Clinical trials: sponsored by Sheba Medical Center
Femoral Neck Fractures
Intracapsular Femoral Neck Fractures Fixation With a Dynamic Locking Plate and Screw System, Targon FN
The purpose of this study is to evaluate our experience in internal fixation of intracapsular femoral neck fractures with the Targon FN implant prospectively and retrospectively in terms of the outcomes and complications…
- Trial name
- NCT00830687
- Testing
- TARGON FN
- Where
- 3 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Femoral Neck Fractures
Comparison Study of 3-4-screws-internal Fixation With Multi-screw-system Targon FN for Femoral Neck Fracture
The purpose of this study is to compare between two methods of internal fixation, the 3-4 parallel screws or the Targon FN implant in gardens type 1-2 or Pauwels type 1-2 femoral neck fractures in terms of the outcomes and…
- Trial name
- NCT00829725
- Testing
- screws-internal fixation, TARGON FN
- Where
- 3 sites in Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Common Melanocytic Nevi
Classification and Longitudinal Follow-up of Common Melanocytic Nevi With in Vivo Reflectance Confocal Microscopy
Our working hypothesis is that reflectance confocal microscopy (RCM) can identify distinct subsets of melanocytic nevi that retain their distinctive pattern over time.
- Trial name
- NCT01194947
- Testing
- RCM imaging
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Sheba Medical Center
Antibiotic Use, Carriage of Antibiotic Resistant Pathogens
Israeli Judicious Antibiotic Prescription Study
This study aims to implement judicious antibiotic prescription habits to primary care pediatricians using a multifacet educational intervention and assess two main outcomes: 1) Direct outcome - prescription rates of the…
- Trial name
- IJAP (NCT01187758)
- Testing
- Workshops and focus group meetings
- Volunteers
- 5,700 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Observational
Progression of Renal Amyloidosis of FMF and Relation to Serum SAA Level
Purpose of this study is to determine whether keeping SAA on normal or near normal level will delay progression of renal failure in patients with amyloidosis secondary to FMF.
- Trial name
- NCT01168570
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Pregestational Diabetes
Intrapartum Maternal Glycemic Control Using Insulin Pump Versus Insulin Drip - Cohort Observational Trial
The purpose of this study is to compare intrapartum glycemic control using insulin pump versus intravenous (IV) insulin administration.
- Trial name
- NCT01158040
- Where
- Israel
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Alopecia Areata
Comparative Study Examining the Effectiveness in Use of a DERMOJET and a Normal Syringe Treatment for Patients With Hair Loss - Alopecia Areata
Conventional treatments include the use of steroids applied locally, or injection in to the legion, or oral therapy. Treatment is determined by the severity of the disease. Injection in to the legion can be done in two methods 1.
- Trial name
- NCT01017510
- Testing
- Subcutaneous injection luer syringe, DERMOJET (a syringe without a needle)
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Healthy, Hypertrophic Pyloric Stenosis
The Effect of Hypertrophic Pyloric Stenosis (HPS) on Sodium Intake in Childhood
The loss of sodium during infancy causes long term changes in sodium intake. Human research shows that the loss of maternal sodium during pregnancy and neonatal after birth causes an increase sodium intake during childhood.
- Trial name
- NCT01159509
- Testing
- sodium taste tests
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Clinical Workload Assessment Based Upon a Home Monitoring System
Sheba Medical Center Home Monitoring Clinic Registry
The purpose of the registry is to assess workload of a Home Monitoring based follow up for Biotronik ICD and CRTD patients.
- Trial name
- NCT01154205
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Skin Cancer
Confocal Microscopy of Benign and Malignant Skin Tumors
The investigators speculate that this tool may be used as an alternative and convenient non-invasive diagnostic of skin cancer.
- Trial name
- NCT01010321
- Testing
- confocal microscopy
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Cord Blood Amino Acid Profile, Fetal Amino Acid Profile in Different Gestational Ages
Amino Acid Profile in the Fetus and the Neonate
Up-to-date, the preterm newborn nutrition is based on human breast milk or it's imitations. However, the growth rate is known to be reduced compared to the fetal growth rate.
- Conditions
- Cord Blood Amino Acid Profile, Fetal Amino Acid Profile in Different Gestational Ages, Infant Amino Acid Profile at Day 3 and Discharge
- Trial name
- NCT01140698
- Testing
- Blood sample on Guthrie paper from cord blood, and day 3 of life and before discharge
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Iron Overload
Fetal Parenchymatic Evaluation (Liver, Spleen) Using T2* Sequences
The purpose of this study is to prospectively evaluated the T2* values of normal feti.A standardized scale of T2* values for fetal and neonatal iron organ overload have yet to be reported or devised.
- Trial name
- NCT01121094
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy
Implementation of Work in Progress (WIP) Sequences in Magnetic Resonance Imaging (MRI)
Trial of new work in progress (WIP) sequences in MRI.
- Trial name
- NCT01019226
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Sheba Medical Center
Iron Overload
MRI Evaluation of Iron Overload in the Heart, Liver and Pancreas in Patients Receiving Multiple Blood Transfusions.
Sickle cell anemia and Sickle cell β thalassemia patients require multiple transfusions in order to avoid chronic anemia sequel.
- Trial name
- NCT00629291
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Bone Density
Bone Density of Large Newborn Infants and Infants of Diabetic Mothers
Bone density was found to be impaired among lage babies and infants of diabetic mothers as found in small group studies. The assumption is that large weight decreases fetal movements and causes decreased bone mineralization.The…
- Trial name
- NCT01117324
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Ataxia Telangiectasia
Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia Patients
Ataxia-telangiectasia (AT) is a rare genetic disorder characterized by gait disorders, neuromotor dysfunction, eye abnormalities and immune deficiency.
- Trial name
- NCT01075438
- Testing
- Prevenar® (7-valent pneumococcal conjugate vaccine), Pneumovax® (pneumococcal polysaccharide vaccine)
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Oral Lichen Planus
The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus
The aim of the present study is to assess the clinical efficacy of topical minocyclin in managing of symptoms associated with oral lichen planus (OLP).
- Trial name
- NCT01083420
- Testing
- Minocycline, Dexamethasone
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Coronary Disease
The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart Disease
Prior work (Chris, M. et al, Clinical Science 2005; 109, 55-60) has demonstrated that drinking a cup of coffee (80-100 mg of caffeine) an hour before endothelium-dependent FMD (flow-mediated dilatation) of the brachial artery…
- Trial name
- NCT00564824
- Testing
- Caffeine
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Healthy, Strain
Mechanical Load on the Shoulders While Carrying a Backpack- Towards a Knowledge-Based Backpack Design
Soldiers and recreational backpackers are often required to carry heavy loads on their body during military operations or hiking.
- Trial name
- NCT01066975
- Where
- Israel
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Depressive Disorder, Major
A Naturalistic Study of the Efficacy and Safety of Escitalopram in Treatment Resistant Depression
The primary objective of this multicenter study is to evaluate the efficacy of escitalopram in treatment resistant depression (TRD), assessed by 2 consecutive failed antidepressant treatments from different classes.
- Trial name
- NCT00220480
- Testing
- escitalopram
- Where
- 4 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center