Clinical trials: sponsored by Sheba Medical Center
Familial Mediterranean Fever
Magnetic Resonance (MR) Spectroscopy In Familial Mediterranean Fever (FMF) Patients
Familial Mediterranean fever (FMF) is an inherited disorder of unknown etiology, characterized by recurrent episodes of fever, peritonitis and/or pleuritis.
- Trial name
- NCT00658060
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Coronary Artery Disease, Endothelial Function
The Association of Platelet Function and Endothelial Function of the Brachial Artery
The proposed study is a prospective one, and will be held on consecutive individuals undergoing the non-invasive brachial artery flow-mediated dilation (FMD) ultrasound for endothelial function at the endothelial function…
- Conditions
- Coronary Artery Disease, Endothelial Function, Thrombosis
- Trial name
- NCT00363818
- Where
- 2 sites in Israel
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cardiovascular Diseases
Pharmacogenetic Study of Warfarin Dose-Response: a Prospective Trial
We propose to develop a personalized pharmacogenetic approach including the major genetic markers of warfarin (coumadin) dosing and patients' age and weight.
- Trial name
- PGxWarfarin (NCT00654823)
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Sheba Medical Center
Major Depression, Diabetes Mellitus
Efficacy Study of Escitalopram for Depression in Patients With Diabetes
Patients with diabetes and major depression treated with Escitalopram might experience significant improvement in depression and anxiety scores; functional ability; diabetes-related self-care; and pain symptoms
- Trial name
- EFDID (NCT00650897)
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Cardiovascular Diseases
The Usefulness of the HyperQ Stress System in Routine Annual Screening Testing
The main objective of this study is to compare the sensitivity and specificity of a new system for analyzing the electrocardiogram (ECG) to the sensitivity and specificity of a conservative treadmill test in asymptomatic…
- Trial name
- NCT00266435
- Where
- Israel
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Amputations, Traumatic
Gait Evaluation of Experienced Below Knee Amputees
Post traumatic amputees with an experience of over 3 months of prosthesis use at home, without any known difficulty using the prosthesis and without stump pathology, using no assistive devices, will be examined in a 3 D…
- Trial name
- NCT00353626
- Where
- Israel
- Volunteers
- 9 people
- Sponsor
- Sheba Medical Center
Neovascular Age Related Macular Degeneration
The Effects of Bevacizumab and Ranibizumab on Ocular Pulse Amplitude in Neovascular Age Related Macular Degeneration (AMD)
One concern about repeated intravitreal injections of bevacizumab (Avastin) and ranibizumab (Lucentis) in wet age related macular degeneration, is that in addition to blocking the proteins that triggers the development and…
- Trial name
- AMD (NCT00640640)
- Testing
- Pascal Dynamic Contour Tonometer, Ranibizumab, Bevacizumab
- Where
- 2 sites in Belgium, Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Bladder Function
Unilateral Cutaneous Ureterostomy - Long Term Follow up
This observational study is aimed at exploring bladder function following temporary unilateral low loop cutaneous ureterostomy carried out in newborns suffering from severe congenital hydro-ureteronephrosis
- Trial name
- ureterostomy (NCT00546208)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Schizophrenia
Genetics of Schizophrenia
Genetic etiology in schizophrenia is widely accepted. However, many chromosomal sites were shown to characterize the families of patients with schizophrenia. This is probably due to the high genetic heterogenity of this illness.
- Trial name
- NCT00619437
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Hemiplegic Cerebral Palsy
The Influence of MCIMT (Modified Constrained Induced Movement Therapy), Bilateral Intensive Treatment, and NDT Approach on the UL Function in Children With Hemiplegic Cerebral Palsy
The purpose of this pilot study was to compare unimanual training (CIMT) and bimanual training (HABIT) protocols aimed to improve ability of the involved hand in children with hemiplegia.
- Trial name
- CIMT (NCT00619853)
- Testing
- treatment approach - CIMT, treatment approach - HABIT
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Schizophrenia, Family
Family Study in Schizophrenia
Schizophrenia is a severe mental illness which is considered to have, among other, a genetic etiology. One of the most efficient tools in genetic-psychiatry is the investigation of multiplex families.
- Conditions
- Schizophrenia, Family, Genetics
- Trial name
- NCT00418912
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Vascular Diseases
Early Postoperative Fitting of the Air- Limb Prosthesis for Transtibial Amputees
The aim of the study is to check whether an early adjustment of the Air-Limb prosthesis to Transtibial amputees due to vascular diseases, will shorten the healing time of the stump and the process of rehabilitation.
- Trial name
- NCT00616668
- Testing
- Air- Limb
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Pre Operative Anxiety
Clowns as Treatment for Preoperative Anxiety in Children: A Randomized Controlled Trial
This study wants to test the hypothesis that trained clowns can reduce anxiety in children undergoing general anesthesia. We will compare the effect of the clowns to the commonly used anti-anxiety medication we commonly use
- Trial name
- NCT00609960
- Testing
- clowns present, midazolam
- Where
- Israel
- Volunteers
- 65 people
- Sponsor
- Sheba Medical Center
Autism
Autism in Adult Patients and the Effects on Caregivers
Background: The number of adults with autism is expected to rise significantly in the near future, due to two main reasons: First, a dramatic increase in the estimates of the prevalence of autism starting in the mid 1980s…
- Trial name
- NCT00367107
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Depression
Screening Questionnaire for Depression
Depression is common in primary care and general medical settings, but is often unrecognized and untreated by physicians working in those settings.
- Trial name
- NCT00480233
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
OCD
Treatment With Duloxetine for OCD Patients
Testing the efficacy of the SNRI medication Duloxetine for treating OCD patients who did not respond to SSRI
- Trial name
- NCT00399022
- Testing
- Duloxetine
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Major Depressive Disorder
Medical and Psychiatric Co-Morbidity Among Treatment Resistant Patients With Major Depression Disorder
Assessing psychiatric and physiological co-morbidity in TRD and non-TRD patients
- Trial name
- NCT00229398
- Sponsor
- Sheba Medical Center
Obsessive Compulsive Disorder
Short Term Group Therapy for OCD
Assessing OCD before and after group therapy
- Trial name
- NCT00229320
- Testing
- Group therapy
- Where
- Israel
- Sponsor
- Sheba Medical Center
Obsessive Compulsive Disorder
Efficacy of Naltrexone Treatment as Augmentation to SSRI in OCD Patients
Assessing the efficacy of Naltrexone as augmentation to SSRI in patients with OCD
- Trial name
- NCT00234689
- Testing
- Naltrexone
- Where
- Israel
- Sponsor
- Sheba Medical Center
PTSD
Psychological and Physiological Status of Former Prisoners of War
Assessing the psychological and physiological status of Israeli former prisoners of war (POW).
- Trial name
- NCT00294957
- Where
- Israel
- Sponsor
- Sheba Medical Center