Clinical trials: sponsored by Stanford University
Medulloblastoma, Central Nervous System Embryonal Tumor
GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults
This is a single-site, open-label Phase I treatment study evaluating the manufacturing feasibility and safety of chimeric antigen receptor (CAR) T cells targeting the oncofetal protein Glypican-2 (GPC2) in pediatric and young…
- Conditions
- Medulloblastoma, Central Nervous System Embryonal Tumor, Refractory Medulloblastoma, Recurrent Medulloblastoma
- Trial name
- NCT07087002
- Testing
- GPC2-CAR T cells, Fludarabine, Cyclophosphamide
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Stanford University
Optic Neuropathy, Glaucoma
Hyperbaric Oxygen Therapy for Optic Neuropathies
The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.
- Trial name
- HBOT (NCT06128720)
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Type1diabetes
Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Pediatric T1D - 4T Study
The 4T program encompasses: Teamwork, Targets, Technology, and Tight Range. These methods will help patients better manage their condition of Type 1 Diabetes with improved patient-reported outcomes.
- Trial name
- NCT04336969
- Testing
- 4T Education and Care
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Stanford University
Pain, Anxiety
Examining Bluetooth Haptic Device Use for Pain and Distress Reduction in Vascular Access Procedures
This pragmatic, randomized study seeks to evaluate the applications of a novel vibrating device for reducing pediatric anxiety and distress during vascular access procedures.
- Trial name
- VA+BHD (NCT06234228)
- Testing
- Bluetooth Haptic Device (BHD), BHD synced with mobile game
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Stanford University
Air Pollution Exposure
Voices Illuminating Solutions for Outdoor Workers' Needs and Safety
The goal for this multidisciplinary randomized controlled trial (RCT) is to actively and meaningfully engage outdoor workers (can include agricultural workers, construction workers, landscaping, wildland firefighters, fire…
- Trial name
- VISIONS (NCT07713264)
- Testing
- Receive education on heat and air quality health risks, Participate in Photovoice and climate health risk education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Lung Cancer
Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer
The purpose of this study is to examine the use of hypofractionated accelerated radiation therapy (HART) to treat locally advanced lung cancer. Depending on the location and size of the tumor.
- Trial name
- NCT06080061
- Testing
- Hypofractionated accelerated radiation therapy
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Parkinson Disease
Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait Using Neural and Kinematic Feedback
Deep Brain Stimulation of the subthalamic nucleus (STN) has become a standard of care, FDA-approved treatment for Parkinson's disease, with stimulation delivered at a constant amplitude and voltage, operating in an open-loop…
- Trial name
- NCT04043403
- Testing
- Open Loop DBS, Adaptive (Closed Loop) DBS, Intermittent Open Loop DBS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Ductal Breast Carcinoma in Situ
Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma
The purpose of this pilot study is to compare by pathological findings surgical excision versus neoadjuvant radiotherapy followed by delayed surgical excision of ductal carcinoma in situ (DCIS)
- Trial name
- NORDIS (NCT03909282)
- Testing
- Lumpectomy, Partial breast irradiation prior to surgery
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Liver Failure
TLI- and ATG-Enabled Minimization Protocol in Liver Transplantation
The unmet medical need in solid organ transplantation is to eliminate the lifelong requirement of powerful immune suppression drug combinations with their attendant side effects, and to prevent immune mediated rejection of the…
- Trial name
- TEMPO-LT (NCT07634562)
- Testing
- Anti-Thymocyte Globulin, ATG (Rabbit), Total lymphoid irradiation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Virtual Reality
The WOW Project (WOW): Wonders Of The World Through Virtual Reality for Hospitalized Children
Hospitalized pediatric patients are unable to leave the hospital to engage in traditional learning environments. Patients often feel depressed, disconnected from learning, and socially withdrawn.
