Clinical trials: sponsored by Sohag University
Emergence Agitation
Dexmedetomidine vs Propofol-lidocaine Mixture in Preventing the Post Operative Emergence Agitation Following Sevoflurane Anasthesia
Primary we will Compare the Efficacy between Dexmedetomidine and "Propofol-lidocaine" mixture in preventing the post operative emergence agitation following sevoflurane anasthesia in pediatric ophthalmic surgeries Secondary we…
- Trial name
- NCT07601698
- Testing
- Dexmedetomidine, Propofol
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Laparoscopic Cholecystectomy Surgery Postoperative Analgesia
RLB vs ERSP for Postoperative Analgesia in Lap Cholecystectomy
This prospective, randomized, double-blind clinical trial evaluates the comparative effectiveness of ultrasound-guided retrolaminar block (RLB) and erector spinae plane block (ESPB) for postoperative analgesia in patients…
- Trial name
- NCT07598162
- Testing
- Retrolaminar Block (RLB), Erector spinae plane block (ESPB)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Rheumatoid Arthritis Disease Flare
Prognostic Factors and Predictors of Disease Flare in Patients With Rheumatoid Arthritis
The goal of this observational study is to help find better ways to predict when a flare of your disease (rheumatoid arthritis) might happen.
- Trial name
- NCT07381296
- Testing
- Clinical and Laboratory Monitoring for RA Disease Flare
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Chronic Obstructive Pulmonary Disease (COPD), Mechanical Ventilator Weaning
D-RSBI Versus RSBI for Predicting Weaning Success in COPD Patients
This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success…
- Trial name
- NCT07590362
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Sarcopenia, ESRD (End Stage Renal Disease)
Serum Insulin-like Growth Factor-1 to Albumin Ratio as a Biomarker for Sarcopenia Severity in End-Stage Renal Disease Patients on Hemodialysis
Sarcopenia is a prevalent and serious complication among patients with End-Stage Renal Disease (ESRD) receiving maintenance dialysis, characterized by progressive loss of skeletal muscle mass, strength, and physical function.
- Trial name
- NCT07586956
- Volunteers
- 110 people
- Sponsor
- Sohag University
Regional Block for Postoperative Analgesia in Cesarean Section
Comparison Between Erector Spinae Plane Block vs Transversus Abdominis Plane Block for Postoperative Analgesia in Cesarean Section
This study is a prospective randomized controlled trial designed to compare the effectiveness of the erector spinae plane (ESP) block versus the transversus abdominis plane (TAP) block for postoperative analgesia in patients…
- Trial name
- NCT07582640
- Testing
- Erector Spinae Plane Block For Postoperative Analgesia In Cesarean Section, Transversus Abdominis Plane Block For Postoperative Analgesia In Cesarean Section
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Adenotonsillar Hypertrophy
Intranasal Midazolam for Preanasthetic Sedation for Preschool Children Undergoing Adenotonsillectomy.
This study aims to evaluate the effectiveness of Intranasal Midazolam as preanasthetic sedation for preschool children (2-6)y undergoing adenotonsillectomy.
- Trial name
- NCT07045597
- Testing
- intranasal normal saline for preanasthetic sedation for Adenotonsillectomy, intranasal midazolam for preanasthetic sedation for Adenotonsillectomy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Systemic Lupus Erythematosus Disease
AGR+PNI as Predictors of Systemic Lupus Erythematosus Disease Activity
This study aims to evaluate the clinical utility of combining the albumin to globulin ratio (AGR) and the prognostic nutritional index (PNI) as a predictive model for assessing disease activity in patients with systemic lupus…
- Trial name
- NCT07043153
- Testing
- Albumin to globulin ratio and prognostic nutritional index model
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Rheumatoid Arthritis
Nerve Conduction Study for Assessment of Peripheral Neuropathy in Rheumatoid Arthritis Patients on the Janus Kinase Inhibitor Baricitinib
Rheumatoid arthritis is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues.
