Clinical trials: sponsored by Sohag University
Seizures
Electrocardiographic Changes Among Epileptic and Non Epileptic Seizures in Children at Sohag University Hospital
Epilepsy is a chronic disease triggered by increased impulsiveness of nerve cells in the brain and may require a lifelong treatment. Epilepsy is confirmed by two or more unprovoked seizures in more than 24 hours.
- Trial name
- NCT06045676
- Testing
- ECG
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Sohag University
Upper and Lower Gastrointestinal Bleeding
Clinical and Endoscopic Pattern in Children Presented With Upper and Lower Gastrointestinal Bleeding Insohag University Hospital
Gastrointestinal bleeding (GIB) is one of the most common conditions in the emergency department. Upper GIB is a major problem that has been decreasing over the past 20 years but still has high mortality rate.
- Trial name
- NCT06047873
- Testing
- Endoscopy
- Volunteers
- 30 people
- Sponsor
- Sohag University
Auditory Neuropathy Spectrum Disorder,, Peripheral Neuropathy
Prevalence of Peripheral Neuropathy Among Patients With Auditory Neuropathy
Auditory neuropathy/ dys-synchrony/ peri-synaptic audiopathy (AN) are terms used to describe a specific hearing disorder with a disturbed auditory neural response in presence of normal cochlear function.
- Trial name
- NCT06041360
- Testing
- Pure tone audiometry PTA ,Speech audiometry ,Otoacoustic emission,Auditory evoked potentials including (ABR).
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Post Operative Pain
Ketamine and Dexmedetomidine Comparative Study
In this study, the investigators will compare the effect of adding ketamine and dexmedetomidine to bupivacaine in US-guided combined sciatic and femoral nerve blocks as regards the onset and duration of the block, postoperative…
- Trial name
- NCT06032624
- Testing
- combined ultra-sound guided femoral and sciatic nerve block.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Post-operative Pain
The Pectoralis (PECS2) Block Versus Intrathecal Morphine
50 patients with American Society of Anesthesiologists (ASA) grade I to II, 18 to 60 years of age scheduled for Modified Radical Mastectomy surgery, Will be included in the study.
- Trial name
- NCT06016205
- Testing
- intrathecal morphine injection, ultrasound guided PECS2 block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Effect of Vitamin A and Calcium in Patients With Non-alcoholic Fatty Liver Patients
Effect of Vitamin A and Calcium in Patients With Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) has become the most common liver disease at a global scale and is strongly associated with the obesity and metabolic syndrome .
- Trial name
- NCT06031532
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hepatitis B, Chronic
Study IL- 35 Level and Fibronectin Type Ⅲ Domain Containing Protein 5 \ Irsin (FNDC5 rs3480) Gene Variations in Chronic Hepatitis B.
Find a possible association between Fibronectin type Ⅲ domain containing protein 5 \ Irsin (FNDC5 rs3480) gene single nucleotide polymorphism with chronic hepatitis B and the distribution of its alleles, in relation to many…
- Trial name
- NCT06023745
- Testing
- genotyping
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Autoimmune Hepatitis
Pattern of Autoimmune Hepatitis in Children In Sohag University Hospital
Autoimmune hepatitis (AIH) is a progressive inflammatory liver disorder of unknown etiology. If left untreated, it progresses to liver cirrhosis and liver failure.
- Trial name
- NCT06020976
- Testing
- liver biobsy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Ankylosing Spondylitis
Platelet and Red Blood Cell Volume Indices as Inflammatory Biomarkers in Ankylosing Spondylitis
this study aims to determine the relatioships among the NLR ,PLR ,MLR ,red cell volume and platelet volume indices levels as biomarkers in ankylosing spondylitis.
- Trial name
- NCT05997108
- Testing
- CBC
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sohag University
Multiple Myeloma
Cyclin D1 as a Prognostic Factor in Multiple Myeloma and Its Association With the Immunological Prognostic Factor PDL1 and Clinical and Biochemical Lab Tests
Multiple myeloma (MM) is the most common bone marrow malignancy of terminally differentiated plasma cells. It accounts for about 1% of all malignant diseases and 10% of haematological malignancies and takes the second place after…
- Trial name
- NCT05995808
- Testing
- Bone marow biopsy and aspiration, biochemical and heamatological tests
- Volunteers
- 30 people
- Sponsor
- Sohag University
Polycythemia Vera
Hematocrit to Hemoglobin Ratio and Red Blood Cell Distribution Width in Polycythemia Vera and Secondary Erythrocytosis.
