Clinical trials: sponsored by Shengjing Hospital
Lactation Mastitis
The Effect of Gravity on the Occurrence of Lactational Mastitis
Lactation is the instinct of almost all mammals, including human beings. With the development of human society, the function of lactation has gradually deviated from nature instinct.
- Trial name
- NCT05207241
- Testing
- provides guidance on gravitationally assisted breastfeeding
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Combined Spinal Epidurai Anesthesia, Lower Extremity Surgery
the Relationship Between Vertebral Body Length, Subarachnoid Space Width and Block Level
Spinal anesthesia technology has been widely used in various surgeries and multi-mode analgesia. Spinal ultrasound imaging has been proved to be a reliable tool for evaluating spinal parameters.
- Trial name
- NCT05201261
- Testing
- ltrasonic measure
- Volunteers
- 50 people
- Sponsor
- Shengjing Hospital
Breast Neoplasms
CTC Changes and Efficacy of Neoadjuvant Chemotherapy for Triple-negative Breast Cancer
Chemotherapy before operation for malignant tumors can reduce the size of tumors to a certain extent, even eliminate micrometastases.
- Trial name
- NCT04059003
- Testing
- Taxanes or/and anthracycline-based therapy
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Shengjing Hospital
Twin; Complicating Pregnancy, Psychology
Psychological Screening and Nursing of Twin Pregnancy
Objectives This research will screen the psychological problems of twin pregnant women step by step and detect early and treat early in order to reduce the incidence of mental diseases and promote the health of mother and baby.
- Trial name
- NCT05182541
- Testing
- Guided self help, Problem solving therapy, Face to face PST course
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
HER2-positive Gastric Cancer
Camrelizumab Combined With Chemotherapy in First-line Treatment of HER2-positive Gastric Cancer
According to the investigator's judgment, there are concomitant diseases that seriously endanger the patient's safety, or affect the patient's completion of the study (such as uncontrolled hypertension, diabetes, thyroid disease…
- Trial name
- NCT05070598
- Testing
- Camrelizumab +Pyrotinib + Nab-paclitaxel + Tegafur
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Shengjing Hospital
Sex Differences, Postoperative Sleep Quality
Sex Difference Effects on Postoperative Sleep, Inflammation and Cognition in Patients Undergoing General Anesthesia
Video-Assisted Thoracoscopic Surgery(VATS) is among the most common and disabling persistent pain and inflammation conditions, with increasing prevalence in the developed world, and affects women to a greater degree than men.
- Conditions
- Sex Differences, Postoperative Sleep Quality, Postoperative Pain, Inflammation Function
- Trial name
- NCT05059548
- Testing
- Video-Assisted Thoracoscopic Surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Pathogenic Microorganism of Serious Pneumonia
Pathogenic Microorganisms in Adult Severe Pneumonia Patients
This study aimed to evaluate pathogenic microorganisms in adult severe pneumonia patients in different cities of Liaoning Province
- Trial name
- NCT04433403
- Testing
- pathogenic microorganism
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
Anemia, Iron-Deficiency
Iron Deficiency Anemia in Twin Pregnancies
All pregnant women with twin pregnancies were given oral iron according to the current recommended dose. Blood routine and ferritin were monitored during pregnancy to understand the therapeutic effect of oral iron on iron…
- Trial name
- NCT04975074
- Testing
- Iron
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Breast Cancer
Trastuzumab Combined With Pertuzumab for Adjuvant Treatment of Breast Cancer After Neoadjuvant Therapy
Patients with HER-2 positive breast cancer who have poor outcomes after endocrinotherapy and standard chemotherapy can be significantly improved by the use of anti-HER-2 monoclonal antibody trastuzumab.
- Trial name
- NCT04973319
- Testing
- Pyrotinib, Trastuzumab
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Treatment of Triple-negative Breast Cancer With Albumin-bound Paclitaxel as Neoadjuvant Therapy: a Prospective RCT
Triple-negative breast cancer (TNBC) accounts for about 20% of clinical breast cancer. Clinical characteristics include early onset, high malignancy and heterogeneity.
- Trial name
- NCT04137653
- Testing
- nab-Paclitaxel+carboplatin, Paclitaxel+carboplatin
- Where
- China
- Volunteers
- 1,498 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Sj-subway, a Predictor for the Recurrence of High-risk Hormone Receptor-positive Breast That is Sensitive to Extended Endocrine Therapy
Hormone receptor-positive breast cancer accounts for about 70% of all breast cancers. Extended endocrine therapy with aromatase inhibitor is the current main treatment for hormone receptor-positive breast cancer.
