Clinical trials: completed, sponsored by Shirley Ryan AbilityLab
Hypoesthesia
Multimodal Haptic Feedback for Plantar Sensory Substitution
The study will explore the use of a haptic device for sensory substitution in individuals with a movement disorder that has caused loss of plantar sensation. The haptic device consists of two components.
- Trial name
- NCT06232512
- Testing
- Haptic Device
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
TBI Traumatic Brain Injury
Noninvasive Brain Stimulation to Enhance Cognition at Home Following a TBI.
The purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous vagus nerve stimulation (tVNS) at home, to enhance cognitive recovery in patients with mild-moderate traumatic brain injury…
- Trial name
- NCT07428980
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Shirley Ryan AbilityLab
Traumatic Brain Injury
The Impact of Yoga-based Physical Therapy for Individuals With Traumatic Brain Injury
This study aims to explore if a yoga-based physical therapy session would promote improved (increased) heart rate variability in subjects with traumatic brain injuries.
- Trial name
- NCT03701594
- Testing
- Yoga-based physical therapy group, Seated Rest, Conventional Physical Therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Effects of 4-AP on Functional SCI Recovery
The purpose of this study is to test a strategy to potentiate functional recovery of lower limb motor function in individuals with spinal cord injury (SCI). The FDA approved drug, Dalfampridine (4-AP).
- Trial name
- NCT05447676
- Testing
- Dalfampridine, STDP stimulation, Exercise training
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Real World Upper Extremity Activity of Stroke Survivors
The investigators want to objectively measure, through the use of accelerometers, the time, movement intensity, and bilaterality of Upper Extremity (UE) activity and see if these improve over the course of therapy.
- Trial name
- NCT07557940
- Volunteers
- 15 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Development of Low Cost Devices to Increase Access to Treadmill Training
The goals of this Model System Program are to expand upon and advance the findings and outcomes of previous and current Model Systems clinical research, to continue to develop and study the effectiveness of innovative treatment…
- Trial name
- NCT02560506
- Testing
- Elastic assisted treadmill walking
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
American Heart Association- Stroke/Hypoxia Study
Of the 795,000 people who experience a stroke every year in the US, only a small percentage will achieve full recovery. While current therapies promote strength and endurance, none directly address the unique potential of the…
- Trial name
- NCT04019522
- Testing
- Acute Intermittent Hypoxia (AIH)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Shirley Ryan AbilityLab
Long Covid
Improving Attention in Individuals With Long COVID-19
This study is to find out if the Attention Processing Training program is a potential treatment for brain fog symptoms, reported by people with Long-Covid. Also investigating the feasibility of completing this program virtually.
- Trial name
- LongCovAtten (NCT06503874)
- Testing
- Attention Training, Music Group
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Muscle Spasticity
Altering Activation Patterns Post-stroke
This study evaluates a new rehabilitation approach for stroke survivors in the chronic phase of recovery in which the combination of drug therapy (cyproheptadine) and active movement practice (AMP) is used to encourage increased…
- Conditions
- Stroke, Muscle Spasticity, Hemiparesis
- Trial name
- NCT02418949
- Testing
- Cyproheptadine, Active Movement Practice (AMP), Passive Cyclical Stretching
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Resilience in Persons Following Spinal Cord Injury
This study aims to quantify resilience in survivors of a spinal cord injury. The study will consist of structured interviews and self-reported surveys.
- Trial name
- NCT04544761
- Testing
- Structured Interview
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Weakness, Muscle
EMG Training for Altering Activation Patterns After Stroke
Evaluation of a new EMG controlled game to improve hand function in chronic stroke survivors.
- Conditions
- Stroke, Weakness, Muscle, Coordination Lack
- Trial name
- NCT03619772
- Testing
- Bilateral, Unilateral
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Noninvasive Spinal Stimulation in Stroke
This is a randomized control trial that will evaluate the effectiveness of transcutaneous (non-invasive) spinal cord stimulation on gait and balance function for individuals with hemiplegia due to stroke.
- Trial name
- NCT03714282
- Testing
- Noninvasive spinal stimulation with gait training, Conventional gait training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Corticospinal Function After Spinal Cord Injury
The investigator's overall goal is to develop new strategies to test optimization of Spike-timing-dependent plasticity (STDP) doses to maximize strategy to restore upper and lower-limb motor function in individuals with spinal…
- Trial name
- NCT02451683
- Testing
- Electrophysiology Assessment of Time Domain, Electrophysiology Assessment of Location, Training with some stimulation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Acute
Harmony Scapulohumeral Rhythm (SHR) Reliability and Efficacy Study
The purpose of this study is to assess the safety, reliability, and efficacy of the use of the Harmony Scapulohumeral Rhythm (SHR) upper extremity robotic rehabilitation system for persons with impaired functional use of one or…
- Trial name
- NCT05251077
- Testing
- Harmony SHR, Traditional Occupational Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Shirley Ryan AbilityLab
Brain Injuries, Traumatic
Acute Intermittent Hypoxia in Traumatic Brain Injury
This study is designed to answer questions related to safety and preliminary efficacy of Acute Intermittent Hypoxia (AIH) in Traumatic Brain Injury (TBI) survivors.
- Trial name
- AIH (NCT04890639)
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries, Spinal Cord Diseases
SCI Acute Intermittent Hypoxia and Non-Invasive Spinal Stimulation Combined With Gait Training
This is a single blind, sham controlled crossover trial that will evaluate the effectiveness of acute intermittent hypoxia therapy (AIH) combined with transcutaneous (non-invasive) spinal cord stimulation on gait and balance…
- Trial name
- NCT03922802
- Testing
- Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury
Currently, there are a variety of approaches utilized in attempts to improve upper extremity function, including: traditional therapy, neuroprostheses, botulinum toxin injections, or surgical interventions.
- Trial name
- NCT03643770
- Testing
- Upper extremity training/Armeo Spring
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Acute Stroke
Soft Exosuits for Functional Gait Recovery in Acute Stroke Rehabilitation
The purpose of this study is to develop and evaluate the use of soft exosuits in patients post stroke.
- Trial name
- NCT06231511
- Testing
- Hip flexion soft exosuit, ReWalk ReStore soft exosuit, Conventional physical therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Self-Catheterization Mirror System for Female Patients
The purpose of this study is to test a modified mirror system for female patients to use during self-catheterization.
- Trial name
- NCT05406258
- Testing
- Modified Self-Catheterization Mirror, Standard Self-Catheterization Mirror
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Shirley Ryan AbilityLab
Upper Limb Amputation at the Hand, Upper Limb Amputation at the Wrist
Functional Importance of a Powered Multifunction Wrist Protocol
The focus of this study is to conduct a clinical study in individuals with transradial amputations to compare function using a 1-DOF or 2-DOF wrist.
- Conditions
- Upper Limb Amputation at the Hand, Upper Limb Amputation at the Wrist, Amputation, Amputation; Traumatic, Limb
- Trial name
- NCT04069793
- Testing
- Commercially available device, Non FDA registered device
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Shirley Ryan AbilityLab