Polycythemia vera (PV), a hematological neoplasm characterized by excessive erythropoiesis due to Janus kinase 2 (JAK2)- activating mutations.
- Trial name
- NCT05993065
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Myeloproliferative Neoplasm
Carotid Plaque Burden in Patients With Philadelphia Negative Myeloproliferative Neoplasms
In around 90% of the patients with MPNs, an acquired mutation that promotes JAK/STAT signaling is identified [3, 4]. The JAK/STAT pathway transduces signals from cytokines including erythropoietin, thrombopoietin, and granulocyte…
- Trial name
- NCT05993052
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Chronic Spontaneous Urticaria
Assessment of Serum Levels of Adenosine Deaminase and Immunoglobulin E in Patients With Chronic Spontaneous Urticaria
adenosine deaminase activity (ADA) has been reported to be elevated in various diseases such as psoriasis, acne and juvenile idiopathic arthritis.
- Trial name
- NCT05992987
- Testing
- Adenosine deaminase serum level, IgE antibodies serum level
- Volunteers
- 90 people
- Sponsor
- Sohag University
Non-segmental Vitiligo
ASSESSMENT OF TRISTETRAPROLIN EXPRESSION IN LESIONAL SKIN OF PATIENTS WITH NON SEGMENTAL VITILIGO
Vitiligo is characterized by the selective loss of melanocytes, which in turn leads to totally amelanotic, non-scaly, chalky-white macule with distinct margins Vitiligo is the most common depigmenting skin disorder, with an…
- Trial name
- NCT05990309
- Testing
- skin biopsy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Neonatal Sepsis
Role of Neutrophil CD64 and Monocyte HLA-DR Markers in the Dignosis of Neonatal Sepsis
Neonatal septicemia remains one of the main causes of neonatal morbidity and mortality . Sepsis which is caused by a dysregulated host response to an infectious trigger leading to a life threatening organ dysfunction was declared…
- Trial name
- NCT05985174
- Testing
- CD64 , HLA-DR
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Multiple Fractures of Ribs
Outcome of Surgical Fixation of Multiple Fractured Ribs at Sohag University Hospital
The ribs are rigid and flexible structures that make up the chest skeleton and are a set of twelve paired bones. After Blunt trauma rib fractures incidence is about 30 to 40% [1].
- Trial name
- NCT05975762
- Testing
- surgical rib fixation
- Volunteers
- 60 people
- Sponsor
- Sohag University
Patients With Atrial Fibrillation Receiving Oral Anticoagulants
"ORBIT" Versus "HAS-BLED" Scores in Predicting Major Bleeding in Patients With Atrial Fibrillation Receiving Oral Anticoagulants.
Atrial fibrillation (AF) is type of arrhythmia characterized by an irregular and often rapid heartbeats, it has strong associations with other cardiovascular diseases, such as heart failure, coronary artery disease (CAD)…
- Trial name
- NCT05975320
- Testing
- Warfarin
- Volunteers
- 100 people
- Sponsor
- Sohag University
Post Operative Sore Throat
Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study
Sore throat includes specific symptoms such as dysphagia, dysphonia, hoarseness, continuous throat pain, and pharyngeal dryness.
- Trial name
- NCT05975346
- Testing
- Ketamine, saline nebulization
- Volunteers
- 80 people
- Sponsor
- Sohag University
Multiple Fracture Ribs
Prospective Comparative Study Between Ultrasound-guided Continuous Erector Spinae Plane Block and the Use of Intravenous Patient Controlled Analgesia for Management of Pain in Patients With Multiple Fracture Ribs
Rib fractures are common after blunt injury to the chest. Present in 10% of blunt trauma admissions. Pain associated with rib fractures can result in compromise of pulmonary function causing hypoxaemia or pneumonia, which may…
- Trial name
- NCT05975294
- Testing
- amixture 0.125% bupivicaine with fentanyl, 100 ml volume containing 80 mg of nalbuphine ,180 mg ketorolac, 24mg dexamethasone, 16 mg danset
- Volunteers
- 60 people
- Sponsor
- Sohag University
Hepatocellular Carcinoma
Predictors of Sorafenib Response in HCC
Evaluating the nutrition status of patients with advanced HCC who received sorafenib. Using the pretreatment nutrition status and quality of life as predictors to sorafenib response
- Trial name
- NCT05967429
- Testing
- The neutrophil-to- lymphocyte ratio, Prognostic nutrition index
- Volunteers
- 80 people
- Sponsor
- Sohag University
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