Clinical trials: sponsored by Shengjing Hospital
Hyperthyroidism
A Clinical Study of Hyperthyroidism in Children
This study intends to conduct a retrospective and prospective study on children with hyperthyroidism, and it is a non-intervention study to collect information on diagnosis and treatment and long-term follow-up of children with…
- Trial name
- NCT06570967
- Testing
- Methimazole(MMI)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shengjing Hospital
Acute Upper Respiratory Tract Infection, Traditional Chinese Medicine
Clinical Study on the Efficacy and Safety of Qingre Heji in the Treatment of Acute Upper Respiratory Tract Infection
Originating from China, TCM complements conventional approaches by alleviating symptoms, balancing physical conditions, and enhancing immunity. Clinical studies have shown TCM to be safe and effective in treating AURI.
- Conditions
- Acute Upper Respiratory Tract Infection, Traditional Chinese Medicine, Randomised Controlled Trial
- Trial name
- NCT06520618
- Testing
- Qing Re He Ji, Shuanghuanglian Oral Liquid
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Shengjing Hospital
Liver Abscess
A Joint Model Based on Deep Learning to Predict Multidrug-resistant Klebsiella Pneumoniae Liver Abscess
The goal of this observational study is to train a deep learning-based model to predict multidrug-resistant Klebsiella pneumoniae liver abscess and evaluate it on a multi-center database.
- Trial name
- CLASS2401 (NCT06506318)
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Shengjing Hospital
HER2-positive Breast Cancer
A Study of SHR-A1811 Monotherapy or Combined With Pyrotinib Maleate as Neoadjuvant Treatment in HER2-positive Breast Cancer Patients
This is a phase II trial evaluating the efficacy and safety of SHR-A1811 monotherapy or combined with pyrotinib maleate in Stage II-III HER2-positive breast cancer.
- Trial name
- NCT05635487
- Testing
- SHR-A1811, Pyrotinib
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Shengjing Hospital
TACE, HCC - Hepatocellular Carcinoma
Prediction and Prognostic Analysis of Liver Abscess Formation After Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma (CHANCE 2407)
Liver abscess is a rare but serious complication of hepatocellular carcinoma after TACE, with an incidence of less than 1% reported in previous literature.
- Conditions
- TACE, HCC - Hepatocellular Carcinoma, Liver Abscess
- Trial name
- NCT06483594
- Volunteers
- 400 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Clinical Study of High-intensity Focused Ultrasound Tumor Treatment System(Super Knife) in the Treatment of Breast Cancer
Breast cancer is the most common cancer diagnosed among women and is the second leading cause of cancer death among women after lung cancer.
- Trial name
- NCT06210529
- Testing
- a high-intensity focused ultrasound tumor treatment system (Super Knife)
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shengjing Hospital
Triple Negative Breast Cancer
Study of Cadonilimab (AK104) Plus Eribulin vs. Eribulin Monotherapy for Recurrent or Metastatic Triple-negative Breast Cancer
The purpose of this study is to assess the efficacy and safety of Cadonilimab (AK104) plus Eribulin compared to the efficacy and safety of Eribulin monotherapy in the treatment of adult patients with recurrent, or metastatic…
- Trial name
- NCT06202313
- Testing
- Cadonilimab, Eribulin
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Shengjing Hospital
Stereotactic Radiotherapy, Immunotherapy
Stereotactic Radiotherapy Combined With Adebrelimab and TCb (Nab-paclitaxel + Carboplatin) in Neoadjuvant Treatment of TNBC
This study was an open-label, multicenter, randomized study. It is planned to include 136 patients with stage II-III triple negative breast cancer.
- Conditions
- Stereotactic Radiotherapy, Immunotherapy, Breast Cancer
- Trial name
- NCT06165900
- Testing
- adebrelimab plus stereotactic radiotherapy followed by adebrelimab plus chemotherapy (nab-paclitaxel + carboplatin), adebrelimab plus chemotherapy (nab-paclitaxel + carboplatin)
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Breast Cancer Study of Stereotactic Body Radiation Therapy (SBRT) Combined Neoadjuvant Treatment
The study is being conducted to evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT) combined neoadjuvant treatment for patients with triple-negative and hormone receptor-positive, HER2-negative breast…
- Trial name
- NCT05132790
- Testing
- SHR-1316 at a dose 20mg/kg q3w, SHR6390 at a dose of 150mg orally, daily, SBRT
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Shengjing Hospital
Constipation, Childhood ALL
PTNS and PFR in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood, affecting an estimated 20% of children globally. At present, the treatment of children's constipation is full of challenges, and treatment methods are diverse.
