Clinical trials: sponsored by Shengjing Hospital
Spinal Cord Tumors
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment
In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.
- Trial name
- NCT05957679
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Chronic Kidney Disease (CKD)
Multifrequency MRE in Evaluation of Chronic Kidney Diseases
Chronic Kidney Disease (CKD) is a major public health issue, leading to high mortality and the necessity for renal replacement therapy.
- Trial name
- NCT06202235
- Testing
- Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Cirrhosis, Liver, Portal Hypertension
3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension
How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis or…
- Conditions
- Cirrhosis, Liver, Portal Hypertension, Advanced Chronic Liver Disease
- Trial name
- NCT05475015
- Testing
- 3D-MRE, HVPG
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shengjing Hospital
Cirrhosis, Liver Portal Hypertension
3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension
How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis.
- Trial name
- NCT06205992
- Testing
- 3D-MRE, HVPG, 2D-MRE
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Meningitis
Neuroendoscopic Surgery With Ommaya Reservoir Implantation vs. Burr Hole Drainage for Infantile Postmeningitis Subdural Lesions: Superior Efficacy, Critical Impact of Surgical Timing, and Pathogenic Bacteria as Risk Factors for Progression
Globally, approximately 750,000 cases of infantile meningitis occur annually[1]. Clinical data show infantile postmeningitis subdural fluid collection (IPSFC) is the most common complication of infantile bacterial meningitis…
- Trial name
- NCT07320599
- Testing
- Endoscopic Subdural Fluid Collection Evacuation & Ommaya Reservoir Implantation
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Glioma
Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we…
- Trial name
- NCT05990244
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Interventional AI-Human Collaboration for Liver Tumor Diagnosis
Recent advances in artificial intelligence (AI), particularly deep learning technology, have transformed medical imaging analysis.
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07153783
- Testing
- AI-human collaboration for CE-CTs diagnosis
- Where
- China
- Volunteers
- 10,333 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
SCI - Spinal Cord Injury, Motor Imagery
Near-Infrared Imaging of Motor Imagery Effects in Spinal Cord Injury
The primary objective of this clinical trial is to investigate the efficacy of motor imagery-based brain-computer interface (MI-BCI) technology in improving motor function among patients with spinal cord injury (SCI), as well as…
- Conditions
- SCI - Spinal Cord Injury, Motor Imagery, Brain-Computer Interfaces
- Trial name
- NCT07106060
- Testing
- EEG-based rehabilitation training device (L-B300), EEG-based rehabilitation training device (L-B300)（Not connected）
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shengjing Hospital
TNBC - Triple-Negative Breast Cancer
A Randomized Study of JS004 and Toripalimab Combined With Chemotherapy vs Toripalimab Combined With Chemotherapy vs Chemotherapy Alone as Neoadjuvant Therapy for Stage II-III Triple-negative Breast Cancer (TNBC).
The objective of this study is to evaluate the efficacy and safety of chemotherapy plus toripalimab, with or without JS004,as neoadjuvant therapy for patients with triple-negative breast cancer (TNBC).
- Trial name
- NCT07101614
- Testing
- JS004 in combination with toripalimab and chemotherapy, Toripalimab and chemotherapy, Chemotherapy
- Volunteers
- 125 people
- Sponsor
- Shengjing Hospital
COPD Patients
The Efficacy and Safety of Arbidol in Reducing the Frequency of AECOPD.
Chronic Obstructive Pulmonary Disease (COPD) is currently the fourth leading cause of death in the world. Acute exacerbations of COPD (AECOPD) are the most important events in the course of the disease because they negatively…
- Trial name
- NCT03851991
- Testing
- Arbidol
- Where
- China
- Volunteers
- 351 people
- Sponsor
- Shengjing Hospital
Spinal Cord Injuries
Effect of Threshold Pressure-Loaded RMT + tTBS on Respiratory Function in SCI Patients
The purpose of this clinical trial is to understand whether threshold pressure load respiratory muscle training combined with iTBS can effectively improve the respiratory function of SCI patients.