- Trial name
- NCT04476485
- Testing
- endocrine therapy
- Where
- 12 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Albumin-bound Paclitaxel and Carboplatin Versus Epirubicin and Docetaxel for Triple-negative Breast Cancer
To investigate the efficacy of albumin-bound paclitaxel combined with carboplatin versus epirubicin combined with docetaxel as neoadjuvant therapy for triple-negative breast cancer.
- Trial name
- NCT04136782
- Testing
- Albumin-bound paclitaxel combined with carboplatin, Epirubicin combined with docetaxel
- Where
- 7 sites in China
- Volunteers
- 110 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Palbociclib Combined With an Aromatase Inhibitor in Breast Cancer
Pfizer's innovative drug palbociclib (trade name: Ibrance®) got China National Drug Administration (CNDA) approval on July 31, 2018.
- Trial name
- NCT04047758
- Testing
- Palbociclib + Letrozole, Letrozole
- Where
- 3 sites in China
- Volunteers
- 420 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Palbociclib + Letrozole Versus Epirubicin + Cyclophosphamide and Sequential Docetaxel as Neoadjuvant Chemotherapy
With the development of neoadjuvant therapy for tumors, neoadjuvant chemotherapy (NAC) has become one of the most common and effective methods for preoperative systemic treatment of locally advanced breast cancer (LABC).
- Trial name
- NCT04137640
- Testing
- palbociclib combined with letrozole, epirubicin combined with cyclophosphamide and sequential docetaxel
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Study on Bisphosphonates Targeting Triple-negative Breast Cancer
Triple-negative breast cancer has a poor prognosis and lacks effective adjuvant treatment. A number of preclinical and clinical trials have shown that bisphosphonates have direct or indirect anti-tumor activity, and early use of…
- Trial name
- NCT04045522
- Testing
- Zoledronic Acid
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Shengjing Hospital
Twin Diseases
the Prognosis of Fetoscopy Treatment of Twin Transfusion Syndrome
Fetal medicine in China is still a new, young discipline, and the development is very rapid. After nearly 10 years of development, the clinical diagnosis and treatment guidelines of some complicated twin diseases has been…
- Trial name
- NCT04952415
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Morning Inspections, Afternoon Inspections
Comparison of Receiving Painless Gastrointestinal Endoscopy in the Morning or Afternoon on Postoperative Sleep Quality
Gastrointestinal endoscopy (GIE) are important examinations for screening, diagnosing, and treating a variety of gastrointestinal diseases.
- Conditions
- Morning Inspections, Afternoon Inspections, Sleep Quality, Gastrointestinal Endoscopy
- Trial name
- NCT04879771
- Testing
- Receive gastrointestinal endoscopy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Time of First Rehabilitation Therapy
Early Limb Rehabilitation Therapy Within 48 h of Acute Stroke Onset(ERTAS)
This study aimed to evaluate effectiveness of initial limb rehabilitation compare therapy took place within 48h with therapy took place after 48h for patients with stroke (modified Rankin Scale Score 3-4).
- Trial name
- ERTAS (NCT02718534)
- Testing
- stroke rehabilitation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shengjing Hospital
Methylprednisolone, Immunological Function
Effects of Methylprednisolone on Immunological Function and Postoperative Pain
Surgical trauma is characterized by a tightly integrated sequence of neurohumoral and immunological processes. When this is marked, it can manifest as a clinical entity called the systemic inflammatory response syndrome.
- Conditions
- Methylprednisolone, Immunological Function, Postoperative Pain
- Trial name
- NCT03393949
- Testing
- Methylprednisolone 1 mg•kg-1, isotonic saline 1mg•kg-1
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Shengjing Hospital
Transcutaneous Electrical Acupoint Stimulation, Thoracoscopic Surgery
Effect of Transcutaneous Electrical Acupoint Stimulation on Sleep After Thoracoscopic Surgery
General anesthesia is a medically induced state of low reactivity consciousness which is similar to natural sleep.Some studies found that general anesthesia as an independent risk factor could result in a desynchronization of the…
- Conditions
- Transcutaneous Electrical Acupoint Stimulation, Thoracoscopic Surgery, Postoperative Sleep Quality
- Trial name
- NCT04124679
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Shengjing Hospital