- Conditions
- Constipation, Childhood ALL, Pelvic Floor Disorders
- Trial name
- NCT05059756
- Testing
- PTNS
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shengjing Hospital
Fecal Microbiota Transplantation, Constipation - Functional
RCE With FMT in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood gastrointestinal disease, affecting an estimated 20% of the global children.The treatment strategies consist of diet control, behavioral intervention and oral and sometimes…
- Trial name
- NCT05035784
- Testing
- Fecal supernatant
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Constipation, Chinese Herbal Medicine
Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood gastrointestinal disease,affecting an estimated 20% of the global children.The treatment strategies consist of diet control,behavioural intervention and oral and sometimes…
- Trial name
- NCT03186079
- Testing
- Xiaojidaozhi Decoction, Fiberform, Toilet training
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shengjing Hospital
Asthma-COPD Overlap Syndrome, Asthma
The Application of Impulse Oscillometry on the Diagnosis of ACOS,Asthma and COPD.
To Assess the Utility of Impulse Oscillometry on a Differential Diagnosis among the Patients with ACOS,asthma and COPD over Age 40.
- Conditions
- Asthma-COPD Overlap Syndrome, Asthma, COPD, Diagnoses Disease
- Trial name
- NCT03181152
- Testing
- Impulse Oscillometry
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Career Burnout, Student Burnout
A 14-item Questionnaire Regarding Career Preferences Among Chinese Medical Undergraduate Students.
This survey was performed as part of a career choice research program for undergraduate medical students. All students received a QR code link to the survey as part of their course work.
- Trial name
- NCT05531487
- Testing
- Questionnaire Survey
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shengjing Hospital
Group 3 Pulmonary Hypertension
rhBNP in Type 3 Pulmonary Hypertension
Pulmonary hypertension is a common clinical syndrome, which seriously affects the quality of life and survival of patients. Pulmonary hypertension (PH) is defined as an increase in mean pulmonary arterial pressure (mPAP) to ≥20…
- Trial name
- NCT05716984
- Testing
- recombinant human brain natriuretic peptide
- Where
- 2 sites in China
- Volunteers
- 72 people
- Sponsor
- Shengjing Hospital
Recruiting
VTE Risk Prevention System Based on Big Data Analysis and Multimodule System
Venous thromboembolism (VTE) is one of the most common complications in perioperative period and the most common cause of postoperative death. VTE includes deep vein thrombosis (DVT) and acute pulmonary thromboembolism (PTE).
- Trial name
- NCT05969951
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Shengjing Hospital
Fecal Incontinence, Childhood ALL
Management of FI After Surgery of ARM
The posterior sagittal approach to anorectal malformation (ARM) has radically changed the outcome of these patients, improving the preservation of anal sphincters, owing to their anatomical identification.
- Conditions
- Fecal Incontinence, Childhood ALL, Anorectal Malformations
- Trial name
- NCT05621629
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Breast Cancer
Pyrotinib Combined With Trastuzumab, Dalpiciclib, Letrozole Versus TCbHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HR +/HER2 + Breast Cancer
This is an investigator-initiated randomized controlled, open-label, multicenter, prospective Phase 2 clinical study. Patients with stage II-III HR +/HER2 + breast cancer were randomly divided into two groups at a ratio of 1:1.
- Trial name
- NCT05638594
- Testing
- Pyrotinib, Trastuzumab, Dalpiciclib
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Shengjing Hospital
Infertility, Microbiome
Frozen Embryo Transfer Pregnancy Outcomes Prediction by Microbiome and Transcriptome
This study intends to explore the correlation between cervical microbiome, gut microbiome, transcriptome and pregnancy outcomes of frozen embryo transfer patients through a multicenter prospective observational study, and to…
- Trial name
- NCT05545631
- Testing
- no intervention
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
Infertility, Microbiome
Frozen Embryo Transfer Pregnancy Outcomes Prediction by Microbiome
This study intends to explore the correlation between cervical microbiome, gut microbiome and pregnancy outcomes of frozen embryo transfer patients through a multicenter prospective observational study, and to explore the…
- Trial name
- NCT05521295
- Testing
- no intervention
- Where
- China
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital