Clinical trials: completed, sponsored by Shirley Ryan AbilityLab
Amputation, Amputation; Traumatic, Limb
Low Cost Socket for Lower Limb Amputees
The purpose of this research is to test an investigational fabrication system for transtibial prostheses. This fabrication method will be tested for comfort and function to determine feasibility of use for amputees in developing…
- Conditions
- Amputation, Amputation; Traumatic, Limb, Amputation, Traumatic
- Trial name
- NCT04725461
- Testing
- Low cost lower limb prosthetic socket
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia
Modulating Intensity and Dosage of Aphasia Scripts
The purpose of this study is to evaluate how changing conditions of speech-language treatment (namely, amount of repetition and distribution of practice schedule) affects the language outcome of participants with aphasia…
- Trial name
- MIDAS (NCT04138940)
- Testing
- Script Training
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Shirley Ryan AbilityLab
COVID-19, Healthy Control
Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms
1. Develop a wearable sensor package to gather data on COVID-19-like signs and symptoms such as elevated body temperature, respiratory parameters, heart rate ,cough and gait. 2.
- Trial name
- NCT04393558
- Testing
- ADAM Sensor
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation, Neuropathy
Somatosensation Device Trial
This research is being done to test a new device, called the Somatosensation Device, with people who have either a below knee amputation, or neuropathy (i.e. decreased sensation) in their legs.
- Trial name
- NCT06168396
- Testing
- Somatosensation Device, Baseline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Exercise Therapy, Heart Rate Determination
Assessing Visual Feedback of HR Monitoring in Rehabilitation - Pilot
Monitoring heart rate during exercise can provide feedback to the patient and provider that the patient is exercising in the appropriate, individualized and safe range for them.
- Trial name
- NCT05273801
- Testing
- Heart Rate Recording from Multiple Participants, No Visual Feedback, Visual Feedback of Multiple Participant Heart Rates
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Enhanced Medical Rehabilitation for Spinal Cord Injury
Background: Patient engagement is a cornerstone of patient-centered care. Studies show that an increased level of patient engagement in medical rehabilitation is associated with greater functional recovery.
- Trial name
- EMRSCI (NCT03952416)
- Testing
- Enhanced Medical Rehabilitation (EMR)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Acquired Brain Injury
Rewards Sensitivity After Brain Injury
A study measuring rewards sensitivity in individuals with acquired brain injury at an acute rehabilitation level.
- Trial name
- NCT06510023
- Testing
- Type of reward presented
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Comparison of Two High-intensity Gait Training Interventions on Contraversive Pushing Behaviors in Individuals Poststroke
The purpose of this study is to investigate the effect of two high-intensity gait training interventions on contraversive pushing behaviors in individuals poststroke in the acute inpatient rehabilitation setting.
- Trial name
- NCT04550039
- Testing
- Body-weight-supported treadmill, Ekso Bionics EksoNR exoskeleton
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Acute, Gait Disorders, Neurologic
The Effect of Powered-Knee Exoskeleton Assist on Stair Climbing in Acute CVA
Hypothesis/Specific Aims: The purpose of this research study is to determine if using an exoskeleton during stair climbing training will result in an improved ability to walk and climb stairs in individuals affected by recent…
- Trial name
- NCT03264235
- Testing
- Keeogo, Traditional Stair Training
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Safety and Feasibility of eGlove
The purpose of this study is to measure how cortical signals improve in stroke participants after passive hand stretching therapy from a robotic glove.
- Trial name
- NCT05345301
- Testing
- Event related desynchronization measurement
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia
Improving Electronic Written Communication in Aphasia
People with aphasia have difficulty with writing and often struggle to use electronic communication that connects people to one another.
- Trial name
- T-WRITE (NCT03773419)
- Testing
- Texting Intervention (T-WRITE), HandWriting Intervention (ORLA+WTG)
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Intermittent Hypoxia and Upper Extremity EMG Recordings in Individuals With Spinal Cord Injury
In this current study, the examiners examine some of the mechanisms of how Acute Intermittent Hypoxia (AIH) effects the upper extremity of survivors of spinal cord injury.
- Trial name
- NCT05513911
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia, Stroke
The Intensive Comprehensive Aphasia Program (ICAP)
The purpose of this study is to conduct a randomized clinical trial that assesses the efficacy and cost-effectiveness of an Intensive Comprehensive Aphasia Program (ICAP), specifically focusing on the variable of intensity.
- Trial name
- NCT03514186
- Testing
- Speech and Language Therapy
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Shirley Ryan AbilityLab
Geriatrics
Efficacy of Samsung GEMS-H Device Training in Older Adults
The purpose of this study is to evaluate the feasibility of using Samsung robotic hip assist-based mobility intervention for older adults with frailty.
- Trial name
- NCT05197127
- Testing
- exoskeleton-based gait training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Brain Injuries, Traumatic
Determining the Incidence of Vestibular Dysfunction in Traumatic Brain Injury Patients
The purpose of this study is to determine the incidence of vestibular dysfunction in traumatic brain injury patients admitted to acute inpatient rehabilitation.
- Trial name
- NCT04592575
- Testing
- Vestibular Evaluation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Shirley Ryan AbilityLab
Traumatic Brain Injury, Anxiety
Sleep Quality, Heart Rate Variability and Anxiety Following Brain Injury
The investigators predict that decreased heart rate variability and poor sleep quality will be significantly correlated with higher self-reported anxiety following brain injury.
- Trial name
- NCT04652895
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Shirley Ryan AbilityLab
Speech and Language Disorder, Cerebral Palsy
Effect of mCIMT Casting on Speech-language Outcomes in Children With Hemiparesis
Modified constraint-induced movement therapy (mCIMT) has been successfully used with children who have hemiplegia (weakness or paralysis on one side of the body.) mCIMT uses a removable cast during treatment and home exercise…
- Conditions
- Speech and Language Disorder, Cerebral Palsy, Hemiplegia, Hemiparesis
- Trial name
- NCT04259814
- Testing
- Speech-language therapy (SLT), Modified constraint-induced movement therapy (mCIMT)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Lower Limb Function After Spinal Cord Injury
This is a randomized, experimental study that examines the physiology of central nervous system pathways contributing to the control of bilateral movements in individuals with spinal cord injuries and promotes the recovery of…
- Trial name
- NCT02635893
- Testing
- D-Cycloserine, Training, Stimulation
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Deficit Fields for Stroke Recovery
This study investigates the potential of customized robotic and visual feedback interaction to improve recovery of movements in stroke survivors.
- Trial name
- NCT02570256
- Testing
- Deficit-fields to reduce error, Deficit-fields to expand range of motion, Deficit-fields to improve function
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
In Home VR Therapy
Virtual reality is a video game in which a person and their real-time movements are represented on a screen in a virtual environment.
- Trial name
- NCT03062345
- Testing
- Single-User Virtual Reality Upper Extremity Therapy, Multi-User Virtual Reality Upper Extremity Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab