteers
- 36 people
- Sponsor
- Sheba Medical Center
Burn's Associated Contracture
Injectable Collagenase For Burns' Associated Contracture
A pilot experiment to test the efficiency of the enzyme Collagenase in treating contractures which result's from burn's healing process.
- Trial name
- NCT01237964
- Testing
- Xiaflex (FDA approved collagenase)
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Cerebral Palsy, Cortical Visual Impairment
Cortical Visual Impairment and Visual Attentiveness
This study will investigate the effect of enhanced visual and cross-modal environments upon the visual attentiveness of multiply handicapped children diagnosed with Cerebral Palsy (CP) and Cortical Visual Impairment (CVI).
- Trial name
- NCT00342108
- Testing
- cross-modal sensory stimulation
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Stress Disorders, Post-Traumatic, Retinal Detachment
Diagnosis of Posttraumatic Stress Disorder Following Primary Rhegmatogenous Retinal Detachment
To investigate the prevalence of posttraumatic stress disorder (PTSD) in patients that underwent surgery for primary rhegmatogenous retinal detachment (RRD) and to determine variables associated with the disorder.
- Trial name
- NCT01233908
- Where
- Israel
- Volunteers
- 547 people
- Sponsor
- Sheba Medical Center
General Anesthesia
Intravenous Sodium Bicarbonate Verifies Intravenous Position of Catheters in Anesthetized Children
Extravasation is an unintentional injection or leakage of fluids in the perivascular or subcutaneous space. Extravasation can be associated with tissue injury with various level of severity and long term consequences.
- Trial name
- NCT01219322
- Testing
- Sodium bicarbonate, normal saline
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center