- Trial name
- WOW (NCT06911996)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Stanford University
Lymphoblastic Leukemia
Study of Brexucabtagene Autoleucel Plus Dasatinib in Adults With Acute Lymphoblastic Leukemia
To assess the feasibility of oral dasatinib pulses (3 consecutive days per week) during the first month following infusion of brexucabtagene autoleucel (Tecartus) in adults with relapsed or refractory B-cell acute lymphoblastic…
- Trial name
- NCT05993949
- Testing
- Dasatinib
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Chronic Pain, Cesarean Section Complications
Empowered Relief: A One-Time Session to Help Postpartum Women Manage Ongoing Pain After Cesarean Delivery
The purpose of this study is to study the effect of a pain relief skills session (Empowered Relief) on chronic pain incidence at 12 weeks post cesarean delivery.
- Trial name
- NCT07090018
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Cancer
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
A research study on the diagnosis of spread of disease for children who have been diagnosed with solid tumors using a new whole body imaging technique and a new MR contrast agent (ferumoxytol).
- Trial name
- NCT01542879
- Testing
- WB-DW-MR scan, 18-F-FDG PET scan, Ferumoxytol
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Stanford University
Alzheimer s Disease, MCI With Increased Risk for Alzheimer Disease
Ultrasonic Debris Clearance to Promote Brain Resilience
This pilot study will evaluate the safety, tolerability, and feasibility of Ultrasonic Debris Clearance (UDC), a noninvasive low-intensity focused ultrasound intervention, in amyloid-positive adults who are asymptomatic but at…
- Trial name
- NCT07573982
- Testing
- Ultrasonic Debris Clearance
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Mental Health Services, Community Mental Health Services
MHE3 Clinical Trial - Overcoming Obstacles
The goal of this clinical trial is to increase and strengthen connections between Latino/a individuals and mental health services.
- Conditions
- Mental Health Services, Community Mental Health Services, Community Health Services, Preventive Health Services
- Trial name
- NCT06712147
- Testing
- Overcoming Life's Hurdles: Mental health education, Overcoming Life's Hurdles: Resources in the community
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colorectal Cancer
Advocacy, Partnership, Outreach, and Yielding Optimized Care for Oncology Patients
This study is a pilot feasibility randomized trial involving newly diagnosed colorectal cancer (CRC) patients who identify as Latinx.
- Trial name
- NCT07403981
- Testing
- CHW/P Navigator Support, Social Services Resource List
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Diabetes Type 1
Insul-In This Together: Leveraging Family Support and Diabetes Technology for Adolescents Living With Type 1 Diabetes
The goal of this clinical trial is to learn if the "Insul-In This Together" family program works to improve outcomes for adolescents living with type 1 diabetes.
- Trial name
- IITT (NCT07856836)
- Testing
- Insul-In This Together
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Cutaneous Leishmaniasis, Pain
Immersive Technology Headsets to Reduce Procedural Pain and Anxiety: Feasibility and Effects in Cutaneous Leishmaniasis Patients in Pakistan
The goal of this clinical trial is to learn whether immersive technology (virtual reality) headsets can reduce procedural pain and anxiety during diagnosis, intralesional and intramuscular injections, and wound/dressing care in…
- Conditions
- Cutaneous Leishmaniasis, Pain, Anxiety
- Trial name
- NCT07858357
- Testing
- Virtual Reality
- Volunteers
- 15 people
- Sponsor
- Stanford University
Diaphragm Injury
Janus Kinase Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction
We intend, with this study, to prove that blocking the molecular mechanisms whose blockade prevents VIDD in animals, will indeed prevent the development of VIDD in humans as well.
- Trial name
- NCT03681275
- Testing
- Tofacitinib 10 MG [Xeljanz]
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
IBS (Irritable Bowel Syndrome)
High-Resolution Measurements of Diet-Microbiome Interactions
The goal of this clinical trial is to characterize regional intestinal fermentation physiology and determine how the response to fermentable dietary fiber differs between healthy individuals and individuals with irritable bowel…
- Trial name
- NCT07856823
- Testing
- Inulin, Low-fiber control breakfast shake, Atmo Gas-Sensing Capsule
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University