- Trial name
- NCT06977035
- Testing
- Nerve Conduction Study
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Shock
Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors
This study aims to evaluate the effectiveness of midodrine as an adjuvant to norepinephrine in weaning critically ill patients from vasopressors
- Trial name
- NCT06930235
- Testing
- Weaning critically ill patients from norepinephrine using midodrine as an adjuvant to norepinephrine, Weaning critically ill patients from norepinephrine without use of midodrine as an adjuvant
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Sohag University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Acute Coronary Syndromes (ACS)
MPV as a Predictor for ACS in Patients With MASLD
The aim of this study is to evaluate mean platelet volume (MPV) as a predictor of acute coronary syndrome (ACS) in patients with metabolic dysfunction-associated steatotic liver disease (MASLD to evaluate mean platelet volume…
- Trial name
- MPV/ACS MASLD (NCT07487571)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Open Heart Surgery
Dose for Reversal of Heparin After Cardiopulmonary Bypass
Protamine sulfate is routinely used to reverse heparin anticoagulation after cardiopulmonary bypass (CPB). The conventional dosing strategy of 1 mg protamine per 100 IU of heparin may result in excess protamine exposure, which…
- Trial name
- NCT07477977
- Testing
- Protamine sulfate
- Where
- Egypt
- Volunteers
- 195 people
- Sponsor
- Sohag University
Assessment of Some Hormone Levels in Children With Dilated Cardiomyopathy
Endocrinal Dysfunction Among Children With Dilated Cardiomyopathy
All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet). 1. Clinical History: focusing on: Socio-demographic factors, especially age, gender, family history, and degree of…
- Trial name
- NCT07567417
- Testing
- Echocardiography assessment., Laboratory investigations and Hormone assessment.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Acute Pulmonary Embolism
Clinical Scores, Biomarkers, and CT Findings in Acute Pulmonary Embolism
This study aims to compare clinical scoring systems, laboratory biomarkers, and computed tomography (CT) findings in patients diagnosed with acute pulmonary embolism in different hospital departments.
- Trial name
- PEST (NCT07566858)
- Testing
- No Intervention (Observational Study Data Collection)
- Volunteers
- 50 people
- Sponsor
- Sohag University
Prediabetic State (IGT), Prediabetic State
Intestinal Endotoxemia and Beta- Cell Dysfunction in Prediabetics
the goal of this observation study is to learn about association between intestinal endotoxemia and prediabetes lean patients with the aim of prevention of diabetes in those category of patients
- Trial name
- NCT07557329
- Testing
- hba1c, lbp, fasting blood sugar, lipogram, fastinf insulin
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sohag University
Obstructive Jaundice, ERCP
Determinants of Technical Success and Safety in Therapeutic ERCP for Obstructive Jaundice
compare the impact of type of anesthesia on ERCP including technical success, rate of complications, peri procedural safety, patient and endoscopist satisfaction in adult patients with obstructive jaundice
- Conditions
- Obstructive Jaundice, ERCP, Anesthesia Complication, Anesthesia Effectiveness
- Trial name
- ERCP (NCT07563569)
- Testing
- ERCP
- Volunteers
- 100 people
- Sponsor
- Sohag University
Pediatric Immune Mediated Interstitial Lung Disease
Diagnostic and Prognostic Utility of IL-6 and MMP-7 in Pediatric Immune Mediated Interstitial Lung Disease
Pediatric interstitial lung disease (ILD) represents a heterogeneous group of rare but potentially severe pulmonary disorders characterized by diffuse parenchymal involvement and impaired gas exchange.
- Trial name
- NCT07559435
- Testing
- IL-6 (interlukin 6), High-Resolution Computed Tomography (HRCT):, Pulmonary Function Tests (PFTs)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Vitiligo - Macular Depigmentation
Comparative Study of Microneedling With Topical Minoxidil 5% ± NB-UVB in Stable Vitiligo"
This study is a randomized controlled trial comparing microneedling with topical minoxidil 5% versus microneedling with minoxidil combined with NB-UVB phototherapy in stable vitiligo.
- Trial name
- NCT07548918
- Testing
- microneedling with minoxidil 5% and NBUVB, Microneedling with Minoxidil5%
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Rectal Cancer Patients, Total Neoadjuvant Therapy
Nodal Downstaging Versus Primary Tumor Regression as Predictors of Survival After Total Neoadjuvant Therapy for Rectal Cancer: A Retrospective Study
To evaluate the prognostic impact of post-TNT pathological nodal status (ypN) on LRFS, DMFS, and OS, and compare it with that of primary tumor response
- Trial name
- NCT07557316
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Age-related Cataract
Chronological Versus Non-chronological Phacoemulsification Training
The goal of this clinical trial is to compare between two methods used in training residents on phacoemulsification. The residents were classified into two groups; the first group were trained on surgical steps in a chronological…
- Trial name
- NCT07337070
- Testing
- Chronological phacoemulsification training, Non-Chronological phacoemulsification training
- Where
- Egypt
- Volunteers
- 800 people
- Sponsor
- Sohag University
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