Clinical trials: sponsored by Sheba Medical Center
Low HDL Cholesterol
The Effect of the Alga Dunaliella Bardawil as a Source of 9-cis Retinoic Acid on Lipid Profile in Fibrate Treated Patients.
The effect of fibrates on high density lipoprotein (HDL)-cholesterol levels is suggested to be mediated by its binding to peroxisome proliferator-activated receptor-g (PPARg).
- Trial name
- NCT00156169
- Testing
- Dunaliella
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Ataxia Telangiectasia
The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied Longitudinally
Rationale: Forced spirometry maneuvers are not routinely performed in patients with Ataxia Telangiectasia (A-T), even though they suffer from respiratory illnesses.
- Trial name
- NCT00951886
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Sheba Medical Center
Hormone Refractory Prostate Cancer
Efficacy of FWGE in Combination With Hormone Therapy for the Treatment of Hormone-Refractory Prostate Cancer Patients
We propose in this study to treat hormone refractory prostate cancer (HRPC) patients., with a novel preparation of fermented wheat germ nutriment (FWGE), in combination with the 1st line hormone therapy, the gonadotropin…
- Trial name
- NCT00411853
- Testing
- Fermented Wheat germ extract
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Pain
The Effect of Acupuncture Treatment on the Perception of Pain and Coping With Pain
The Purpose of this study is to evaluate whether cognitive and emotional components take part in the positive acupuncture effect on pain.
- Trial name
- NCT00369902
- Testing
- acupuncture
- Where
- Israel
- Volunteers
- 41 people
- Sponsor
- Sheba Medical Center
Efficacy, Complications
The Safety of Cataract Removal by Phacoemulsification Surgery in Patients Under Anti-aggregant and Coumadin Treatment
To assess the risks of intra- and postoperative bleeding tendency associated with cataract surgery by phacoemulsification in patients on coumadin and antiaggregant treatments. Design: Consecutive prospective study.
- Trial name
- NCT00564356
- Testing
- cataract surgery with phacoemulsification
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Sheba Medical Center
Recurrent Miscarriage
Investigation of Embryoscopy in Recurrent Pregnancy Loss
The purpose is to test the value of embryoscopy in women with missed abortions after recurrent miscarriages (at least two previous miscarriages) in the past. This project will assess two functions of embryoscopy:- 1.
- Trial name
- NCT00589446
- Testing
- Hysteroscope
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Hypertension, Kidney Transplant
Melatonin and Adiponectin in Hypertensive Kidney Transplant
Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome. We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients.
- Trial name
- NCT00498576
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Elective Cesarean Section, Maternal Hypotention
Maternal Hypotension During Cesarean Section and Short Term Neonatal Outcome.
About 20-25% of deliveries are by cesarean section. Most are elective with use of regional anesthesia (spinal/epidural). Drop of blood pressure after regional anesthesia is common.
- Trial name
- NCT00330512
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Newborn, Full Term
Follow up Glucose Levels Among Infants of Diabetic Mothers
Infants to diabetic mothers (IDM) are at risk for developing hypoglycemia after birth. Glucose level follow ups are recommended to each IDM.
- Conditions
- Newborn, Full Term, Diabetic Mother
- Trial name
- NCT00337142
- Volunteers
- 250 people
- Sponsor
- Sheba Medical Center
Graft Versus Host Disease
Ocular Graft Versus Host Disease After Hematopoietic Stem Cell Transplantation in Adults
The purpose of this study is to evaluate the presence and manifestations of ocular graft versus host disease in adults that had hematopoietic stem cell transplantation in the past 3 years at the sheba medical center, Israel.
