Clinical trials: sponsored by Sohag University
SOFT TISSUE DEFECTS
Outcomes and Clinical Applications of Thin Free Flaps for Soft Tissue Defects
Flap coverage is often required to achieve primary wound closure and to achieve a good functional result. Free flap has gain popularity over random flap in soft tissue reconstruction to achive maximal cosmetic and functional…
- Trial name
- NCT05828771
- Testing
- THIN FREE FLAP
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Sohag University
Evaluate Laparoscopic Management in Patients With Penetrating Anterior Abdominal Wall Trauma
Role of Laparoscopy in Penetrating Anterior Abdominal Wall Injuries
The current study is aiming to evaluate the diagnostic and therapeutic role of laparoscopy in patients with penetrating anterior abdominal wall trauma as regard the accuracy of diagnosis and efficacy in management and avoidance…
- Trial name
- NCT05826262
- Testing
- diagnostic laparoscopy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Heart Failure With Preserved Ejection Fraction, Non Alcoholic Fatty Liver
Relationship Between Heart Failure With Preserved Ejection Fraction and Nonalcoholic Fatty Liver Disease.
The aim of our study to determine the demography, relation between patients with heart failure with preserved ejection fraction and those with nonalcoholic fatty liver disease in Sohag university hospital.
- Trial name
- NCT05822622
- Testing
- echocardiography
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Isolation of Enterococci From Samples, Demonstration of Enterococci Antibiotic Susceptibility
Phenotypic and Genotypic Variations of Enterococcus Spp
Enterococci are Gram-positive facultative anaerobic cocci arranged in short and medium chains. Enterococci reside in the gastrointestinal tract and usually function commensally with humans.
- Conditions
- Isolation of Enterococci From Samples, Demonstration of Enterococci Antibiotic Susceptibility, Detection of Strains Enterococci Produce Biofilm, Studying Effect of Nanoparticles on Enterococci Antimicrobial Resistance
- Trial name
- NCT05751317
- Testing
- Culture, Staining:, Biochemical reactions:
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
All Patients With Upper GIT Symptoms and Underwent Upper Endoscopy
Pattern Of Endoscopic Findings In Patients Underwent Upper Endoscopy In Sohag University Hospital
Diseases associated with upper gastrointestinal tract (UGIT) are common and associated with significant morbidity and mortality globally.
- Trial name
- NCT05820061
- Testing
- upper endoscopy
- Where
- Egypt
- Volunteers
- 800 people
- Sponsor
- Sohag University
Fracture Fixation, Intramedullary, Fracture Forearm
Percutaneous Intramedullary K-wires Fixation of Pediatric Shaft Both Bone Forearm Fractures
This study is to improving outcome of pediatric both bone forearm fractures using minimally invasive procedure by intramedullary K-wires.
- Trial name
- NCT05744349
- Testing
- K-wires Fixation of Pediatric Shaft Both Bone Forearm Fractures
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Autism Spectrum Disorder
Evaluation of Serum Adrenal Androgens Among Prepubertal and Pubertal Boys With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder of unclear etiology. There are theories depicting the importance of sex steroid hormones in autism, since the prevalence of the disorder is male-biased.
- Trial name
- NCT05811507
- Testing
- serum total testosterone, serum androsterone, serum androstenedione and serum dehydroepiandrosterone sulfate, The Childhood Autism Rating Scale (CARS), DSM-5 Diagnostic Criteria for ASD
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Corneal Topography
Comparison Between Bare Scleral Technique and Conjunctival Auto-graft on Corneal Topography After Pterygium Surgery
Aim of the work: To study the corneal topographic pattern changes in patients who have pterygium excision by two surgical techniques (bare sclera, conjunctival autograft).
- Trial name
- NCT05812508
- Testing
- corneal topography
- Volunteers
- 30 people
- Sponsor
- Sohag University
Negative-Pressure Wound Therapy, Diabetic Foot
Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds
The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.
