Clinical trials: sponsored by Sichuan University
Stage IV NSCLC
Safety and Tolerability Evaluation of Sintilimab in Combination With Radiation in Stage IV NSCLC Patients
This pilot phase I trial aims to investigate the safety and tolerability of anti-programmed cell death-1 (PD-1) monoclonal antibody Sintilimab (also called IBI308) in combination with concurrent stereotactic body radiation…
- Trial name
- NCT03812549
- Testing
- Sintilimab, stereotactic body radiation therapy, Low Dose Radiotherapy
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Sichuan University
Non-squamous Non-small-cell Lung Cancer, Anlotinib
Anlotinib Hydrochloride Combined With AP in Stage IIIB/IIIC/IV Non-squamous Non-small-cell Lung Cancer
Anlotinib is a novel oral multitarget tyrosine kinase inhibitor and primary targeted to VEGFR, FGFR, PDGFR and c-Kit. The ALTER-0303 trial showed that patients with advanced non-small cell lung cancer (NSCLC) who received…
- Trial name
- NCT04012619
- Testing
- Anlotinib Hydrochloride
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Sichuan University
Metastatic Non-small Cell Lung Cancer
PD-1 Knockout Engineered T Cells for Metastatic Non-small Cell Lung Cancer
This study will evaluate the safety of PD-1 knockout engineered T cells in treating metastatic non-small cell lung cancer. Blood samples will also be collected for research purposes.
- Trial name
- NCT02793856
- Testing
- Cyclophosphamide, PD-1 Knockout T Cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Sichuan University
Dental Caries, Oral Bacterial Infection
Ecological Effect of Arginine Dentifrice on Oral Microbiota
caries-free (CF) individuals caries-active (CA) individuals (DMFT ≥ 6) will be recruited. Subjects will be instructed to brush their teeth twice daily for 3 min using Colgate® Sensitive Pro-Relief® toothpaste (containing 8%…
- Conditions
- Dental Caries, Oral Bacterial Infection, Microbiota
- Trial name
- NCT02988349
- Testing
- Colgate® Sensitive Pro-Relief® toothpaste
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Pharyngitis
Effect of Intra-cuff Lidocaine and Tetracaine on Tracheal Tube-induced Emergence Phenomena
It has been proven that tracheal tube inflated with lidocaine could decrease the post-intubation sore throat in nitrous oxide anesthesia.
- Trial name
- NCT00798018
- Testing
- 2% lidocaine, 1% tetracaine, N.S
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sichuan University