- Trial name
- NCT00912067
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Sheba Medical Center
Shoulder Proprioception, Open Capsular Shift
Shoulder Proprioception Following Open and Arthroscopic Instability Repair
Shoulder dislocations are common and may result in functionally disabling instability. Disruption of the shoulder capsuloligamentous complex during shoulder dislocation is related to poor proprioceptive and stabilizing…
- Conditions
- Shoulder Proprioception, Open Capsular Shift, Arthroscopic Bankart Repair, Unrestricted Arm Movement
- Trial name
- NCT00889109
- Testing
- Three dimensional unrestricted arm movements
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Platlet Aggregation, Major Bleeding Outcomes
Chewing Clopidogrel in Addition to Regular Oral Clopidogrel Treatment to Improve Platelets Aggregation in Patient With NON ST ELEVATION MI
Since the absorption of clopidogrel through the gastrointestinal tract is limited, we want to examine whether adding clopidogrel by chewing will overcome the limited gastrointestinal absorption, and hence will improve the…
- Trial name
- NCT00889044
- Testing
- clopidogrel by chewing
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Crohn's Disease
Treatment of Perianal Crohn's Disease, Combining Medical and Surgical Treatment.
This study is aimed to assess the hypothesis that instillation of fibrin glue with the induction of local conditions using Infliximab, may be useful in the treatment of perianal Crohn's disease.
- Trial name
- NCT00252369
- Testing
- Infliximab, Instillation of fibrin glue
- Where
- 4 sites in Israel
- Sponsor
- Sheba Medical Center
Pregnancy
The Effect of Delivery Mode on Inter - Couple Relationship, Sexual Function and Pelvic Floor Activity
Pregnancy and delivery have a major impact on couple's inter personal relationship. Different modes of delivery have different effect on pelvic floor function, and it is known that instrumental vaginal deliveries have the worse…
- Trial name
- NCT00872040
- Testing
- Ultrasound assessment of pelvic floor
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Schizophrenia
Comparison of Cognitive Functions of Schizophrenic Patients Treated With Sertindole Versus Risperidone
In this study we intend to compare the effect of Sertindole to that of Risperidone on cognitive impairment in schizophrenia. Hypothesis: Sertindole will be as effective as Risperidone for treating cognitive impairment in…
- Trial name
- NCT00480844
- Testing
- Sertindole, Risperidone
- Where
- 3 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Coronary Artery Disease, Cardiac Perfusion
Stress Adenosine Cardiac Magnetic Resonance (MR) Comparison With Single Photon Emission Computed Tomography (SPECT) Imaging
This study is designed to determine the diagnostic value of adenosine cardiac magnetic resonance (CMR) when compared with SPECT.
- Trial name
- NCT00864591
- Testing
- SPECT Imaging, Stress Adenosine CMR
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Hip Fracture
Economic Aspects Associated With the Implementation of an Orthogeriatric Setting in a General Hospital
The economic and social burden of hip fractures is expected to increase dramatically, but financial resources remain limited. This calls for the investigation of innovative new forms of organization and integration of medical…
- Trial name
- NCT00860132
- Volunteers
- 2,000 people
- Sponsor
- Sheba Medical Center
Antibody Immune Profile
Study of the Development of Human Immune System of Newborns by Antigen Chips
The immune system is a dynamic, constantly evolving network. Excluding autoimmune diseases, healthy individuals are also known to have a large number of circulating antibodies that can recognize proteins of their own tissues.
- Trial name
- NCT00843648
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Urinary Stones
Management of Fragments During Ureteroscopy
The purpose of this study is to study the outcome of patients after ureteroscopy in which all fragments remaining after holmium laser lithotripsy were retrieved compared to those where small, insignificant fragments were left for…
- Trial name
- NCT00637650
- Testing
- Ureteroscopy, Holmium Laser lithotripsy and active retrieval of fragments, Ureteroscopy, Holmium laser lithotripsy, no intent to retrieve any remaining fragment
- Where
- Israel
- Sponsor
- The Chaim Sheba Medical Center
Macular Degeneration
The Effect of Intravitreal Avastin on the Retina Measured by Electroretinogram
To evaluate the scotopic and photopic ERG responses before and after one month of intravitreal avastin injection in patients with choroidal neovascularization.
- Trial name
- NCT00478530
- Testing
- ELECTRORETINOGRAM
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center