- Trial name
- NCT05716503
- Testing
- Negative Pressure Wound Therapy (NPWT), Ordinary dressings with antibiotic ointment and gauze
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Temporomandibular Joint Disc Displacement, Without Reduction
Outcomes of Surgical Management of Temporomandibular Joint Anterior Disc Displacement Without Reduction
this study will be done to detect the best management of temporo-mandibular joint anterior disc displacement without reduction, for diagnosis, we use MRI on the TMJ to detect status of the disc and joint space, for management, we…
- Trial name
- NCT05478915
- Testing
- discectomy of the TMJ disc, TMJ discopexy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Hepatic Steatosis and Fibrosis in Rheumatoid Arthritis Patients
Hepatic Steatosis and Fibrosis in Rheumatoid Arthritis Patients
studying the prevalence of hepatic steatosis and fibrosis in a large scale of patients with RA and healthy controls
- Trial name
- NCT05679648
- Testing
- ultrasonography
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pseudomonas Aeruginosa
Molecular Detection Of Efflux Pump and Virulence Factors Genes in Pseudomonas Aeruginosa
Pseudomonas aeruginosa (PA) is a ubiquitous aerobic, non-fermentative Gram-negative rod that is widely associated with nosocomial pneumonia and can lead to severe illness with poor outcomes, particularly in critically ill people…
- Trial name
- Pseudomonas (NCT05642767)
- Testing
- culture on cetrimide agar, Staining with Gram stain, Antibiotic sensitivity testing
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Sohag University
Primary Immune Thrombocytopenia
Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP)
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by low platelet counts with or without mucocutaneous bleeding (McMillan, 2007).
- Trial name
- microRNAITP (NCT05371743)
- Testing
- Plasma RNA isolation, qPCR analysis of micro RNA, estimation of serum level of IL2, estimation of serum level of IL17
- Where
- Egypt
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Sohag University
Lung Ultrasound, Spirometry
Transthoracic Ultrasonography Findings and Their Relation to Spirometric Indices in Patients With Obstructive and Restrictive Respiratory Diseases
Evaluation of respiratory function is considered a crucial component in the assessment of patients with a wide range of respiratory diseases. Spirometry is considered a common method of measuring pulmonary function.
- Conditions
- Lung Ultrasound, Spirometry, Respiratory Diseases, Diaphragm Ultrasound
- Trial name
- NCT05175313
- Testing
- transthoracic ultrasonography, spirometry
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Detection of Type VI Secretion System in K.Pneumoniae, Detection of Relation to Ab Resistance, Biofilm
Type VI Secretion System in Klebsiella Pneumoniae
Klebsiella pneumoniae (K. pneumoniae) is an important opportunistic pathogen contributing to nosocomial and antimicrobial-resistant infections. The increasing prevalence of infections caused by multidrug-resistant K.
- Trial name
- Klebsiella (NCT05516654)
- Testing
- Routine bacteriological cultures, Identification of the organism and antibiotic sensitivity will be done by VITEK II, Detection of biofilm formation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sohag University
Acute Leukemia
Study of miRNA-155 in Acute Leukemia
The leukaemias are a heterogeneous group of blood cancers, Acute leukaemia (AL) is caused by malignant proliferation of blood cells arrested at an immature stage of development, They are very aggressive diseases that run a…
- Trial name
- NCT05809050
- Testing
- BM aspirate
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Aberration, Corneal Wavefront
Correlation of Angle Kappa , Corneal High Order Aberrations and Total Eye Aberrations in Various Refractive Errors
Identification of the correlation between angle kappa , corneal high order aberrations and total eye aberrations in myopic hyperopic and astigmatic patients
- Trial name
- NCT05741190
- Testing
- Pentacam Imaging
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hepatocellular Carcinoma
Role of DEB-TACE Versus c-TACE in Treatment of HCC
Hepatocellular carcinoma (HCC) is listed as the sixth most common cancer worldwide and the third most frequent cause of cancer-related mortality. The majority of HCC cases occurs stem from chronic liver disease and cirrhosis.
- Trial name
- NCT05093920
- Testing
- Doxorubicin-Eluting Beads
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Thrombocytopenia
Assessment of FOXP3 Gene Polymorphisms and Serum Interleukin 10 in Patients With ITP
Immune thrombocytopenia (ITP) is an autoimmune condition characterized by increased platelet destruction and suppression of production resulting in isolated thrombocytopenia.
- Trial name
- FoxP3ITP (NCT05410249)
- Testing
- Serum IL10 By ELISA, SNP -3279 A/C of FOXP3, SNP-924 A/G Of FOXP3
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cancer of Colon
Significance of Immunohistochemical Expression of Fascin-1 in Colorectal Carcinoma
Colorectal carcinoma is a major health problem. As a malignant tumor, the malignant potential of colorectal carcinoma is based mainly on its ability to metastasis to different sites.
- Trial name
- NCT05553080
- Testing
- Immunohistochemistry
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
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