- Trial name
- NCT07050069
- Testing
- Transcranial Magnetic Stimulation (TMS) Device / Respiratory Training Device
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shengjing Hospital
Insulin-Like Growth Factor I
Study on Dynamic Changes of Serum IGF-1 Post-Cerebral Hemorrhage and Its Prognostic Correlation
The purpose of this study is to dynamically observe the dynamic changes of serum IGF-1 after intracerebral hemorrhage, explore the impact and correlation of serum IGF-1 with the severity of the patient's condition and prognosis…
- Trial name
- NCT07043504
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Stroke
fNIRS-Driven Visual Feedback Training to Restore Walking After Stroke
The objective of this clinical trial is to investigate whether intelligent visual feedback-based lower limb motor control training is more effective than conventional rehabilitation training in promoting walking ability recovery…
- Trial name
- NCT07014891
- Testing
- Intelligent Visual Feedback Motor Control Training, Bobath Ball Training
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Shengjing Hospital
Metastatic Colorectal Cancer
MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases
The goal of this study is to investigate the value of MR elastography-based SII as a means of detecting HGP noninvasively in patients with pathology-proven CRLM.
- Trial name
- NCT06208397
- Testing
- Magnetic Resonance Elastography and routine MRI
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Liver Stiffness
Multi-parametric Magnetic Resonance Imaging for the Precise Diagnosis and Quantitative Study of Liver Steatosis, Inflammation, and Fibrosis in Chronic Liver Disease.
To construct a novel, non-invasive, accurate, and convenient method to achieve the degree of liver damage is an important general problem in the management of patients with chronic liver disease.
- Trial name
- NCT06463366
- Testing
- 3D-MRE,MRI-PDFF
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Hepatolithiasis, Endoscopy, Digestive System
Evaluation of the Efficacy of the Two-point Method in Percutaneous Transhepatic Choledoscopy and the Influence of the Long-term Recurrence of Hepatolithiasis
The goal of this clinical trial is to evaluate the efficacy and safety of the two-point approach in patients with intrahepatic bile duct stones。The main questions it aims to answer are: ① By comparing the technical success rate…
- Trial name
- NCT06839612
- Testing
- Two-point method, Conventional PTCS
- Volunteers
- 157 people
- Sponsor
- Shengjing Hospital
Polycystic Ovary Syndrome, Chiglitazar
Chiglitazar/Metformin in Non-obese Women With PCOS
Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorders in women of reproductive age, and its prevalence rate is from 9% (NIH criteria) to 18% (Rotterdamcriteria).
- Conditions
- Polycystic Ovary Syndrome, Chiglitazar, Metformin
- Trial name
- NCT06125587
- Testing
- Chiglitazar, Metformin
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Shengjing Hospital
HR Positive/HER2 Low Breast Cancer
SHR-A1811 Alone or in Combination With Adebrelimab as Neoadjuvant Treatment in HR Positive/HER2 Low Breast Cancer
This is an open-label, phase II study evaluating the efficacy and safety of SHR-A1811 alone or in combination with Adebrelimab in Stage II-III HR Positive/HER2 Low Breast Cancer.
- Trial name
- NCT06340230
- Testing
- SHR-A1811 Injection + Adebrelimab Injection, SHR-A1811 Injection
- Where
- China
- Volunteers
- 93 people
- Sponsor
- Shengjing Hospital
Breast Cancer
The Association Between Plasma Metabolites and the Risk, Efficacy and Prognosis in Early Breast Cancer
This study investigates plasma metabolites to clarify the relationship between these metabolites and breast cancer, aiming to identify valuable biomarkers.
- Trial name
- NCT06698679
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Breast Cancer
The Association of Psychological Stress with the Efficacy of Neoadjuvant Therapy in Breast Cancer
This study aims to explore the relationship between psychological stress and the therapeutic response in breast cancer patients who have received standard neoadjuvant chemotherapy.
- Trial name
- NCT06690645
- Testing
- Exposure: psychological stress status
- Where
- China
- Volunteers
- 840 people
- Sponsor
- Shengjing Hospital